Aldrin and dieldrin: loss under sterile conditions.

After their application to sterile nutrient agar, both aldrin and dieldrin disappeared rather rapidly from the agar in glass-covered petri dishes. In most instances this disappearance was considerably retarded from agar inoculated with either fungi or bacteria. In the presence of microorganisms, aldrin was also epoxidized into dieldrin. Half of the applied aldrin volatilized from the agar during the first day of incubation; dieldrin volatilized more slowly and at a constant rate.

Endogenous nitrate synthesis in selected infectious diseases and ulcerative colitis.

Investigations into acute and chronic diarrheal patients confirmed the results of animal experiments on the role of cytotoxic activated macrophages in endogenous formation of nitrates. Because a number of inflammatory diseases did not cause a nitrate release in urine, blood, and saliva, the general importance of nitrates to characterize the initiation and course of inflammations must be questioned.

[Nitrate and nitrite content of the saliva, urine, blood and cerebrospinal fluid in patients at an infection clinic]. / Nitrat- und Nitritgehalt in Speichel, Urin, Blut und Liquor von Patienten einer Infektionsklinik.

In 254 patients of a ward for infectious diseases the authors demonstrated that inflammatory diseases are frequently accompanied by an increase in nitrate content of the blood, urine and saliva. This effect is especially evident in gastrointestinal disorders. Correlations of nitrate with indicators of the inflammatory process are, if at all, very weak. The endogenous synthesis of nitrate may be of importance for the total nitrate load to the organism especially in children or patients with long-lasting inflammatory disease.

[Liver diseases and pregnancy]. / Lebererkrankungen und Schwangerschaft.

221 from 161,674 pregnant women had been hospitalized because of suspicion of virus hepatitis. That is a frequency of 1.4%o. Confirmation of diagnosis was made by histology in 18.5 per cent. The rate of low birth weight infants of 24.2 per cent and the frequency of 13.4 per cent of obstetric operations refer for a diminished placental function. Questions of diagnostics and the course of pregnancy in the combination of liver diseases and pregnancy are discussed.

[Clinical aspects of Toxoplasma primary infection in pregnancy]. / Klinische Gesichtspunkte der Toxoplasma-Primoinfektion in der Schwangerschaft.

Prevention of connatal toxoplasmosis is only possible by early diagnosis and treatment of toxoplasma-primoinfection in pregnancy. The authors describe the diagnostic approach and report on 110 pregnant women with toxoplasma-primoinfection. Treatment consisted in the application of pyrimethamine in combination with a sulfonamide or spiramycine. Side-effects of pyrimethamine are mentioned. The aim is an improvement of diagnosis and therapy.

[Current aspects of giardiasis]. / Aktuelle Aspekte der Giardiose.

Modern epidemiological, clinical, diagnostic and therapeutic aspects of giardiasis are described.

[Results of clinical and epidemiologic studies of the nitrate problem]. / Ergebnisse klinischer und epidemiologischer Untersuchungen zum Nitratproblem.

Small differences in nitrate intake with the drinking water are not reflected in nitrate contents of saliva and urine of test persons. A correlation of nitrate concentration in body fluids and cancer incidence can be expected hardly. Inflammatory diseases of the gut are frequently accompanied by enhanced endogenous nitrate synthesis and have an essential influence on total nitrate load of the human organism. Nitrate contents in saliva and/or urine are not general indicators of inflammatory processes. As the role of the nitrate ion in humans is not yet understood, the claim remains for a nitrate intake being as low as possible.