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1.

Pathogenesis of human B cell lymphomas.

Shaffer, Arthur L; Young, Ryan M; Staudt, Louis M.

Annu Rev Immunol; 30: 565-610, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22224767

2.

A multiprotein supercomplex controlling oncogenic signalling in lymphoma.

Phelan, James D; Young, Ryan M; Webster, Daniel E; Roulland, Sandrine; Wright, George W; Kasbekar, Monica; Shaffer, Arthur L; Ceribelli, Michele; Wang, James Q; Schmitz, Roland; Nakagawa, Masao; Bachy, Emmanuel; Huang, Da Wei; Ji, Yanlong; Chen, Lu; Yang, Yandan; Zhao, Hong; Yu, Xin; Xu, Weihong; Palisoc, Maryknoll M; Valadez, Racquel R; Davies-Hill, Theresa; Wilson, Wyndham H; Chan, Wing C; Jaffe, Elaine S; Gascoyne, Randy D; Campo, Elias; Rosenwald, Andreas; Ott, German; Delabie, Jan; Rimsza, Lisa M; Rodriguez, Fausto J; Estephan, Fayez; Holdhoff, Matthias; Kruhlak, Michael J; Hewitt, Stephen M; Thomas, Craig J; Pittaluga, Stefania; Oellerich, Thomas; Staudt, Louis M.

Nature; 560(7718): 387-391, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-29925955

3.

Regulation of B cell receptor-dependent NF-κB signaling by the tumor suppressor KLHL14.

Choi, Jaewoo; Phelan, James D; Wright, George W; Häupl, Björn; Huang, Da Wei; Shaffer, Arthur L; Young, Ryan M; Wang, Zhuo; Zhao, Hong; Yu, Xin; Oellerich, Thomas; Staudt, Louis M.

Proc Natl Acad Sci U S A; 117(11): 6092-6102, 2020 03 17.

Artículo en Inglés | MEDLINE | ID: mdl-32127472

4.

Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A.

Fish, Kamonwan; Comoglio, Federico; Shaffer, Arthur L; Ji, Yanlong; Pan, Kuan-Ting; Scheich, Sebastian; Oellerich, Angelika; Doebele, Carmen; Ikeda, Masato; Schaller, Samantha J; Nguyen, Hang; Muppidi, Jagan; Wright, George W; Urlaub, Henning; Serve, Hubert; Staudt, Louis M; Longnecker, Richard; Oellerich, Thomas.

Proc Natl Acad Sci U S A; 117(42): 26318-26327, 2020 10 20.

Artículo en Inglés | MEDLINE | ID: mdl-33020271

5.

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma.

Schmitz, Roland; Wright, George W; Huang, Da Wei; Johnson, Calvin A; Phelan, James D; Wang, James Q; Roulland, Sandrine; Kasbekar, Monica; Young, Ryan M; Shaffer, Arthur L; Hodson, Daniel J; Xiao, Wenming; Yu, Xin; Yang, Yandan; Zhao, Hong; Xu, Weihong; Liu, Xuelu; Zhou, Bin; Du, Wei; Chan, Wing C; Jaffe, Elaine S; Gascoyne, Randy D; Connors, Joseph M; Campo, Elias; Lopez-Guillermo, Armando; Rosenwald, Andreas; Ott, German; Delabie, Jan; Rimsza, Lisa M; Tay Kuang Wei, Kevin; Zelenetz, Andrew D; Leonard, John P; Bartlett, Nancy L; Tran, Bao; Shetty, Jyoti; Zhao, Yongmei; Soppet, Dan R; Pittaluga, Stefania; Wilson, Wyndham H; Staudt, Louis M.

N Engl J Med; 378(15): 1396-1407, 2018 04 12.

Artículo en Inglés | MEDLINE | ID: mdl-29641966

6.

Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.

Valdez, Patricia A; Vithayathil, Paul J; Janelsins, Brian M; Shaffer, Arthur L; Williamson, Peter R; Datta, Sandip K.

Immunity; 36(4): 668-79, 2012 Apr 20.

Artículo en Inglés | MEDLINE | ID: mdl-22464170

7.

The case of the missing c-Myc.

Shaffer, Arthur L; Staudt, Louis M.

Nat Immunol; 13(11): 1029-31, 2012 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-23080195

8.

