Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Más filtros

Bases de datos
Tipo de estudio
Tipo del documento
Asunto de la revista
País de afiliación
Intervalo de año de publicación
1.
Nat Commun ; 12(1): 1148, 2021 02 19.
Artículo en Inglés | MEDLINE | ID: mdl-33608511

RESUMEN

The overuse of antibiotics is exacerbating the antibiotic resistance crisis. Since this problem is a classic common-goods dilemma, it naturally lends itself to a game-theoretic analysis. Hence, we designed a model wherein physicians weigh whether antibiotics should be prescribed, given that antibiotic usage depletes its future effectiveness. The physicians' decisions rely on the probability of a bacterial infection before definitive laboratory results are available. We show that the physicians' equilibrium decision rule of antibiotic prescription is not socially optimal. However, we prove that discretizing the information provided to physicians can mitigate the gap between their equilibrium decisions and the social optimum of antibiotic prescription. Despite this problem's complexity, the effectiveness of the discretization solely depends on the type of information available to the physician to determine the nature of infection. This is demonstrated on theoretic distributions and a clinical dataset. Our results provide a game-theory based guide for optimal output of current and future decision support systems of antibiotic prescription.


Asunto(s)
Antibacterianos , Farmacorresistencia Microbiana , Teoría del Juego , Antibacterianos/uso terapéutico , Infecciones Bacterianas/tratamiento farmacológico , Biología Computacional , Farmacorresistencia Bacteriana , Farmacorresistencia Viral , Humanos , Medicina Preventiva/métodos , Virosis
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA