RESUMEN
Examining the risk perception of one of the most life-threatening cancers among women, such as cervical cancer, will guide the development of targeted advocacy and educational programs to reduce the burden of the disease. The current study investigated cervical cancer perceived risks and associated factors among Saudi women. A cross-sectional study was conducted through a social media-based survey, which conveniently targeted 1085 Saudi women in Najran city. The survey questionnaire consisted of four parts: basic sociodemographic data, cervical cancer knowledge quiz, attitude scale, and risk perception Scale. The present study confirmed that 57.4% of the study participants had high-risk perception regarding cervical cancer. Among the study participants, 42.6% had a low perception of the risk of cervical cancer, 57.3% had unsatisfactory knowledge, while 59.4% had a positive attitude (59.4%) towards cervical cancer prevention and its screening. The binary logistic regression proved that the positive significant factors associated with risk perception were higher education [AOR=3.105 (1.300 - 7.418), p=0.011], increasing age [AOR=1.191 (1.043-1.359), p=0.005], longer duration of marriage [AOR=3.123 (1.112 - 8.767), p=0.031], having family history of cancer/cervical cancer [AOR=4.498 (1.119 - 18.085), p=0.034], satisfactory knowledge [AOR=2.304 (1.289 - 4.116), p=0.005], and positive attitude [AOR=3.248 (2.532 - 4.166), p=0.000]. We conclude that more than half of the women in Najran city had high cervical cancer-related risk perception while more than two-fifths perceived low risk with unsatisfactory knowledge and a positive attitude. These results highlight the pressing need to develop cervical cancer health education programs to foster risk perception as a driving strategy for the prevention of cervical cancer in Saudi Arabian women.
Asunto(s)
Neoplasias del Cuello Uterino , Humanos , Femenino , Neoplasias del Cuello Uterino/epidemiología , Neoplasias del Cuello Uterino/prevención & control , Neoplasias del Cuello Uterino/diagnóstico , Arabia Saudita/epidemiología , Estudios Transversales , Cuello del Útero , Educación en Salud , Conocimientos, Actitudes y Práctica en SaludRESUMEN
This study explores the predictors of cervical cancer (CC) knowledge and attitude among Saudi women in Najran city. A descriptive cross-sectional study was conducted in Najran/ KSA to recruit 1085 participants from June to September 2021. An online self-reported questionnaire was used for data collection; it consisted of basic data and health history, a CC knowledge quiz, and a CC attitude scale. Data analysis was performed using the Statistical IBM software, version 23 (IBM Corp., Armonk, N.Y., USA)'. The findings revealed that more than half of the participants (57.7%) had insufficient knowledge regarding CC. At the same time, 59.4% of them had a positive attitude toward CC screening. According to binary logistic regression analysis, University-educated participants had increased odds of sufficient knowledge (OR: 1.774, 95%CI1.101-2.856) and positive attitude (OR: 4.246, 95%CI 1.545-11.669) about CC compared to the participant with secondary education. Moreover, participants with no family history of CC were less likely to have sufficient knowledge (OR: 0.554, 95%CI 0.102-2.745) and positive attitude (OR: 0.867, 95%CI 0.776 - 0.968) about CC compared to participants with positive family history. Also, sufficient knowledge was statistically associated with a positive attitude (OR: 1.754, 95%CI 1.112-2.849). Among all basic variables, participants' educational qualifications and positive family history of CC are significant socio-demographic predictors of CC knowledge and attitude. Specific educational interventions to enhance women's knowledge and attitude toward CC screening should be developed and implemented in the community without delay, particularly for less-educated women.
Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Neoplasias del Cuello Uterino , Mujeres , Femenino , Humanos , Estudios Transversales , Escolaridad , Arabia Saudita , Neoplasias del Cuello Uterino/prevención & control , Neoplasias del Cuello Uterino/psicología , Mujeres/psicología , Ciudades , Encuestas y Cuestionarios , Detección Precoz del Cáncer/psicología , AnamnesisRESUMEN
In the Kingdom of Saudi Arabia (KSA), Cervical Cancer (CC) ranked fourth in incidence and associated mortality among all cancers, with a mean age incidence of 61 years. This study evaluates the perceived barriers to CC screening among Saudi women in Najran city, KSA. A cross-sectional study was conducted in Najran/ KSA, involving 1085 females. The data collection instrument comprised three main parts: basic data questionnaire, women's knowledge regarding CC screening, assessment of health belief model scale for CC, and Pap smear test. Data collection started through an online survey from the beginning of October 2021 till the end of January 2022. Data analyses were performed using the Statistical IBM software, version 23 (IBM Corp., Armonk, N.Y., USA). The results showed that fear of bad results (68.9%), cost of treatment (58.8%), embarrassment (59.9%), and preference for female physician (47.4%) among several others were the barriers to CC screening identified by women Over 61% of the participants had a moderate barrier to CC screening, and 24.8% had high perceived barriers. Ordinal logistic regression shows that age, higher education, high monthly income, positive family history for CC, and adequate CC screening knowledge are positive predictors of low CC screening barriers (pË0.05). Increasing number of deliveries and parities was a negative predictor for low CC screening. CC screening barriers are still high among Saudi females. Some demographic variables may predict low CC screening barriers, and health care providers should consider these variables during CC preventive and educational programs.
Asunto(s)
Neoplasias del Cuello Uterino , Femenino , Humanos , Persona de Mediana Edad , Neoplasias del Cuello Uterino/diagnóstico , Neoplasias del Cuello Uterino/prevención & control , Neoplasias del Cuello Uterino/epidemiología , Frotis Vaginal , Estudios Transversales , Detección Precoz del Cáncer , Arabia Saudita/epidemiología , Conocimientos, Actitudes y Práctica en Salud , Tamizaje MasivoRESUMEN
According to Saudi Arabia's 2030 vision, research should be directed to promote health and prevent diseases like cervical cancer (CC). Furthermore, the Kingdom pays specific attention to the health of women. CC ranks eighth among all cancers in Saudi Arabia; therefore, determining women's beliefs and associated factors will help prevent and treat them early. The objective of this study was to explore Saudi women's health beliefs and associated factors regarding CC prevention in Najran city. A cross-sectional design was carried out using a convenience sampling technique of 1085 participants from the Najran region. Data collection was done from June to September 2021, using tools consisting of basic data and personal/family history of the study participants and the health belief model (HBM) scale for CC. The findings revealed that up to 99% of the participants did not take the HPV vaccine, while only 2% undertook the Pap smear test. Less than one-fifth (17.9%) of the participants believed they were highly susceptible to developing CC, although more than two-thirds (70.4%) of them believed CC is a serious disease. Only one-tenth (9.8%) of the participants had low perceived barriers to undergoing a Pap smear test, even though a large proportion (85.3%) of them highly perceived its benefits and were motivated to uptake CC prevention. Rural area residence, low education, insufficient monthly income, and young age were negatively associated factors with CC prevention and health beliefs (p< 0.05). Participants with a family history of CC or who previously performed Pap smear test had a higher health motivation and perceived benefits of CC screening and prevention (p<0.05). The study concluded that most Saudi women did not undertake Pap smear tests or HPV vaccine, although average scores of the sub-dimensions of the HBM scale about CC were moderate or high except for perceived susceptibility to CC. Therefore, national educational programs for Saudi women should be directed to increase their perceived susceptibility to CC and decrease the perceived barriers to Pap smear test. In addition, the ministry of health's educational efforts should be directed to rural areas' residents with low education, insufficient monthly income, and young age women.
Asunto(s)
Vacunas contra Papillomavirus , Neoplasias del Cuello Uterino , Femenino , Humanos , Frotis Vaginal , Neoplasias del Cuello Uterino/diagnóstico , Promoción de la Salud , Estudios Transversales , Arabia Saudita/epidemiología , Encuestas y Cuestionarios , Conocimientos, Actitudes y Práctica en Salud , Prueba de Papanicolaou , Vacunas contra Papillomavirus/uso terapéuticoRESUMEN
Exploring the women's intention of the core self-directed behaviors for cervical cancer prevention and their confident abilities for engagement is of utmost importance for targeted intervention development. This study investigates the Saudi women's intention and self-efficacy for Pap Smear Screening and HPV Vaccination in Najran city, KSA. It was a descriptive cross-sectional study incorporating a convenient sample of 1085 Saudi women through a social media-based four-part questionnaire: Basic Data and Reproductive Health History, Pap Smear Intention Scale, HPV vaccination intention scale, Self-Efficacy Scale for Pap smear testing, and HPV vaccination. The results indicated that 59.5% of the study participants had a low intention for Pap testing, while 62.5% of them had a high intention to receive the HPV vaccine, and the self-efficacy for both was high among 57.0% of them. Binary logistic regression showed higher odds for Pap testing intention among older women with enough family income and those with no history of Pap testing and higher gravidity and parity. Rural resident women and those having no family history of CC have Lower odds for HPV vaccination intention. Women of reproductive age and those with high gravidity and parity have higher odds. Self-efficacy has lower odds among divorced, rural resident women and those with no history of Pap testing or HPV vaccine; however, women with longer marriage duration and higher gravidity and parity had higher odds. Hence, there is an apparent high intention for HPV vaccination with a low intention for Pap testing among Saudi women in Najran despite having a higher self-efficacy. These necessitate establishing consolidated efforts for awareness-raising and advocacy programs to prevent CC.
Asunto(s)
Infecciones por Papillomavirus , Vacunas contra Papillomavirus , Neoplasias del Cuello Uterino , Embarazo , Femenino , Humanos , Anciano , Prueba de Papanicolaou , Frotis Vaginal , Virus del Papiloma Humano , Intención , Autoeficacia , Infecciones por Papillomavirus/diagnóstico , Infecciones por Papillomavirus/prevención & control , Estudios Transversales , Arabia Saudita , Neoplasias del Cuello Uterino/diagnóstico , Neoplasias del Cuello Uterino/prevención & control , Vacunación , Vacunas contra Papillomavirus/uso terapéutico , Detección Precoz del Cáncer , Conocimientos, Actitudes y Práctica en Salud , Tamizaje MasivoRESUMEN
Deaf people experience barriers to communication that prevent access to health care and information that puts them at increased risk for lack of knowledge about prevention and early detection approaches to cancers. With decreased screening, they may be at a higher risk of discovering cervical cancer (CC) at a late stage. This study aimed to evaluate the impact of an educational intervention on deaf and hard hearing females' knowledge and health belief regarding cervical cancer in Tabuk, Saudi Arabia. A quasi-experimental study was performed from the beginning of April till the end of October 2021 using a convenience sample of 33 deaf and hard hearing married females students from Al-Amal center for deaf and hard hearing females and Tabuk University. The data were collected using an interview schedule composed of three parts translated to American Sign Language: background variables (basic data), cervical cancer knowledge quiz, and health belief model scale for CC and Pap smear test. About 75.8% of the participants were older than 20 years. The intervention-based HBM showed significant improvement in the overall knowledge score after the intervention compared to pre-intervention (FET = 16.345 P = 0.000). Moreover, significant enhancements (P <0.05) in all HBM construct scores after the HBM intervention compared to the pre-intervention. HBM-based educational interventions can be useful educational modalities for deaf and hard hearing populations. This intervention effectively enhanced the deaf and hard hearing females' overall knowledge and health beliefs scores.
