Bone damage and health-related quality of life in Hodgkin lymphoma survivors: closing the gaps.

In the recent decades, remarkable successes have been recorded in the treatment of Hodgkin's lymphoma to the point that today it represents one of the neoplasms with the highest rates of cure and with the highest life expectancy. Nonetheless, this raises the concern for the health of long- term survivors. Late side effects of treatments in synergy with other risk factors expose survivors to increased morbidity and impaired quality of life. In the complexity of the topics concerning these last aspects, an area of growing interest is that of bone damage that follows Hodgkin Lymphoma and its treatments. In this narrative review, we conducted our work through assessment of available evidence focusing on several aspects linking bone damage and quality of life with Hodgkin lymphoma and its treatments. At present, the problem of osteopenia and osteoporosis in Hodgkin lymphoma survivors is a theme for which awareness and knowledge need to be implemented.

A Difficult Case of Ventriculitis in a 40-Year-Old Woman with Acute Myeloid Leukemia.

Ventriculitis and nosocomial meningitis caused by carbapenem-resistant Gram-negative and vancomycin-resistant Gram-positive bacteria represent a growing treatment challenge. A case of ventriculitis and bacteremia caused by carbapenem-resistant, KPC-producing Klebsiella pneumoniae and vancomycin-resistant Enterococcus faecium in a young woman with acute leukemia who was successfully treated with meropenem/vaborbactam (MVB), rifampicin, and linezolid is described in this paper. This case report emphasizes the importance of a multidisciplinary strategy, including infectious focus control, for the treatment of device-associated central nervous system (CNS) infections from multidrug-resistant bacteria. Considering the novel resistance patterns, more research on drug penetration into the central nervous system, as well as on the necessity of association therapies, is needed.

Miíase humana bucal por cochliomyia hominivorax (Coquerel, 1858) em Nova Esperança, estado do Paraná, Brasil / Human oral myiasis by cochliomyia hominivorax (Coquerel, 1858) in Nova Esperança, Paraná state, Brazil

Miiases são infestações de tecidos vivos ou necrosados por larvas de dípteros, da subordem dos ciclorrafos (moscas). Embora consideradas raras, as miíases humanas têm sido descritas no norte, no centro e no sul da América. Neste trabalho, os autores apresentam o relato de um caso de miíase oral por Cochilio,yia hominivorax, cuja patologia em cavidade bucal foi pouco relatada