Detalles de la búsqueda
1.
Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9.
J Biol Chem;
297(3): 101018, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34331944
2.
Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase.
J Antimicrob Chemother;
77(9): 2441-2447, 2022 08 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35770844
3.
Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Bioorg Med Chem;
45: 116315, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34364222
4.
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists.
J Biol Chem;
294(10): 3720-3734, 2019 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30598509
5.
NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide-dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei.
J Biomol NMR;
74(10-11): 595-611, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32761504
6.
Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J Biol Chem;
293(43): 16559-16571, 2018 10 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30181210
7.
The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors.
Molecules;
24(20)2019 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31635355
8.
Controlled Construction of Cyclic dâ /â l Peptide Nanorods.
Angew Chem Int Ed Engl;
58(2): 596-601, 2019 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30452108
9.
Dietary docosahexaenoic acid supplementation enhances expression of fatty acid-binding protein 5 at the blood-brain barrier and brain docosahexaenoic acid levels.
J Neurochem;
146(2): 186-197, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29582413
10.
Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets.
J Neurochem;
144(1): 81-92, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29105065
11.
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function.
J Neurosci;
36(46): 11755-11767, 2016 11 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27852782
12.
The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity.
Org Biomol Chem;
15(34): 7173-7180, 2017 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28812779
13.
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death.
Proc Natl Acad Sci U S A;
111(42): 15072-7, 2014 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25288762
14.
Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner.
J Biol Chem;
290(22): 13895-906, 2015 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-25847235
15.
Binding of CFA/I Pili of Enterotoxigenic Escherichia coli to Asialo-GM1 Is Mediated by the Minor Pilin CfaE.
Infect Immun;
84(5): 1642-1649, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26975993
16.
Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data.
J Biomol NMR;
66(3): 195-208, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27778134
17.
Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.
J Mol Recognit;
29(6): 281-91, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26804042
18.
Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents.
Molecules;
21(7)2016 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27438817
19.
Structure of the chicken CD3εδ/γ heterodimer and its assembly with the αßT cell receptor.
J Biol Chem;
289(12): 8240-51, 2014 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24488493
20.
Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.
Acta Crystallogr D Biol Crystallogr;
71(Pt 12): 2386-95, 2015 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26627647