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1.

Haunting innate immune memories of COVID-19.

Sawitzki, Birgit.

Cell; 186(18): 3753-3755, 2023 08 31.

Artículo en Inglés | MEDLINE | ID: mdl-37657416

2.

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.

Wendisch, Daniel; Dietrich, Oliver; Mari, Tommaso; von Stillfried, Saskia; Ibarra, Ignacio L; Mittermaier, Mirja; Mache, Christin; Chua, Robert Lorenz; Knoll, Rainer; Timm, Sara; Brumhard, Sophia; Krammer, Tobias; Zauber, Henrik; Hiller, Anna Luisa; Pascual-Reguant, Anna; Mothes, Ronja; Bülow, Roman David; Schulze, Jessica; Leipold, Alexander M; Djudjaj, Sonja; Erhard, Florian; Geffers, Robert; Pott, Fabian; Kazmierski, Julia; Radke, Josefine; Pergantis, Panagiotis; Baßler, Kevin; Conrad, Claudia; Aschenbrenner, Anna C; Sawitzki, Birgit; Landthaler, Markus; Wyler, Emanuel; Horst, David; Hippenstiel, Stefan; Hocke, Andreas; Heppner, Frank L; Uhrig, Alexander; Garcia, Carmen; Machleidt, Felix; Herold, Susanne; Elezkurtaj, Sefer; Thibeault, Charlotte; Witzenrath, Martin; Cochain, Clément; Suttorp, Norbert; Drosten, Christian; Goffinet, Christine; Kurth, Florian; Schultze, Joachim L; Radbruch, Helena.

Cell; 184(26): 6243-6261.e27, 2021 12 22.

Artículo en Inglés | MEDLINE | ID: mdl-34914922

3.

CD4⁺ T cell calibration of antigen-presenting cells optimizes antiviral CD8⁺ T cell immunity.

Gressier, Elise; Schulte-Schrepping, Jonas; Petrov, Lev; Brumhard, Sophia; Stubbemann, Paula; Hiller, Anna; Obermayer, Benedikt; Spitzer, Jasper; Kostevc, Tomislav; Whitney, Paul G; Bachem, Annabell; Odainic, Alexandru; van de Sandt, Carolien; Nguyen, Thi H O; Ashhurst, Thomas; Wilson, Kayla; Oates, Clare V L; Gearing, Linden J; Meischel, Tina; Hochheiser, Katharina; Greyer, Marie; Clarke, Michele; Kreutzenbeck, Maike; Gabriel, Sarah S; Kastenmüller, Wolfgang; Kurts, Christian; Londrigan, Sarah L; Kallies, Axel; Kedzierska, Katherine; Hertzog, Paul J; Latz, Eicke; Chen, Yu-Chen E; Radford, Kristen J; Chopin, Michael; Schroeder, Jan; Kurth, Florian; Gebhardt, Thomas; Sander, Leif E; Sawitzki, Birgit; Schultze, Joachim L; Schmidt, Susanne V; Bedoui, Sammy.

Nat Immunol; 24(6): 979-990, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37188942

4.

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans.

Bacher, Petra; Heinrich, Frederik; Stervbo, Ulrik; Nienen, Mikalai; Vahldieck, Marco; Iwert, Christina; Vogt, Katrin; Kollet, Jutta; Babel, Nina; Sawitzki, Birgit; Schwarz, Carsten; Bereswill, Stefan; Heimesaat, Markus M; Heine, Guido; Gadermaier, Gabriele; Asam, Claudia; Assenmacher, Mario; Kniemeyer, Olaf; Brakhage, Axel A; Ferreira, Fátima; Wallner, Michael; Worm, Margitta; Scheffold, Alexander.

Cell; 167(4): 1067-1078.e16, 2016 11 03.

Artículo en Inglés | MEDLINE | ID: mdl-27773482

5.

