RESUMEN
BACKGROUND: Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition; however, patients with GPA rarely experience endocardial valve lesions. METHODS: We report a GPA case with tricuspid valve destruction together with a systematic review to highlight the characteristics of all previously reported GPA cases with valvular involvement. RESULTS: Among 36 cases included, the aortic valve was involved in 15 (41.7%) cases while the mitral valve was involved in 9 (25%) subjects. Combined lesion of both aortic and mitral valves was reported in 9 (25%) patients. CONCLUSION: We recommend routine echocardiography examination to rule out any cardiac valve lesion once GPA is suspected.
Asunto(s)
Válvula Aórtica/fisiopatología , Ecocardiografía/métodos , Granulomatosis con Poliangitis/complicaciones , Enfermedades de las Válvulas Cardíacas/complicaciones , Válvula Mitral/fisiopatología , Adulto , Femenino , Granulomatosis con Poliangitis/fisiopatología , Enfermedades de las Válvulas Cardíacas/fisiopatología , HumanosRESUMEN
Immune profile assessment-particularly for SLE-and subsequent specific therapy are beneficial in patients with persisting unexplained hyperkalemic or hypokalemic paralysis, especially in case of isolated RTA.