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1.

In vivo enrichment of genetically manipulated platelets for murine hemophilia B gene therapy.

Chen, Yingyu; Schroeder, Jocelyn A; Gao, Chunyan; Li, Jing; Hu, Jianda; Shi, Qizhen.

J Cell Physiol; 236(1): 354-365, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32510630

2.

Blocking hemophilic arthropathy.

Shi, Qizhen; Weiler, Hartmut.

Blood; 139(18): 2734-2735, 2022 05 05.

Artículo en Inglés | MEDLINE | ID: mdl-35511191

3.

The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity.

Chen, Yingyu; Schroeder, Jocelyn A; Chen, Juan; Luo, Xiaofeng; Baumgartner, Christina K; Montgomery, Robert R; Hu, Jianda; Shi, Qizhen.

Blood; 127(10): 1346-54, 2016 Mar 10.

Artículo en Inglés | MEDLINE | ID: mdl-26668132

4.

A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII.

Fahs, Scot A; Hille, Matthew T; Shi, Qizhen; Weiler, Hartmut; Montgomery, Robert R.

Blood; 123(24): 3706-13, 2014 Jun 12.

Artículo en Inglés | MEDLINE | ID: mdl-24705491

5.

Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells.

Shi, Qizhen; Kuether, Erin L; Chen, Yingyu; Schroeder, Jocelyn A; Fahs, Scot A; Montgomery, Robert R.

Blood; 123(3): 395-403, 2014 Jan 16.

Artículo en Inglés | MEDLINE | ID: mdl-24269957

6.

In vivo generated hematopoietic stem cells from genome edited induced pluripotent stem cells are functional in platelet-targeted gene therapy of murine hemophilia A.

Wang, Dawei; Zhang, Guowei; Gu, Junjie; Shao, Xiaohu; Dai, Yuting; Li, Jianfeng; Pan, Xiaohong; Yao, Shuxian; Xu, Aining; Jin, Ying; Huang, Jinyan; Shi, Qizhen; Zhu, Jiang; Xi, Xiaodong; Chen, Zhu; Chen, Saijuan.

Haematologica; 105(4): e175-e179, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31296582

7.

Platelet gene therapy by lentiviral gene delivery to hematopoietic stem cells restores hemostasis and induces humoral immune tolerance in FIX(null) mice.

Chen, Yingyu; Schroeder, Jocelyn A; Kuether, Erin L; Zhang, Guowei; Shi, Qizhen.

Mol Ther; 22(1): 169-77, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-24042561

8.

Platelet-targeted gene therapy induces immune tolerance in hemophilia and beyond.

Kumar, Saurabh; Schroeder, Jocelyn A; Shi, Qizhen.

J Thromb Haemost; 22(1): 23-34, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-37558132

9.

Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.

Strilchuk, Amy W; Hur, Woosuk S; Batty, Paul; Sang, Yaqiu; Abrahams, Sara R; Yong, Alyssa S M; Leung, Jerry; Silva, Lakmali M; Schroeder, Jocelyn A; Nesbitt, Kate; de Laat, Bas; Moutsopoulos, Niki M; Bugge, Thomas H; Shi, Qizhen; Cullis, Pieter R; Merricks, Elizabeth P; Wolberg, Alisa S; Flick, Matthew J; Lillicrap, David; Nichols, Timothy C; Kastrup, Christian J.

Sci Transl Med; 16(735): eadh0027, 2024 Feb 21.

Artículo en Inglés | MEDLINE | ID: mdl-38381848

10.

Solvent or temperature induced diverse coordination polymers of silver(I) sulfate and bipyrazole systems: syntheses, crystal structures, luminescence, and sorption properties.

Du, Li-Yun; Shi, Wen-Juan; Hou, Lei; Wang, Yao-Yu; Shi, Qi-Zhen; Zhu, Zhonghua.

Inorg Chem; 52(24): 14018-27, 2013 Dec 16.

Artículo en Inglés | MEDLINE | ID: mdl-24295278

11.

Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy.

Kanaji, Sachiko; Kuether, Erin L; Fahs, Scot A; Schroeder, Jocelyn A; Ware, Jerry; Montgomery, Robert R; Shi, Qizhen.

Mol Ther; 20(3): 625-32, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22044935

12.

Pre-existing anti-factor VIII immunity alters therapeutic platelet-targeted factor VIII engraftment following busulfan conditioning through cytotoxic CD8 T cells.

Jing, Weiqing; Baumgartner, Christina K; Xue, Feng; Schroeder, Jocelyn A; Shi, Qizhen.

J Thromb Haemost; 21(3): 488-498, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36696197

13.

PACSIN2 regulates platelet integrin ß1 hemostatic function.

Biswas, Ratnashree; Boyd, Emily K; Eaton, Nathan; Steenackers, Agata; Schulte, Marie L; Reusswig, Friedrich; Yu, Hongyin; Drew, Caleb; Kahr, Walter H A; Shi, Qizhen; Plomann, Markus; Hoffmeister, Karin M; Falet, Hervé.

J Thromb Haemost; 21(12): 3619-3632, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-37678551

14.

Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression.

Li, June; Karakas, Danielle; Xue, Feng; Chen, Yingyu; Zhu, Guangheng; Yucel, Yeni H; MacParland, Sonya A; Zhang, Haibo; Semple, John W; Freedman, John; Shi, Qizhen; Ni, Heyu.

Research (Wash D C); 6: 0236, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37808178

15.

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A.

Shi, Qizhen; Fahs, Scot A; Kuether, Erin L; Cooley, Brian C; Weiler, Hartmut; Montgomery, Robert R.

Blood; 116(16): 3049-57, 2010 Oct 21.

Artículo en Inglés | MEDLINE | ID: mdl-20606161

16.

Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice.

Zhang, Guowei; Shi, Qizhen; Fahs, Scot A; Kuether, Erin L; Walsh, Christopher E; Montgomery, Robert R.

Blood; 116(8): 1235-43, 2010 Aug 26.

Artículo en Inglés | MEDLINE | ID: mdl-20445020

17.

Hemophilia a patients with inhibitors: Mechanistic insights and novel therapeutic implications.

Luo, Liping; Zheng, Qiaoyun; Chen, Zhenyu; Huang, Meijuan; Fu, Lin; Hu, Jianda; Shi, Qizhen; Chen, Yingyu.

Front Immunol; 13: 1019275, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36569839

18.

Targeting transmembrane-domain-less MOG expression to platelets prevents disease development in experimental autoimmune encephalomyelitis.

Cai, Yuanhua; Schroeder, Jocelyn A; Jing, Weiqing; Gurski, Cody; Williams, Calvin B; Wang, Shaoyuan; Dittel, Bonnie N; Shi, Qizhen.

Front Immunol; 13: 1029356, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36389708

19.

Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia.

Chen, Yuwen; Luo, Liping; Zheng, Yongzhi; Zheng, Qiaoyun; Zhang, Na; Gan, Donghui; Yirga, Shimuye Kalayu; Lin, Zhenxing; Shi, Qizhen; Fu, Lin; Hu, Jianda; Chen, Yingyu.

Front Immunol; 13: 810620, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35450072

20.

A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD.

Shi, Qizhen; Fahs, Scot A; Mattson, Jeremy G; Yu, Hongyin; Perry, Crystal L; Morateck, Patricia A; Schroeder, Jocelyn A; Rapten, Jessica; Weiler, Hartmut; Montgomery, Robert R.

Blood Adv; 6(9): 2778-2790, 2022 05 10.

Artículo en Inglés | MEDLINE | ID: mdl-35015821

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