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

Krämer, Benjamin; Knoll, Rainer; Bonaguro, Lorenzo; ToVinh, Michael; Raabe, Jan; Astaburuaga-García, Rosario; Schulte-Schrepping, Jonas; Kaiser, Kim Melanie; Rieke, Gereon J; Bischoff, Jenny; Monin, Malte B; Hoffmeister, Christoph; Schlabe, Stefan; De Domenico, Elena; Reusch, Nico; Händler, Kristian; Reynolds, Gary; Blüthgen, Nils; Hack, Gudrun; Finnemann, Claudia; Nischalke, Hans D; Strassburg, Christian P; Stephenson, Emily; Su, Yapeng; Gardner, Louis; Yuan, Dan; Chen, Daniel; Goldman, Jason; Rosenstiel, Philipp; Schmidt, Susanne V; Latz, Eicke; Hrusovsky, Kevin; Ball, Andrew J; Johnson, Joe M; Koenig, Paul-Albert; Schmidt, Florian I; Haniffa, Muzlifah; Heath, James R; Kümmerer, Beate M; Keitel, Verena; Jensen, Björn; Stubbemann, Paula; Kurth, Florian; Sander, Leif E; Sawitzki, Birgit; Aschenbrenner, Anna C; Schultze, Joachim L; Nattermann, Jacob.

Immunity; 54(11): 2650-2669.e14, 2021 11 09.

Artículo en Inglés | MEDLINE | ID: mdl-34592166

6.

Untimely TGFß responses in COVID-19 limit antiviral functions of NK cells.

Witkowski, Mario; Tizian, Caroline; Ferreira-Gomes, Marta; Niemeyer, Daniela; Jones, Terry C; Heinrich, Frederik; Frischbutter, Stefan; Angermair, Stefan; Hohnstein, Thordis; Mattiola, Irene; Nawrath, Philipp; McEwen, Sophie; Zocche, Silvia; Viviano, Edoardo; Heinz, Gitta Anne; Maurer, Marcus; Kölsch, Uwe; Chua, Robert Lorenz; Aschman, Tom; Meisel, Christian; Radke, Josefine; Sawitzki, Birgit; Roehmel, Jobst; Allers, Kristina; Moos, Verena; Schneider, Thomas; Hanitsch, Leif; Mall, Marcus A; Conrad, Christian; Radbruch, Helena; Duerr, Claudia U; Trapani, Joseph A; Marcenaro, Emanuela; Kallinich, Tilmann; Corman, Victor M; Kurth, Florian; Sander, Leif Erik; Drosten, Christian; Treskatsch, Sascha; Durek, Pawel; Kruglov, Andrey; Radbruch, Andreas; Mashreghi, Mir-Farzin; Diefenbach, Andreas.

Nature; 600(7888): 295-301, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34695836

7.

Epigenomic Profiling of Human CD4⁺ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.

Durek, Pawel; Nordström, Karl; Gasparoni, Gilles; Salhab, Abdulrahman; Kressler, Christopher; de Almeida, Melanie; Bassler, Kevin; Ulas, Thomas; Schmidt, Florian; Xiong, Jieyi; Glazar, Petar; Klironomos, Filippos; Sinha, Anupam; Kinkley, Sarah; Yang, Xinyi; Arrigoni, Laura; Amirabad, Azim Dehghani; Ardakani, Fatemeh Behjati; Feuerbach, Lars; Gorka, Oliver; Ebert, Peter; Müller, Fabian; Li, Na; Frischbutter, Stefan; Schlickeiser, Stephan; Cendon, Carla; Fröhler, Sebastian; Felder, Bärbel; Gasparoni, Nina; Imbusch, Charles D; Hutter, Barbara; Zipprich, Gideon; Tauchmann, Yvonne; Reinke, Simon; Wassilew, Georgi; Hoffmann, Ute; Richter, Andreas S; Sieverling, Lina; Chang, Hyun-Dong; Syrbe, Uta; Kalus, Ulrich; Eils, Jürgen; Brors, Benedikt; Manke, Thomas; Ruland, Jürgen; Lengauer, Thomas; Rajewsky, Nikolaus; Chen, Wei; Dong, Jun; Sawitzki, Birgit.

