Assessing the attitude of surgical trainees towards virtual reality simulation: A national cross-sectional questionnaire study.

BACKGROUND: We performed a cross sectional study to determine the attitudes of surgical trainees and medical students towards virtual reality (VR) simulation in surgical training. A survey was devised through an iterative process before distribution to surgical trainees, foundation year doctors and medical students through online platforms. METHODS: The survey was disseminated within the United Kingdom through social media and email correspondence, in co-operation with national surgical organisations. 91 trainees responded from a variety of clinical specialities. RESULTS: VR technology in surgical training was viewed positively, with 91.3% of trainees agreeing that VR should be both an adjunct in surgical training as well as a competency-based assessment tool. Barriers to access were present, with access notably more challenging for senior surgeons. CONCLUSION: Virtual reality surgical simulation in surgical training is beginning to emerge as a genuine high-fidelity, low-risk solution to the lack of surgical case volume trainees are currently experiencing.

Understanding angiogenesis and the role of angiogenic growth factors in the vascularisation of engineered tissues.

Tissue engineering is a rapidly developing field with many potential clinical applications in tissue and organ regeneration. The development of a mature and stable vasculature within these engineered tissues (ET) remains a significant obstacle. Currently, several growth factors (GFs) have been identified to play key roles within in vivo angiogenesis, including vascular endothelial growth factor (VEGF), platelet derived growth factor (PDGF), FGF and angiopoietins. In this article we attempt to build on in vivo principles to review the single, dual and multiple GF release systems and their effects on promoting angiogenesis. We conclude that multiple GF release systems offer superior results compared to single and dual systems with more stable, mature and larger vessels produced. However, with more complex release systems this raises other problems such as increased cost and significant GF-GF interactions. Upstream regulators and pericyte-coated scaffolds could provide viable alternative to circumnavigate these issues.

Syncope as a rare presentation of papillary thyroid cancer.

Syncope as a presentation for head and neck cancers is extremely rare. We report a case of a man in his 50s presenting with syncope and a left-sided neck mass. The diagnosis of syncope was secondary to a neck mass compressing the carotid body. After biopsy, it was found to be a metastatic papillary thyroid cancer for which the patient underwent a total thyroidectomy and neck dissection. We describe a workflow protocol for investigating patients presenting with syncope and associated neck mass. The work-up for such patients should include general, cardiological and otolaryngological-specific investigations.

ENT On-call Equipment Bag: Updated for COVID-19.

Otorhinolaryngology, or Ear Nose and throat (ENT), is a specialty requiring specific equipment for the management and treatment of patients. While most hospitals provide a 24/7 ENT procedure room, there is also a need for a mobile equipment bag with objects and instruments not readily available outside of the ENT department. We look to introduce a novel ENT equipment bag and checklist which has been updated to include a list of required equipment in the setting of the current COVID-19 pandemic. For the ENT equipment bag we use a high visibility multi-compartment bag. In addition to this, the bag contains four folders, labelled "Ear", "Nose", "Throat" and "Drugs". The necessary ENT equipment is divided and included within these folders. The bag also contains a copy of the "ENT bag checklist". This is a list, designed by the Whipps Cross ENT team, which specifies the required ENT equipment, including PPE in light of the current COVID-19 pandemic. The bag is stocked once a week using this list. Using this new system we developed a portable, practical and easy to use ENT on call equipment bag that included all of the relevant PPE to manage COVID-19 patients. We also implemented a new method of bag stocking to ensure that the bag is adequately stocked. In conclusion, we present a COVID-19 updated ENT bag and checklist. We hope this will help act as a reference for other ENT teams to compare and implement during the current COVID-19 pandemic.

Intraoperative Sneezing Secondary to Indirect Olfactory Nerve Stimulation.

Sneezing is a poorly understood, protective reflex response. It's characterized by the following sequence: eye closure, inspiration, glottic closure, forced expiration with sudden glottic opening, and release of an elevated intrathoracic pressure creating a flow of explosive air through the nose.1 Studies have indicated an anatomic sneezing area of the brainstem corresponding to the central recipient zone of the nasal sensory neurons in the lateral medulla.2 The traditional pathophysiology of the sneeze is thought to begin by stimulation of the distal branches of the trigeminal nerve within the nasal mucosa. Afferent neural stimuli are transmitted to the trigeminal ganglion and then the lateral medulla. The efferent phase then begins, giving rise to the sneezing sequence described earlier.1 In addition to direct nasal irritation, sneezing has been shown to be triggered by several other causes (Table 1). This suggests that alternative mechanisms of sneeze induction other than direct nasal stimulation exist. We report a case of a 34-year-old man undergoing an awake craniotomy for a recurrent World Health Organization grade 2 oligodendroglioma (IDH-mutant, 1p19q-codeleted, ATRX preserved). During the operation we elicited a sneeze response on 3 occasions on stimulation of the olfactory nerve (Video 1). Although we cannot completely exclude costimulation of the sensory trigeminal terminations in the anterior fossa floor, the actual sneezing occurred during tumor peeling away from the arachnoid surface overlaying the olfactory nerve. This suggests a potential accessory route of sneeze stimulation involving the olfactory nerve distinct from the previously described trigemino-related, autonomic (sympathetic and parasympathetic systems) and psychogenic etiologies.

Sleep in elite swimmers: prevalence of sleepiness, obstructive sleep apnoea and poor sleep quality.

OBJECTIVES: Limited data suggest that swimmers might be affected by poor quality of sleep significantly. The aim was to explore the prevalence of sleep disturbances in swimmers and possible link between rhinitis and sleep disturbance. METHODS: Study 1 was an observational case-control, questionnaire-based study involving 157 elite and non-elite swimmers, 36 non-swimming athletes and 50 controls. In study 2, we measured sleep quality and duration using actigraphy in 20 elite swimmers. We also looked for presence of sleep-disordered breathing using overnight pulse oximetry monitor. RESULTS: In study 1, we observed a significant difference in prevalence of excessive daytime sleepiness between groups of elite swimmers and controls. Pittsburgh Sleep Quality Index (PSQI) scores do not suggest that quality of sleep in group of swimmers is impaired. In study 2, we found that prevalence of obstructive sleep apnoea (OSA) in elite swimmers defined as oxygen desaturation index ≥5 was 30%. Analysis of actigraphy data revealed that on nights prior to training days, 'going to' bed time was significantly earlier and total sleep time was significantly reduced. CONCLUSION: Swimmers and non-swimming athletes suffer significantly more with excessive daytime sleepiness than healthy controls. In elite swimmers, this is likely linked to high prevalence of OSA. PSQI scores do not suggest that quality of sleep in group of swimmers is impaired, but actigraphy shows great variations between sleep pattern preceding training and rest day. This seems to be associated with early-morning sessions which can be a disruptive element of weekly sleep patterns.