Asunto(s)
Pérdida Auditiva , Personas con Deficiencia Auditiva , Neoplasias del Cuello Uterino , Humanos , Femenino , Neoplasias del Cuello Uterino/prevención & control , Neoplasias del Cuello Uterino/diagnóstico , Arabia Saudita , Conocimientos, Actitudes y Práctica en Salud , AudiciónRESUMEN
The government in Saudi Arabia in 2016 declared the necessity to overcome the ancestral oil-based economy and move towards a more diversified model. One of the significant steps to achieve this goal is to empower Saudi women, who form half of the Saudi population, to actively contribute their much-needed talents and skills to the Saudi labour market. However, there is a scarcity of existing scales to measure women empowerment in Saudi Arabia. The objective of this study was to construct and validate a reliable novel scale for the empowerment of Saudi women employed in higher education institutions. A methodological study was conducted from January to April 2020 among Saudi women academic and administrative staff (n=160) working in the higher educational institutions located in the northwestern and southern regions of Saudi Arabia. The tool underwent content and face validity as well as factor analyses. Internal consistency was analyzed through Cronbach's alpha and Pearson correlation coefficient. The data analysis was conducted using IBM SPSS version 23. A Cronbach's alpha value of 0.94 was obtained in reliability analysis. The results showed that the total women empowerment scale had an exceptional internal consistency (>9). The three domains of the scale and total woman empowerment scale had a score close to 1, indicating a high Intraclass Correlation Coefficient, and showed a high similarity between values at the second and third measurements. Self-esteem and self-efficacy subscales were the most important indicators of women's' personal empowerment. Furthermore, a highly positive correlation (p <0.01) was found between the total domains of empowerment scale. A novel women empowerment tool was developed and validated in Saudi women working as academic and administrative staff. This can serve as a reliable tool to measure women's empowerment in higher education institutions. It will eventually enable the formulation of strategies that facilitate women's empowerment and pave the path for a strong foundation for the development of the country.
Asunto(s)
Empoderamiento , Poder Psicológico , Encuestas y Cuestionarios/normas , Adulto , Análisis Factorial , Femenino , Humanos , Psicometría , Reproducibilidad de los Resultados , Arabia Saudita , AutoeficaciaRESUMEN
Hearing loss affects many people worldwide, and it hinders speech, language, and social development. Consanguineous marriage is the most prevalent social custom that leads to an increased prevalence of congenital anomalies. Premarital Counseling and Genetic Screening (PMSGC) educational program is urgently needed to empower deaf and hard hearing girls. This study aimed to investigate the effect of educational intervention based on the empowerment model on deaf and hard hearing females' self-efficacy, knowledge, and attitude toward PMSGC. A Quasi-experimental research design was conducted on 64 deaf and hard hearing female students. The data collection instrument comprised four parts: basic data and personal/family history, PMSGC quiz, Likert attitude scale, and general self-efficacy scale. Data were collected from September to December 2020. The empowerment educational intervention was conducted in four sequential phases; needs assessment, planning, implementation, and evaluation. The intervention addressed the students' knowledge, attitudes and self-efficacy. The results showed that 76.6% of the study participants had consanguineous marriage between their parents, 64.1% had a history of hereditary deafness in first-degree relatives. There were statistically significant differences between the total knowledge, attitude, and self-efficacy before and after intervention (p <0.001). In detail, 76.6% of the participants had good knowledge after the intervention compared to only 12.5% before it. Besides, 81.3% of the study participants had a positive attitude toward PMSGC before the intervention compared to 95.3% after it. Self-efficacy was low (25.0%) or moderate (75%) before the intervention compared to moderate (45.3%) or high (42.2%) after the intervention. Educational intervention based on the empowerment model significantly increased the deaf and hard hearing population's self-efficacy, knowledge, and attitude toward PMSGC. The use of the empowerment model in health education should be encouraged and taught to the medical and paramedical students.
Asunto(s)
Sordera , Asesoramiento Genético , Educación en Salud/organización & administración , Conocimientos, Actitudes y Práctica en Salud , Pérdida Auditiva , Personas con Deficiencia Auditiva/psicología , Exámenes Prenupciales , Adulto , Actitud Frente a la Salud , Sordera/diagnóstico , Sordera/genética , Empoderamiento , Femenino , Pruebas Genéticas , Pérdida Auditiva/diagnóstico , Pérdida Auditiva/genética , Humanos , Autoeficacia , Encuestas y CuestionariosRESUMEN
Women in Saudi Arabia constitute nearly 50% of the population, but their participation in economic and social activities are far below the kingdom's potential. According to the 2030 vision, women empowerment is an essential requirement for community transformation and development. The study aims to explore women empowerment among academic and administrative staff in Saudi Universities. A cross-sectional research design was conducted at 15 Saudi governmental universities. A multistage cluster sampling technique was followed to select 5587 participants. The data collection starts from April to September 2020. The current study results illustrate statistically significant differences between academic and administrative staff in the total women empowerment score and all of its dimensions (p <0.05). The majority of academic staff (84.4%) have high personal empowerment compared to 73.7% of the administrative staff. The study concluded that women empowerment is higher among academics compared to administrative staff in Saudi Universities.