Immunity; 45(5): 1148-1161, 2016 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-27851915

8.

A Phase I/IIa study of autologous tolerogenic dendritic cells immunotherapy in kidney transplant recipients.

Moreau, Aurélie; Kervella, Delphine; Bouchet-Delbos, Laurence; Braudeau, Cécile; Saïagh, Soraya; Guérif, Pierrick; Limou, Sophie; Moreau, Anne; Bercegeay, Sylvain; Streitz, Mathias; Sawitzki, Birgit; James, Ben; Harden, Paul N; Game, David; Tang, Qizhi; Markmann, James F; Roberts, Ian S D; Geissler, Edward K; Dréno, Brigitte; Josien, Régis; Cuturi, Maria-Cristina; Blancho, Gilles.

Kidney Int; 103(3): 627-637, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36306921

9.

Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial.

Guinan, Eva C; Contreras-Ruiz, Laura; Crisalli, Kerry; Rickert, Charles; Rosales, Ivy; Makar, Robert; Colvin, Robert; Geissler, Edward K; Sawitzki, Birgit; Harden, Paul; Tang, Qizhi; Blancho, Giles; Turka, Laurence A; Markmann, James F.

Am J Transplant; 23(12): 1872-1881, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-37422112

10.

SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.

Meyer-Arndt, Lil; Braun, Julian; Fauchere, Florent; Vanshylla, Kanika; Loyal, Lucie; Henze, Larissa; Kruse, Beate; Dingeldey, Manuela; Jürchott, Karsten; Mangold, Maike; Maraj, Ardit; Braginets, Andre; Böttcher, Chotima; Nitsche, Andreas; de la Rosa, Kathrin; Ratswohl, Christoph; Sawitzki, Birgit; Holenya, Pavlo; Reimer, Ulf; Sander, Leif E; Klein, Florian; Paul, Friedemann; Bellmann-Strobl, Judith; Thiel, Andreas; Giesecke-Thiel, Claudia.

J Neurol Neurosurg Psychiatry; 93(9): 960-971, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35835468

11.

Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients.

Harden, Paul N; Game, David S; Sawitzki, Birgit; Van der Net, Jeroen B; Hester, Joanna; Bushell, Andrew; Issa, Fadi; Brook, Matthew O; Alzhrani, Alaa; Schlickeiser, Stephan; Scotta, Cristiano; Petchey, William; Streitz, Mathias; Blancho, Gilles; Tang, Quizhi; Markmann, James; Lechler, Robert I; Roberts, Ian S D; Friend, Peter J; Hilton, Rachel; Geissler, Edward K; Wood, Kathryn J; Lombardi, Giovanna.

Am J Transplant; 21(4): 1603-1611, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33171020

12.

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

Sawitzki, Birgit; Harden, Paul N; Reinke, Petra; Moreau, Aurélie; Hutchinson, James A; Game, David S; Tang, Qizhi; Guinan, Eva C; Battaglia, Manuela; Burlingham, William J; Roberts, Ian S D; Streitz, Mathias; Josien, Régis; Böger, Carsten A; Scottà, Cristiano; Markmann, James F; Hester, Joanna L; Juerchott, Karsten; Braudeau, Cecile; James, Ben; Contreras-Ruiz, Laura; van der Net, Jeroen B; Bergler, Tobias; Caldara, Rossana; Petchey, William; Edinger, Matthias; Dupas, Nathalie; Kapinsky, Michael; Mutzbauer, Ingrid; Otto, Natalie M; Öllinger, Robert; Hernandez-Fuentes, Maria P; Issa, Fadi; Ahrens, Norbert; Meyenberg, Christoph; Karitzky, Sandra; Kunzendorf, Ulrich; Knechtle, Stuart J; Grinyó, Josep; Morris, Peter J; Brent, Leslie; Bushell, Andrew; Turka, Laurence A; Bluestone, Jeffrey A; Lechler, Robert I; Schlitt, Hans J; Cuturi, Maria C; Schlickeiser, Stephan; Friend, Peter J; Miloud, Tewfik.

