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1.

The Walrus and the Carpenter: Complex Regulation of Tumor Immunity in Colorectal Cancer.

Dewson, Grant; Silke, John.

Cell; 174(1): 14-16, 2018 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-29958104

2.

Interferon-Î³ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.

Simpson, Daniel S; Pang, Jiyi; Weir, Ashley; Kong, Isabella Y; Fritsch, Melanie; Rashidi, Maryam; Cooney, James P; Davidson, Kathryn C; Speir, Mary; Djajawi, Tirta M; Hughes, Sebastian; Mackiewicz, Liana; Dayton, Merle; Anderton, Holly; Doerflinger, Marcel; Deng, Yexuan; Huang, Allan Shuai; Conos, Stephanie A; Tye, Hazel; Chow, Seong H; Rahman, Arfatur; Norton, Raymond S; Naderer, Thomas; Nicholson, Sandra E; Burgio, Gaetan; Man, Si Ming; Groom, Joanna R; Herold, Marco J; Hawkins, Edwin D; Lawlor, Kate E; Strasser, Andreas; Silke, John; Pellegrini, Marc; Kashkar, Hamid; Feltham, Rebecca; Vince, James E.

Immunity; 55(3): 423-441.e9, 2022 03 08.

Artículo en Inglés | MEDLINE | ID: mdl-35139355

3.

Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival.

Johnston, Amelia J; Murphy, Kate T; Jenkinson, Laura; Laine, David; Emmrich, Kerstin; Faou, Pierre; Weston, Ross; Jayatilleke, Krishnath M; Schloegel, Jessie; Talbo, Gert; Casey, Joanne L; Levina, Vita; Wong, W Wei-Lynn; Dillon, Helen; Sahay, Tushar; Hoogenraad, Joan; Anderton, Holly; Hall, Cathrine; Schneider, Pascal; Tanzer, Maria; Foley, Michael; Scott, Andrew M; Gregorevic, Paul; Liu, Spring Yingchun; Burkly, Linda C; Lynch, Gordon S; Silke, John; Hoogenraad, Nicholas J.

Cell; 162(6): 1365-78, 2015 Sep 10.

Artículo en Inglés | MEDLINE | ID: mdl-26359988

4.

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

Rickard, James A; O'Donnell, Joanne A; Evans, Joseph M; Lalaoui, Najoua; Poh, Ashleigh R; Rogers, TeWhiti; Vince, James E; Lawlor, Kate E; Ninnis, Robert L; Anderton, Holly; Hall, Cathrine; Spall, Sukhdeep K; Phesse, Toby J; Abud, Helen E; Cengia, Louise H; Corbin, Jason; Mifsud, Sandra; Di Rago, Ladina; Metcalf, Donald; Ernst, Matthias; Dewson, Grant; Roberts, Andrew W; Alexander, Warren S; Murphy, James M; Ekert, Paul G; Masters, Seth L; Vaux, David L; Croker, Ben A; Gerlic, Motti; Silke, John.

Cell; 157(5): 1175-88, 2014 May 22.

Artículo en Inglés | MEDLINE | ID: mdl-24813849

5.

cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation.

Schorn, Fabian; Werthenbach, J Paul; Hoffmann, Mattes; Daoud, Mila; Stachelscheid, Johanna; Schiffmann, Lars M; Hildebrandt, Ximena; Lyu, Su Ir; Peltzer, Nieves; Quaas, Alexander; Vucic, Domagoj; Silke, John; Pasparakis, Manolis; Kashkar, Hamid.

EMBO J; 42(22): e113614, 2023 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-37789765

6.

Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1ß release in X-linked inhibitor of apoptosis (XIAP) deficiency.

Hughes, Sebastian A; Lin, Meng; Weir, Ashley; Huang, Bing; Xiong, Liya; Chua, Ngee Kiat; Pang, Jiyi; Santavanond, Jascinta P; Tixeira, Rochelle; Doerflinger, Marcel; Deng, Yexuan; Yu, Chien-Hsiung; Silke, Natasha; Conos, Stephanie A; Frank, Daniel; Simpson, Daniel S; Murphy, James M; Lawlor, Kate E; Pearson, Jaclyn S; Silke, John; Pellegrini, Marc; Herold, Marco J; Poon, Ivan K H; Masters, Seth L; Li, Mingsong; Tang, Qin; Zhang, Yuxia; Rashidi, Maryam; Geng, Lanlan; Vince, James E.

EMBO J; 42(5): e110468, 2023 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-36647737

7.

The diverse role of RIP kinases in necroptosis and inflammation.

Silke, John; Rickard, James A; Gerlic, Motti.

Nat Immunol; 16(7): 689-97, 2015 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-26086143

8.

RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.

Liccardi, Gianmaria; Ramos Garcia, Laura; Tenev, Tencho; Annibaldi, Alessandro; Legrand, Arnaud J; Robertson, David; Feltham, Rebecca; Anderton, Holly; Darding, Maurice; Peltzer, Nieves; Dannappel, Marius; Schünke, Hannah; Fava, Luca L; Haschka, Manuel D; Glatter, Timo; Nesvizhskii, Alexey; Schmidt, Alexander; Harris, Philip A; Bertin, John; Gough, Peter J; Villunger, Andreas; Silke, John; Pasparakis, Manolis; Bianchi, Katiuscia; Meier, Pascal.