Asunto(s)
Personal Administrativo/psicología , Empoderamiento , Docentes/psicología , Poder Psicológico , Mujeres Trabajadoras/psicología , Adulto , Estudios Transversales , Femenino , Humanos , Persona de Mediana Edad , Autonomía Personal , Arabia Saudita , Autoimagen , Factores Socioeconómicos , Encuestas y Cuestionarios , UniversidadesRESUMEN
The study aimed to explore the role of self-esteem and self-efficacy in women empowerment among academic and administrative staff at Saudi universities. A cross-sectional design was carried out at 15 governmental universities. A multistage cluster sampling technique was used to select 5587 participants. Multiple linear regression was used to analyze the predictive relation. Data collection included socio-demographic variables, Rosenberg self-esteem scale, general self-efficacy scale, and women empowerment scale. The results indicated that study participants' self-esteem was equally distributed between moderate (49.8%) and high (50.2%). Also, 66.9% of the participants had high self-efficacy, and 86.8% had high total women's empowerment. Regression coefficient showed that self-esteem (B=0.521, b=0.127, t=13.785 and p <0.001) and self-efficacy (B=2.388, b=0.702, t=76.049 and p <0.001) are important predictors of the total women empowerment. However, self-efficacy was observed to be the most dominant predictor (t=76.049). The total model summary shows that 73.4% of the women empowerment level can be predicted through self-esteem and self-efficacy. The study results can be used as a base to build women empowerment programs in the Kingdom of Saudi Arabia (KSA) and help to achieve the 2030 KSA vision regarding women empowerment.
Asunto(s)
Empoderamiento , Autoimagen , Autoeficacia , Adulto , Estudios Transversales , Femenino , Humanos , Arabia Saudita , Factores Socioeconómicos , Encuestas y Cuestionarios , Adulto JovenRESUMEN
Schistosomiasis is associated with human behavior in relation to water. Study of different patterns of water contact activities would help in planning strategies for control. This study aims to describe patterns of water contact activities in relation to S. mansoni infection in El-Shobak El-Sharki village in Giza governorate, in Egypt. A sample of 695 households was taken from about 127 houses. They provided stools samples and a water contact questionnaire for different activities, regions, sites, time of the day, duration of activities, patterns in different age and sex groups. Univariate and multivariate analysis of data was done. It was found that, adult males had the highest prevalence rate, then adult females while children had the least (33.5%, 27.5% and 17.4% respectively, p-value < 0.0001). Infection rate is higher in those having water contact activities, with Odds Ratio (OR) 2.01 and 95% Confidence Intervals (CI) (.94-4.24). Other significant factors are, the site of activities, time of the day and duration of contact, with p-value < 0.05. The highest score for the different patterns of activities in adult males are mainly occupational as agriculture and irrigation, their OR (95% CI) are 2.82 (.91-5.94) and 2.58 (.89-5.41), respectively. As regards females, the highest score is for domestic daily activities as washing infant clothes and utensils, their OR (95% CI) is 2.19 (.91-4.73) and 1.83 (.80-4.16) respectively. Children have the least score, their activities is mainly recreational as swimming, OR (95% CI) is 1.77 (.79-4.02). Multiple logistic regression analysis revealed that, male's activities and their longer duration are highly significant factors with prevalence as the dependant variable, OR (95% CI) is 3.07 (.73-8.19) for activities, and is 3.67 (.31-9.38) for duration. It is concluded that, human exposure pattern, in general, favors the transmission of S. mansoni. Prevalence of infection coincides with water contact activities in different age, sex and farming occupation. So, the control of S. mansoni in Egypt is not a pure medical affair. It needs multidisciplinary upgrading actions to be taken in different sectors of agriculture and irrigation reform in Egypt.
