Air quality status in Greater Thessaloniki Area and the emission reductions needed for attaining the EU air quality legislation.

This paper aims at imprinting the urban air quality status and assessing the impact of various emission reduction scenarios on the photochemical and particulate matter air pollution levels in the Greater Thessaloniki Area, Greece. In particular, it is investigated under which conditions compliance with the EU air quality legislation can be achieved. For this purpose, the Ozone Fine Structure model is applied for a full calendar period (reference year 2002), as well as for specific scenarios, corresponding to predefined emission reductions for 2010. The model results for photochemical and particulate matter air pollution levels in 2002 agree fairly well with the observations. Predictions for 2010 indicate that significant improvement towards the EU legislation requirements can be achieved for certain emission reduction scenarios. However, an overall strategy will also have to include additional local scale measures.

[Frontotemporal dementia: neurotransmitter and clinical symptoms with focus on therapeutic targets]. / Frontotemporale Demenz: Neurotransmitter und klinische Symptomatik im Fokus therapeutischer Uberlegungen.

Frontotemporal dementia is more frequently diagnosed because of revised diagnostic procedures. Due to the lack of pharmacological trials it is a disease that is difficult to manage in the way of evidence based medicine. Deficits in serotonergic and dopaminergic signal-transmission are well known. The cholinergic system does not seem to be affected. Case reports and clinical trials show a benefit by using antidepressants, neuroleptics and mood stabilizers. Nevertheless only paroxetine, trazodone and rivastigmine are tested by double-blind, placebo-controlled studies. While paroxetine shows inconsistent data, trazodone improves behavioural symptoms. Patients report a treatment-emergent adverse effect including fatigue, dizziness and hypotension. Rivastigmine leads to a significant decrease in the Neuropsychiatric Inventory Score. Finally, we present a two-cases-report that shows improve of disease symptoms under treatment with repetitive transcranial magnet stimulation.

Decision support system for the evaluation of urban air pollution control options: application for particulate pollution in Thessaloniki, Greece.

Development of strategies to control urban air pollution is a complex and multi-disciplinary process involving a wide range of scientists with different expertise and interests. This paper presents an integrated assessment methodological scheme for the evaluation of air pollution control measures that are put forward in order to reduce sufficiently air pollution levels in urban areas. Forming long-term, efficient air pollution control strategies requires knowledge of the costs associated with their implementation, the emission inventories and emission reductions to be achieved, as well as the concentration variations that represent air quality levels in the area examined. In contrast to the majority of the currently employed assessment approaches, the presented scheme enables the evaluation of any proposed air pollution control option in terms of its combined impact on air quality and social welfare, by correlating economic and health impact assessment issues. The approach presented in this paper brings together air quality modelling and mathematical programming techniques and provides a decision support system for the determination of optimal bundles of air pollution control options according to the particular features and needs of the areas examined. Both cost-effectiveness and cost-benefit approaches are taken into account in order to put the problem on the basis of economic efficiency from a societal perspective. The methodology is implemented for the case of Thessaloniki, Greece, which is selected on the grounds that the area is considered as one of the most polluted--if not the most polluted--cities within Europe, especially with respect to airborne particles.