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1.
Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides.
J Biol Chem;
285(18): 13498-506, 2010 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-20167598
2.
Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase.
Bioorg Med Chem Lett;
21(13): 4059-65, 2011 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21640588
3.
A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation.
J Pharmacol Exp Ther;
333(3): 797-807, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20237073
4.
Expression, purification, characterization and crystallization of non- and phosphorylated states of JAK2 and JAK3 kinase domain.
Protein Expr Purif;
69(1): 54-63, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19781647
5.
Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804.
Biochemistry;
48(27): 6402-11, 2009 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19496616
6.
A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal models.
J Pharmacol Exp Ther;
329(1): 14-25, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19168710
7.
Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translation.
J Pharmacol Exp Ther;
331(3): 882-95, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19720877
8.
Novel tight-binding inhibitory factor-kappaB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation.
J Pharmacol Exp Ther;
330(2): 377-88, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19478133
9.
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
J Med Chem;
50(11): 2647-54, 2007 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-17480064
10.
Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2.
Biochim Biophys Acta;
1598(1-2): 88-97, 2002 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-12147348
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