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Población Rural , Esquistosomiasis mansoni/parasitología , Esquistosomiasis/epidemiología , Agua , Adolescente , Niño , Egipto/epidemiología , Femenino , Humanos , Masculino , Encuestas y CuestionariosRESUMEN
The relationship between epidemiology of S. mansoni infection and snail distribution at a village, related to Guiza Governorate and lies south to Cairo, was investigated. A systematic random sample of houses was selected. All inhabitants of the houses were invited to share in the study. The Number examined was 704. Urine and stools were examined using Nucleopore filtration and standard Kato-Katz techniques, respectively. Snail collection was done from 35 sites along the water bodies related to the village. Snails collected were examined by cercariae shedding under light. Snail differentiation was done. The results showed that the prevalence of Schistosoma mansoni human infection was 25.1 % and GMEC was 2.4 +/- 5.5. Schistosoma haematobium infection was zero percent. Biomphlaria alexandrina snail infection rate was 3.7% with density equal 0.5 +/- 1.3. Bulinus truncatus snail infection rate was zero percent. The pattern of S. mansoni human infection was closely related to snail distribution and infection. Presence of a hybrid species of B. alexandrina and B. glabrata may explain the epidemiological pattern found in the studied village.
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Ríos , Schistosoma mansoni/parasitología , Esquistosomiasis mansoni/epidemiología , Adolescente , Adulto , Animales , Niño , Egipto/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Schistosoma mansoni/patogenicidad , Caracoles/crecimiento & desarrolloRESUMEN
BACKGROUND AND STUDY AIMS: THEBERA is a project funded by the European Union (EU), as an ERA-WIDE FP7 project, aiming to strengthen the Theodor Bilharz Research Institute (TBRI) capacities. MATERIALS AND METHODS: A SWOT (strength/weakness/opportunities/threats) analysis of human, structural and organisational existing resources was performed in light of an extensive analysis of liver disease research and clinical management in Egypt, for a full understanding of TBRI needs. RESULTS: Strength and weakness features were identified and analysed, so were actions to be implemented and targets to be accomplished, to develop a business plan gathering the required critical mass (political, scientific, industrial, social) to select investment priorities, to sacrifice non-strategic areas of research, to promote national and international connections and industrial innovations, to update diagnostics and research device technologies and clinical management processes at European levels, to implement fundraising activities, to organise and properly assess training activities for young researchers, physicians, nurses, and technicians. CONCLUSIONS: Research institute self assessment is a priority need for sustainable capacity building and for future build-up of a competent health care research institute. Sustainable capacity building strategies must be designed on needs assessment, involving salient requirements: clear strategy, leverage of administrative capacities, industrial support and connections, systematised training programmes and enhancement of mobility of health care staff implemented within ill-defined boundaries and continuously re-evaluated with multiple feedback loops in order to build a complex, adaptable and reliable system based on value.
Asunto(s)
Academias e Institutos/estadística & datos numéricos , Investigación Biomédica/organización & administración , Creación de Capacidad/organización & administración , Egipto , Política de Salud , Humanos , Desarrollo de ProgramaRESUMEN
BACKGROUND: Patient safety is a fundamental principle of healthcare; it is a new healthcare discipline that emphasizes the reporting, analysis, and prevention of medical errors that often lead to adverse healthcare events. OBJECTIVES: The aim of this study is to aid any hospital in attaining better quality of patient care in the operating room (OR) by achieving patient safety according to the WHO safety guidelines. Specific objectives include the assessment of patient safety status in OR, the identification of hazards, and the assessment of risks that jeopardize this safety. MATERIALS AND METHODS: This is a descriptive observational study carried out in three ORs of a governmental hospital. The study was carried out from December 2008 through April 2009. A total of 100 patients undergoing general surgical and urological surgical procedures were selected. The data collection tools included the WHO surgical safety checklist, nonstructured interviews, patient records, anesthesia checklist, and the risk assessment matrix. RESULTS: According to the WHO safety checklist, patients' safety was checked during three stages. During the 'sign in' stage, only 3% of all the patients had the operation site marked for surgery and an incident of a single wrong side surgery was recorded. There was a clear lack of communication between doctors and patients. During the 'time out' stage, 80% of surgeries lacked organized discussion among surgical team members for anticipated critical events. Prophylactic antibiotics were administered to 59% of patients undergoing surgeries. The 'sign out' stage was properly carried out in 100% of the procedures. Risk assessment in the 'sign in' stage showed six of 11 procedures leading to a major risk to patients. Also, in the 'time out' stage, three of eight procedures had a major risk. CONCLUSION AND RECOMMENDATIONS: To reach an optimal level of patient safety in the OR, it is recommended that the checklist should be implemented as part of the daily surgical routine. Identification of the hazards to which patients could be exposed and assessment of risks must be the ultimate goal in any OR.
