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1.
Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
PLoS Genet;
15(6): e1008226, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31199789
2.
Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo.
Mamm Genome;
31(9-12): 287-294, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33247772
3.
Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
Gene Ther;
25(4): 297-311, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29789638
4.
Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice.
Mamm Genome;
28(9-10): 407-415, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28547032
5.
Chronic dry eye symptoms after LASIK: parallels and lessons to be learned from other persistent post-operative pain disorders.
Mol Pain;
11: 21, 2015 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25896684
6.
rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.
Front Mol Neurosci;
17: 1398839, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38783904
7.
Neuropathic ocular surface pain: Emerging drug targets and therapeutic implications.
Expert Opin Ther Targets;
26(8): 681-695, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36069761
8.
Differential Effects of Treatment Strategies in Individuals With Chronic Ocular Surface Pain With a Neuropathic Component.
Front Pharmacol;
12: 788524, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-35002721
9.
Periorbital botulinum toxin A improves photophobia and sensations of dryness in patients without migraine: Case series of four patients.
Am J Ophthalmol Case Rep;
19: 100809, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32671286
10.
Neuropathic pain and dry eye.
Ocul Surf;
16(1): 31-44, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29031645
11.
The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis).
Trans Am Ophthalmol Soc;
115: T5, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-29391860
12.
Patients with more severe symptoms of neuropathic ocular pain report more frequent and severe chronic overlapping pain conditions and psychiatric disease.
Br J Ophthalmol;
101(2): 227-231, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27130915
13.
Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain.
Br J Ophthalmol;
101(9): 1238-1243, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28100479
14.
Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice.
Neuroreport;
28(18): 1215-1220, 2017 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28902707
15.
ω-3 Tear Film Lipids Correlate With Clinical Measures of Dry Eye.
Invest Ophthalmol Vis Sci;
57(6): 2472-8, 2016 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27138739
16.
Incomplete response to artificial tears is associated with features of neuropathic ocular pain.
Br J Ophthalmol;
100(6): 745-9, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26377416
17.
Dry Eye Profiles in Patients with a Positive Elevated Surface Matrix Metalloproteinase 9 Point-of-Care Test Versus Negative Patients.
Ocul Surf;
14(2): 216-23, 2016 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26807724
18.
Neuropathic Ocular Pain due to Dry Eye is Associated with Multiple Comorbid Chronic Pain Syndromes.
J Pain;
17(3): 310-8, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26606863
19.
Dry eye symptom severity and persistence are associated with symptoms of neuropathic pain.
Br J Ophthalmol;
99(5): 665-8, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25336572
20.
Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.
PLoS One;
10(3): e0118273, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25734498
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