Lancet; 395(10237): 1627-1639, 2020 05 23.

Artículo en Inglés | MEDLINE | ID: mdl-32446407

13.

Risk factors for Epstein-Barr virus reactivation after renal transplantation: Results of a large, multi-centre study.

Blazquez-Navarro, Arturo; Dang-Heine, Chantip; Wehler, Patrizia; Roch, Toralf; Bauer, Chris; Neumann, Sindy; Blazquez-Navarro, Rodrigo; Kurchenko, Andriy; Wolk, Kerstin; Sabat, Robert; Westhoff, Timm H; Olek, Sven; Thomusch, Oliver; Seitz, Harald; Reinke, Petra; Hugo, Christian; Sawitzki, Birgit; Or-Guil, Michal; Babel, Nina.

Transpl Int; 34(9): 1680-1688, 2021 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-34448272

14.

CD96 expression determines the inflammatory potential of IL-9-producing Th9 cells.

Stanko, Katarina; Iwert, Christina; Appelt, Christine; Vogt, Katrin; Schumann, Julia; Strunk, Franziska Janina; Ahrlich, Stefanie; Schlickeiser, Stephan; Romagnani, Chiara; Jürchott, Karsten; Meisel, Christian; Willimsky, Gerald; Kühl, Anja A; Sawitzki, Birgit.

Proc Natl Acad Sci U S A; 115(13): E2940-E2949, 2018 03 27.

Artículo en Inglés | MEDLINE | ID: mdl-29531070

15.

A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection in renal transplantation.

Wittenbrink, Nicole; Herrmann, Sabrina; Blazquez-Navarro, Arturo; Bauer, Chris; Lindberg, Eric; Wolk, Kerstin; Sabat, Robert; Reinke, Petra; Sawitzki, Birgit; Thomusch, Oliver; Hugo, Christian; Babel, Nina; Seitz, Harald; Or-Guil, Michal.

BMC Immunol; 20(1): 11, 2019 04 27.

Artículo en Inglés | MEDLINE | ID: mdl-31029086

16.

Short-term cytokine stimulation reveals regulatory T cells with down-regulated Foxp3 expression in human peripheral blood.

Tabares, Paula; Berr, Susanne; Langenhorst, Daniela; Sawitzki, Birgit; Ten Berge, Ineke; Tony, Hans-Peter; Hünig, Thomas.

Eur J Immunol; 48(2): 366-379, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29023682

17.

Immune monitoring in renal transplantation: The search for biomarkers.

Danger, Richard; Sawitzki, Birgit; Brouard, Sophie.

Eur J Immunol; 46(12): 2695-2704, 2016 12.

Artículo en Inglés | MEDLINE | ID: mdl-27861809

18.

Wild immunology assessed by multidimensional mass cytometry.

Japp, Alberto Sada; Hoffmann, Kerstin; Schlickeiser, Stephan; Glauben, Rainer; Nikolaou, Christos; Maecker, Holden T; Braun, Julian; Matzmohr, Nadine; Sawitzki, Birgit; Siegmund, Britta; Radbruch, Andreas; Volk, Hans-Dieter; Frentsch, Marco; Kunkel, Desiree; Thiel, Andreas.

Cytometry A; 91(1): 85-95, 2017 01.

Artículo en Inglés | MEDLINE | ID: mdl-27403624

19.

TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production.

Vogel, Simone Z; Schlickeiser, Stephan; Jürchott, Karsten; Akyuez, Levent; Schumann, Julia; Appelt, Christine; Vogt, Katrin; Schröder, Martina; Vaeth, Martin; Berberich-Siebelt, Friederike; Lutz, Manfred B; Grütz, Gerald; Sawitzki, Birgit.

J Immunol; 194(7): 3136-46, 2015 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-25750433

20.

Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients.

Farschtschi, Said; Park, Su-Jin; Sawitzki, Birgit; Oh, Su-Jun; Kluwe, Lan; Mautner, Victor F; Kurtz, Andreas.

Cancer Immunol Immunother; 65(9): 1113-21, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27448806

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