Asunto(s)
Quirófanos , Seguridad del Paciente , Anestesiología , Lista de Verificación , Humanos , Errores Médicos/prevención & control , Medición de RiesgoRESUMEN
The dipstick testing, microscopic examination of urine and urine cytology were performed for inhabitants from two rural villages (El Shobak El Sharki, V.1 & El Katta, V.2) in Giza G. The proliferating cell nuclear antigen (PCNA) and Schistosoma haematobium antigen were done by immuno-histochemical stain to confirm diagnosis. Also, they were subjected to medical questionnaire, clinical examination, ultra-sonography of kidneys and urinary tract. The results showed that V.2 had higher percentage of haematuria, proteinuria, glucosuria and lower urinary tract infection than V.1. Crystaluria was higher in V.1. Sensitivity of dipstick testing compared to microscopic examination was 26.6%, & specificity was 78.7%. Lower urinary tract infection cytologically detected was 44.2% sensitivity & 62.5% specificity compared to pyuria detected by microscopic examination of urine. Among those suffering variable urinary abnormalities, schistosome antigen was not detected in any fixed urine samples in comparison to corresponding confirmed positive controls. Urine cytology detected urinary tract infection, crystaluria, dysplasia and atypia, squamous metaplasia and transitional cell carcinoma (TCC). PCNA positivity was found in TCC (100%), dysplasia (50%) and squamous metaplasia (28.6%). So, microscopic examination of urine proved valuable for tract abnormalities as pyuria, haematuria and crystaluria. Also, urine cytology is a must for malignancy of urinary tract especially in adult males.
Asunto(s)
Enfermedades Renales/diagnóstico , Schistosoma haematobium/aislamiento & purificación , Orina/citología , Orina/parasitología , Enfermedades Urológicas/diagnóstico , Adolescente , Adulto , Animales , Antígenos Helmínticos/análisis , Niño , Preescolar , Diagnóstico Diferencial , Femenino , Glucosuria , Hematuria , Humanos , Enfermedades Renales/diagnóstico por imagen , Enfermedades Renales/prevención & control , Masculino , Persona de Mediana Edad , Proteinuria , Población Rural , Schistosoma haematobium/inmunología , Sensibilidad y Especificidad , Ultrasonografía , Enfermedades Urológicas/diagnóstico por imagen , Enfermedades Urológicas/prevención & controlRESUMEN
Processing of the same stool samples was done using standard Kato-Katz (KK) technique with 41.7 mg of stools and one of the three modifications. These included KK technique using a higher concentration of glycerin (one and quarter, usual one) for preparation, or another stain (negrosin-eosin), with a specified formula, instead of the standard malachite green, or processing a smaller volume of stools (20mg). The results showed that, using cumulative infection rate from the two comparable tests as the reference, KK with higher concentration of glycerin was more sensitive than standard KK (sensitivities 77.6% and 61.2%. respectively). Using negrosin-eosin stain showed higher sensitivity (75.0%) in relation to standard KK technique (70.8%). Kato-Katz with higher concentration of glycerin showed the same sensitivity as KK with negrosin-eosin stain (85.7%) in relation to others. All comparisons showed statistically insignificant differences ((P>0.5). Using 20 mg of stools showed very low sensitivity in relation to standard KK technique (57.9% & 100.0% respectively). The statistical difference was highly significant. All specificities were 100%. Other screening indices showed the same trend of sensitivities. Degree of microscope clarity was optimal with higher concentration of glycerin. Negrosin-eosin showed better visualization of ova than the standard KK. All modifications took only an hour after processing to be examined. KK technique used with any of these modifications, is simple, inexpensive. use of either a higher concentration of glycerin or negrosin-eosin stain and recommended for both field studies and primary health care settings.