Subtype-specific addiction of the activated B-cell subset of diffuse large B-cell lymphoma to FOXP1.

Dekker, Joseph D; Park, Daechan; Shaffer, Arthur L; Kohlhammer, Holger; Deng, Wei; Lee, Bum-Kyu; Ippolito, Gregory C; Georgiou, George; Iyer, Vishwanath R; Staudt, Louis M; Tucker, Haley O.

Proc Natl Acad Sci U S A; 113(5): E577-86, 2016 Feb 02.

Artículo en Inglés | MEDLINE | ID: mdl-26787899

9.

Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma.

Rui, Lixin; Drennan, Amanda C; Ceribelli, Michele; Zhu, Fen; Wright, George W; Huang, Da Wei; Xiao, Wenming; Li, Yangguang; Grindle, Kreg M; Lu, Li; Hodson, Daniel J; Shaffer, Arthur L; Zhao, Hong; Xu, Weihong; Yang, Yandan; Staudt, Louis M.

Proc Natl Acad Sci U S A; 113(46): E7260-E7267, 2016 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-27799566

10.

Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2.

Hodson, Daniel J; Shaffer, Arthur L; Xiao, Wenming; Wright, George W; Schmitz, Roland; Phelan, James D; Yang, Yandan; Webster, Daniel E; Rui, Lixin; Kohlhammer, Holger; Nakagawa, Masao; Waldmann, Thomas A; Staudt, Louis M.

Proc Natl Acad Sci U S A; 113(14): E2039-46, 2016 Apr 05.

Artículo en Inglés | MEDLINE | ID: mdl-26993806

11.

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics.

Schmitz, Roland; Young, Ryan M; Ceribelli, Michele; Jhavar, Sameer; Xiao, Wenming; Zhang, Meili; Wright, George; Shaffer, Arthur L; Hodson, Daniel J; Buras, Eric; Liu, Xuelu; Powell, John; Yang, Yandan; Xu, Weihong; Zhao, Hong; Kohlhammer, Holger; Rosenwald, Andreas; Kluin, Philip; Müller-Hermelink, Hans Konrad; Ott, German; Gascoyne, Randy D; Connors, Joseph M; Rimsza, Lisa M; Campo, Elias; Jaffe, Elaine S; Delabie, Jan; Smeland, Erlend B; Ogwang, Martin D; Reynolds, Steven J; Fisher, Richard I; Braziel, Rita M; Tubbs, Raymond R; Cook, James R; Weisenburger, Dennis D; Chan, Wing C; Pittaluga, Stefania; Wilson, Wyndham; Waldmann, Thomas A; Rowe, Martin; Mbulaiteye, Sam M; Rickinson, Alan B; Staudt, Louis M.

Nature; 490(7418): 116-20, 2012 Oct 04.

Artículo en Inglés | MEDLINE | ID: mdl-22885699

12.

ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans.

Hathcock, Karen S; Padilla-Nash, Hesed M; Camps, Jordi; Shin, Dong-Mi; Triner, Daniel; Shaffer, Arthur L; Maul, Robert W; Steinberg, Seth M; Gearhart, Patricia J; Staudt, Louis M; Morse, Herbert C; Ried, Thomas; Hodes, Richard J.

Blood; 126(20): 2291-301, 2015 Nov 12.

Artículo en Inglés | MEDLINE | ID: mdl-26400962

13.

Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.

Nündel, Kerstin; Green, Nathaniel M; Shaffer, Arthur L; Moody, Krishna L; Busto, Patricia; Eilat, Dan; Miyake, Kensuke; Oropallo, Michael A; Cancro, Michael P; Marshak-Rothstein, Ann.

J Immunol; 194(6): 2504-12, 2015 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-25681333

14.

Oncogenically active MYD88 mutations in human lymphoma.

Ngo, Vu N; Young, Ryan M; Schmitz, Roland; Jhavar, Sameer; Xiao, Wenming; Lim, Kian-Huat; Kohlhammer, Holger; Xu, Weihong; Yang, Yandan; Zhao, Hong; Shaffer, Arthur L; Romesser, Paul; Wright, George; Powell, John; Rosenwald, Andreas; Muller-Hermelink, Hans Konrad; Ott, German; Gascoyne, Randy D; Connors, Joseph M; Rimsza, Lisa M; Campo, Elias; Jaffe, Elaine S; Delabie, Jan; Smeland, Erlend B; Fisher, Richard I; Braziel, Rita M; Tubbs, Raymond R; Cook, J R; Weisenburger, Denny D; Chan, Wing C; Staudt, Louis M.

