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1.

Early-life respiratory infections and developmental immunity determine lifelong lung health.

Lloyd, Clare M; Saglani, Sejal.

Nat Immunol; 24(8): 1234-1243, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37414905

2.

Influence of age on clinical characteristics, pharmacological management and exacerbations in children with asthma.

Khalaf, Zainab; Bush, Andrew; Saglani, Sejal; Bloom, Chloe I.

Thorax; 79(2): 112-119, 2024 01 18.

Artículo en Inglés | MEDLINE | ID: mdl-38071524

3.

Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?

Saglani, Sejal; Yates, Laura; Lloyd, Clare M.

Eur J Immunol; 53(8): e2249919, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-36932669

4.

Role of epithelial barrier function in inducing type 2 immunity following early-life viral infection.

Tian, Kunyuan; Dangarh, Prakrati; Zhang, Haina; Hines, Christian L; Bush, Andrew; Pybus, Hannah J; Harker, James A; Lloyd, Clare M; Tanaka, Reiko J; Saglani, Sejal.

Clin Exp Allergy; 54(2): 109-119, 2024 02.

Artículo en Inglés | MEDLINE | ID: mdl-38011856

5.

WITHDRAWN: Update in Asthma 2021.

Saglani, Sejal; Cohen, Robyn T; Chiel, Laura E; Halayko, Andrew J; Pascoe, Christopher D; Custovic, Adnan.

Am J Respir Crit Care Med; 2022 05 05.

Artículo en Inglés | MEDLINE | ID: mdl-35511755

6.

Considering biomarkers in asthma disease severity.

Custovic, Adnan; Siddiqui, Salman; Saglani, Sejal.

J Allergy Clin Immunol; 149(2): 480-487, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34942235

7.

Airway inflammation in severe asthmatics with acid gastro-oesophageal reflux.

Tanner, Nicole; Saglani, Sejal; Li, Albert M; Bush, Andrew; Fleming, Louise.

Thorax; 77(4): 398-399, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-34497139

8.

Disadvantage in early-life and persistent asthma in adolescents: a UK cohort study.

Creese, Hanna; Lai, Eric; Mason, Kate; Schlüter, Daniela K; Saglani, Sejal; Taylor-Robinson, David; Saxena, Sonia.

Thorax; 77(9): 854-864, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-34650003

9.

Childhood asthma: pathogenesis and phenotypes.

Pijnenburg, Mariëlle W; Frey, Urs; De Jongste, Johan C; Saglani, Sejal.

Eur Respir J; 59(6)2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-34711541

10.

Opening the Window of Immune Opportunity: Treating Childhood Asthma.

Lloyd, Clare M; Saglani, Sejal.

Trends Immunol; 40(9): 786-798, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31420279

11.

Blood eosinophils in managing preschool wheeze: Lessons learnt from a proof-of-concept trial.

Saglani, Sejal; Bingham, Yvonne; Balfour-Lynn, Ian; Goldring, Stephen; Gupta, Atul; Banya, Winston; Moreiras, John; Fleming, Louise; Bush, Andrew; Rosenthal, Mark.

Pediatr Allergy Immunol; 33(1): e13697, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34783100

12.

Growth of the airway smooth muscle layer from late gestation to childhood is mediated initially by hypertrophy and subsequently hyperplasia.

Wang, Kimberley C W; Donovan, Graham M; Saglani, Sejal; Mauad, Thais; James, Alan L; Elliot, John G; Noble, Peter B.

Respirology; 27(7): 493-500, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35266251

13.

Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes.

Robinson, Polly F M; Fontanella, Sara; Ananth, Sachin; Martin Alonso, Aldara; Cook, James; Kaya-de Vries, Daphne; Polo Silveira, Luisa; Gregory, Lisa; Lloyd, Clare; Fleming, Louise; Bush, Andrew; Custovic, Adnan; Saglani, Sejal.

Am J Respir Crit Care Med; 204(5): 523-535, 2021 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-33961755

14.

Burden of preschool wheeze and progression to asthma in the UK: Population-based cohort 2007 to 2017.

Bloom, Chloe I; Franklin, Courtney; Bush, Andrew; Saglani, Sejal; Quint, Jennifer K.

J Allergy Clin Immunol; 147(5): 1949-1958, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33453287

15.

Airway macrophage-intrinsic TGF-ß1 regulates pulmonary immunity during early-life allergen exposure.

Branchett, William J; Cook, James; Oliver, Robert A; Bruno, Nicoletta; Walker, Simone A; Stölting, Helen; Mack, Matthias; O'Garra, Anne; Saglani, Sejal; Lloyd, Clare M.

J Allergy Clin Immunol; 147(5): 1892-1906, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33571538

16.

Pediatric problematic severe asthma: Recent advances in management.

Scotney, Elizabeth; Burchett, Saskia; Goddard, Thomas; Saglani, Sejal.

Pediatr Allergy Immunol; 32(7): 1405-1415, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34002877

17.

Safety of live attenuated influenza vaccine (LAIV) in children with moderate to severe asthma.

Turner, Paul J; Fleming, Louise; Saglani, Sejal; Southern, Jo; Andrews, Nick J; Miller, Elizabeth.

J Allergy Clin Immunol; 145(4): 1157-1164.e6, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31863808

18.

Development of allergic immunity in early life.

Lloyd, Clare M; Saglani, Sejal.

Immunol Rev; 278(1): 101-115, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28658545

19.

Impaired airway epithelial cell wound-healing capacity is associated with airway remodelling following RSV infection in severe preschool wheeze.

Andersson, Cecilia K; Iwasaki, Jua; Cook, James; Robinson, Polly; Nagakumar, Prasad; Mogren, Sofia; Fleming, Louise; Bush, Andrew; Saglani, Sejal; Lloyd, Clare M.

Allergy; 75(12): 3195-3207, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-32578219

20.

Childhood Asthma: Advances Using Machine Learning and Mechanistic Studies.

Saglani, Sejal; Custovic, Adnan.

Am J Respir Crit Care Med; 199(4): 414-422, 2019 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-30571146

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Early-life respiratory infections and developmental immunity determine lifelong lung health.

Influence of age on clinical characteristics, pharmacological management and exacerbations in children with asthma.

Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?

Role of epithelial barrier function in inducing type 2 immunity following early-life viral infection.

WITHDRAWN: Update in Asthma 2021.

Considering biomarkers in asthma disease severity.

Airway inflammation in severe asthmatics with acid gastro-oesophageal reflux.

Disadvantage in early-life and persistent asthma in adolescents: a UK cohort study.

Childhood asthma: pathogenesis and phenotypes.

Opening the Window of Immune Opportunity: Treating Childhood Asthma.

Blood eosinophils in managing preschool wheeze: Lessons learnt from a proof-of-concept trial.

Growth of the airway smooth muscle layer from late gestation to childhood is mediated initially by hypertrophy and subsequently hyperplasia.

Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes.

Burden of preschool wheeze and progression to asthma in the UK: Population-based cohort 2007 to 2017.

Airway macrophage-intrinsic TGF-ß1 regulates pulmonary immunity during early-life allergen exposure.

Pediatric problematic severe asthma: Recent advances in management.

Safety of live attenuated influenza vaccine (LAIV) in children with moderate to severe asthma.

Development of allergic immunity in early life.

Impaired airway epithelial cell wound-healing capacity is associated with airway remodelling following RSV infection in severe preschool wheeze.

Childhood Asthma: Advances Using Machine Learning and Mechanistic Studies.