Detalles de la búsqueda
1.
Effects of Repeated Treatment with the Monoacylglycerol Lipase Inhibitor MJN110 on Pain-Related Depression of Nesting and Cannabinoid 1 Receptor Function in Male and Female Mice.
J Pharmacol Exp Ther;
2024 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38262742
2.
Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers.
Bioorg Chem;
120: 105641, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35093692
3.
A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists.
Molecules;
27(19)2022 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36234992
4.
Exploring naltrexamine derivatives featuring azaindole moiety via nitrogen-walk approach to investigate their in vitro pharmacological profiles at the mu opioid receptor.
Bioorg Med Chem Lett;
41: 127953, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33766769
5.
Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4,5α-epoxy-3,14ß-dihydroxy-6ß-[(4'-pyridyl) carboxamido]morphinan derivatives via their binding affinity and selectivity profiles on opioid receptors.
Bioorg Chem;
109: 104702, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33631465
6.
Differential Tolerance to FTY720-Induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of Sphingosine-1-Phosphate Receptor Adaptation.
J Pharmacol Exp Ther;
366(3): 509-518, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29945931
7.
Cannabinoid Receptor Interacting Protein 1a Competition with ß-Arrestin for CB1 Receptor Binding Sites.
Mol Pharmacol;
91(2): 75-86, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27895162
8.
Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner.
J Neurochem;
139(3): 396-407, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27513693
9.
Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and ß-arrestin 2 activity in the forebrain.
Neurobiol Dis;
92(Pt B): 124-36, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26845176
10.
Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice.
J Pharmacol Exp Ther;
358(2): 306-14, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27307500
11.
Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D2 and D3 Receptors.
Neurochem Res;
41(1-2): 328-339, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26718829
12.
Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization.
Bioorg Med Chem;
24(22): 5969-5987, 2016 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27720326
13.
Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice.
J Neurosci;
34(15): 5152-63, 2014 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24719095
14.
Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation.
Mol Pharmacol;
87(4): 747-65, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25657338
15.
Role of Dopamine Type 1 Receptors and Dopamine- and cAMP-Regulated Phosphoprotein Mr 32 kDa in Δ9-Tetrahydrocannabinol-Mediated Induction of ΔFosB in the Mouse Forebrain.
J Pharmacol Exp Ther;
354(3): 316-27, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26099530
16.
Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice.
J Pharmacol Exp Ther;
354(2): 111-20, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25998048
17.
Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14ß-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands.
Bioorg Med Chem;
23(8): 1701-15, 2015 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25783191
18.
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells.
J Pharmacol Exp Ther;
348(2): 293-302, 2014 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-24259678
19.
Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice.
J Pharmacol Exp Ther;
350(2): 196-204, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24849924
20.
Predicting the molecular interactions of CRIP1a-cannabinoid 1 receptor with integrated molecular modeling approaches.
Bioorg Med Chem Lett;
24(4): 1158-65, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24461351