Nature; 470(7332): 115-9, 2011 Feb 03.

Artículo en Inglés | MEDLINE | ID: mdl-21179087

15.

Dendritic cell fate is determined by BCL11A.

Ippolito, Gregory C; Dekker, Joseph D; Wang, Yui-Hsi; Lee, Bum-Kyu; Shaffer, Arthur L; Lin, Jian; Wall, Jason K; Lee, Baeck-Seung; Staudt, Louis M; Liu, Yong-Jun; Iyer, Vishwanath R; Tucker, Haley O.

Proc Natl Acad Sci U S A; 111(11): E998-1006, 2014 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-24591644

16.

Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.

Ceribelli, Michele; Kelly, Priscilla N; Shaffer, Arthur L; Wright, George W; Xiao, Wenming; Yang, Yibin; Mathews Griner, Lesley A; Guha, Rajarshi; Shinn, Paul; Keller, Jonathan M; Liu, Dongbo; Patel, Paresma R; Ferrer, Marc; Joshi, Shivangi; Nerle, Sujata; Sandy, Peter; Normant, Emmanuel; Thomas, Craig J; Staudt, Louis M.

Proc Natl Acad Sci U S A; 111(31): 11365-70, 2014 Aug 05.

Artículo en Inglés | MEDLINE | ID: mdl-25049379

17.

B cells are not essential for Lactobacillus-mediated protection against lethal pneumovirus infection.

Percopo, Caroline M; Dyer, Kimberly D; Garcia-Crespo, Katia E; Gabryszewski, Stanislaw J; Shaffer, Arthur L; Domachowske, Joseph B; Rosenberg, Helene F.

J Immunol; 192(11): 5265-72, 2014 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-24748495

18.

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.

Davis, R Eric; Ngo, Vu N; Lenz, Georg; Tolar, Pavel; Young, Ryan M; Romesser, Paul B; Kohlhammer, Holger; Lamy, Laurence; Zhao, Hong; Yang, Yandan; Xu, Weihong; Shaffer, Arthur L; Wright, George; Xiao, Wenming; Powell, John; Jiang, Jian-Kang; Thomas, Craig J; Rosenwald, Andreas; Ott, German; Muller-Hermelink, Hans Konrad; Gascoyne, Randy D; Connors, Joseph M; Johnson, Nathalie A; Rimsza, Lisa M; Campo, Elias; Jaffe, Elaine S; Wilson, Wyndham H; Delabie, Jan; Smeland, Erlend B; Fisher, Richard I; Braziel, Rita M; Tubbs, Raymond R; Cook, J R; Weisenburger, Dennis D; Chan, Wing C; Pierce, Susan K; Staudt, Louis M.

Nature; 463(7277): 88-92, 2010 Jan 07.

Artículo en Inglés | MEDLINE | ID: mdl-20054396

19.

Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4.

Huang, Xiangao; Di Liberto, Maurizio; Jayabalan, David; Liang, Jun; Ely, Scott; Bretz, Jamieson; Shaffer, Arthur L; Louie, Tracey; Chen, Isan; Randolph, Sophia; Hahn, William C; Staudt, Louis M; Niesvizky, Ruben; Moore, Malcolm A S; Chen-Kiang, Selina.

Blood; 120(5): 1095-106, 2012 Aug 02.

Artículo en Inglés | MEDLINE | ID: mdl-22718837

20.

IRF4 addiction in multiple myeloma.

Shaffer, Arthur L; Emre, N C Tolga; Lamy, Laurence; Ngo, Vu N; Wright, George; Xiao, Wenming; Powell, John; Dave, Sandeep; Yu, Xin; Zhao, Hong; Zeng, Yuxin; Chen, Bangzheng; Epstein, Joshua; Staudt, Louis M.

Nature; 454(7201): 226-31, 2008 Jul 10.

Artículo en Inglés | MEDLINE | ID: mdl-18568025

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