Mol Cell; 73(3): 413-428.e7, 2019 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-30598363

9.

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

Annibaldi, Alessandro; Wicky John, Sidonie; Vanden Berghe, Tom; Swatek, Kirby N; Ruan, Jianbin; Liccardi, Gianmaria; Bianchi, Katiuscia; Elliott, Paul R; Choi, Sze Men; Van Coillie, Samya; Bertin, John; Wu, Hao; Komander, David; Vandenabeele, Peter; Silke, John; Meier, Pascal.

Mol Cell; 69(4): 566-580.e5, 2018 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-29452637

10.

Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.

Liu, Zikou; Dagley, Laura F; Shield-Artin, Kristy; Young, Samuel N; Bankovacki, Aleksandra; Wang, Xiangyi; Tang, Michelle; Howitt, Jason; Stafford, Che A; Nachbur, Ueli; Fitzgibbon, Cheree; Garnish, Sarah E; Webb, Andrew I; Komander, David; Murphy, James M; Hildebrand, Joanne M; Silke, John.

EMBO J; 40(23): e103718, 2021 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-34698396

11.

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.

Alvarez-Diaz, Silvia; Dillon, Christopher P; Lalaoui, Najoua; Tanzer, Maria C; Rodriguez, Diego A; Lin, Ann; Lebois, Marion; Hakem, Razq; Josefsson, Emma C; O'Reilly, Lorraine A; Silke, John; Alexander, Warren S; Green, Douglas R; Strasser, Andreas.

Immunity; 45(3): 513-526, 2016 09 20.

Artículo en Inglés | MEDLINE | ID: mdl-27523270

12.

Blocking cell death limits lung damage and inflammation from influenza.

Gupta, Nishma; Silke, John.

Nature; 628(8009): 726-727, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38600194

13.

Jekyll & Hyde: The Other Life of the Death Ligand TRAIL.

Lalaoui, Najoua; Silke, John.

Mol Cell; 65(4): 585-587, 2017 Feb 16.

Artículo en Inglés | MEDLINE | ID: mdl-28212746

14.

MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.

Jaco, Isabel; Annibaldi, Alessandro; Lalaoui, Najoua; Wilson, Rebecca; Tenev, Tencho; Laurien, Lucie; Kim, Chun; Jamal, Kunzah; Wicky John, Sidonie; Liccardi, Gianmaria; Chau, Diep; Murphy, James M; Brumatti, Gabriela; Feltham, Rebecca; Pasparakis, Manolis; Silke, John; Meier, Pascal.

Mol Cell; 66(5): 698-710.e5, 2017 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-28506461

15.

Unleashing TNF cytotoxicity to enhance cancer immunotherapy.

Freeman, Andrew J; Kearney, Conor J; Silke, John; Oliaro, Jane.

Trends Immunol; 42(12): 1128-1142, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34750058

16.

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.

Peltzer, Nieves; Darding, Maurice; Montinaro, Antonella; Draber, Peter; Draberova, Helena; Kupka, Sebastian; Rieser, Eva; Fisher, Amanda; Hutchinson, Ciaran; Taraborrelli, Lucia; Hartwig, Torsten; Lafont, Elodie; Haas, Tobias L; Shimizu, Yutaka; Böiers, Charlotta; Sarr, Aida; Rickard, James; Alvarez-Diaz, Silvia; Ashworth, Michael T; Beal, Allison; Enver, Tariq; Bertin, John; Kaiser, William; Strasser, Andreas; Silke, John; Bouillet, Philippe; Walczak, Henning.

Nature; 557(7703): 112-117, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29695863

17.

The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase.

Pierotti, Catia L; Jacobsen, Annette V; Grohmann, Christoph; Dempsey, Ruby K; Etemadi, Nima; Hildebrand, Joanne M; Fitzgibbon, Cheree; Young, Samuel N; Davies, Katherine A; Kersten, Wilhelmus J A; Silke, John; Lowes, Kym N; Jousset Sabroux, Hélène; Huang, David C S; van Delft, Mark F; Murphy, James M; Lessene, Guillaume.

Biochem J; 480(9): 665-684, 2023 05 15.

Artículo en Inglés | MEDLINE | ID: mdl-37115711

18.

HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis.

Freeman, Andrew J; Vervoort, Stephin J; Michie, Jessica; Ramsbottom, Kelly M; Silke, John; Kearney, Conor J; Oliaro, Jane.

EMBO Rep; 22(11): e53391, 2021 11 04.

Artículo en Inglés | MEDLINE | ID: mdl-34467615

19.

Necroptosis in chronic obstructive pulmonary disease, a smoking gun?

Pierotti, Catia L; Silke, John.

Immunol Cell Biol; 100(2): 79-82, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35023199

20.

Erratum: The diverse role of RIP kinases in necroptosis and inflammation.