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1.

Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.

Bharadwaj, Ravi; Lusi, Christina F; Mashayekh, Siavash; Nagar, Abhinit; Subbarao, Malireddi; Kane, Griffin I; Wodzanowski, Kimberly A; Brown, Ashley R; Okuda, Kendi; Monahan, Amanda; Paik, Donggi; Nandy, Anubhab; Anonick, Madison V; Goldman, William E; Kanneganti, Thirumala-Devi; Orzalli, Megan H; Grimes, Catherine Leimkuhler; Atukorale, Prabhani U; Silverman, Neal.

Immunity; 56(5): 998-1012.e8, 2023 05 09.

Artículo en Inglés | MEDLINE | ID: mdl-37116499

2.

Drosophilosophical: Re-thinking Adaptive Immunity in the Fly.

West, Cara; Silverman, Neal.

Cell; 169(2): 188-190, 2017 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-28388404

3.

Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila.

Liu, Bo; Zheng, Yonggang; Yin, Feng; Yu, Jianzhong; Silverman, Neal; Pan, Duojia.

Cell; 164(3): 406-19, 2016 Jan 28.

Artículo en Inglés | MEDLINE | ID: mdl-26824654

4.

Control of the innate immune response by the mevalonate pathway.

Akula, Murali K; Shi, Man; Jiang, Zhaozhao; Foster, Celia E; Miao, David; Li, Annie S; Zhang, Xiaoman; Gavin, Ruth M; Forde, Sorcha D; Germain, Gail; Carpenter, Susan; Rosadini, Charles V; Gritsman, Kira; Chae, Jae Jin; Hampton, Randolph; Silverman, Neal; Gravallese, Ellen M; Kagan, Jonathan C; Fitzgerald, Katherine A; Kastner, Daniel L; Golenbock, Douglas T; Bergo, Martin O; Wang, Donghai.

Nat Immunol; 17(8): 922-9, 2016 08.

Artículo en Inglés | MEDLINE | ID: mdl-27270400

5.

The Kinase IKKß Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila.

Goto, Akira; Okado, Kiyoshi; Martins, Nelson; Cai, Hua; Barbier, Vincent; Lamiable, Olivier; Troxler, Laurent; Santiago, Estelle; Kuhn, Lauriane; Paik, Donggi; Silverman, Neal; Holleufer, Andreas; Hartmann, Rune; Liu, Jiyong; Peng, Tao; Hoffmann, Jules A; Meignin, Carine; Daeffler, Laurent; Imler, Jean-Luc.

Immunity; 49(2): 225-234.e4, 2018 08 21.

Artículo en Inglés | MEDLINE | ID: mdl-30119996

6.

Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling.

Kleino, Anni; Ramia, Nancy F; Bozkurt, Gunes; Shen, Yanfang; Nailwal, Himani; Huang, Jing; Napetschnig, Johanna; Gangloff, Monique; Chan, Francis Ka-Ming; Wu, Hao; Li, Jixi; Silverman, Neal.

Immunity; 47(4): 635-647.e6, 2017 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-29045898

7.

ReaDAPting the Role of PGRP-SD in Bacterial Sensing and Immune Activation.

Monahan, Amanda; Kleino, Anni; Silverman, Neal.

Immunity; 45(5): 951-953, 2016 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-27851920

8.

The Kinase IKKß Regulates a STING-and NF-κB-Dependent Antiviral Response Pathway in Drosophila.

Goto, Akira; Okado, Kiyoshi; Martins, Nelson; Cai, Hua; Barbier, Vincent; Lamiable, Olivier; Troxler, Laurent; Santiago, Estelle; Kuhn, Lauriane; Paik, Donggi; Silverman, Neal; Holleufer, Andreas; Hartmann, Rune; Liu, Jiyong; Peng, Tao; Hoffmann, Jules A; Meignin, Carine; Daeffler, Laurent; Imler, Jean-Luc.

Immunity; 52(1): 200, 2020 01 14.

Artículo en Inglés | MEDLINE | ID: mdl-31940269

9.

cGAS-like receptors put a sting into the evolution of immune defence.

West, Cara; Silverman, Neal.

Nature; 597(7874): 34-35, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34373639

10.

p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila.

West, Cara; Silverman, Neal.

PLoS Pathog; 14(5): e1007020, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29746571

11.

Autophagic control of listeria through intracellular innate immune recognition in drosophila.

Yano, Tamaki; Mita, Shizuka; Ohmori, Hiroko; Oshima, Yoshiteru; Fujimoto, Yukari; Ueda, Ryu; Takada, Haruhiko; Goldman, William E; Fukase, Koichi; Silverman, Neal; Yoshimori, Tamotsu; Kurata, Shoichiro.

Nat Immunol; 9(8): 908-16, 2008 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-18604211

12.

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.

Boyer, Laurent; Magoc, Lorin; Dejardin, Stephanie; Cappillino, Michael; Paquette, Nicholas; Hinault, Charlotte; Charriere, Guillaume M; Ip, W K Eddie; Fracchia, Shannon; Hennessy, Elizabeth; Erturk-Hasdemir, Deniz; Reichhart, Jean-Marc; Silverman, Neal; Lacy-Hulbert, Adam; Stuart, Lynda M.

Immunity; 35(4): 536-49, 2011 Oct 28.

Artículo en Inglés | MEDLINE | ID: mdl-22018470

13.

SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans.

Paik, Donggi; Monahan, Amanda; Caffrey, Daniel R; Elling, Roland; Goldman, William E; Silverman, Neal.

J Immunol; 199(1): 263-270, 2017 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-28539433

14.

Dehydration triggers ecdysone-mediated recognition-protein priming and elevated anti-bacterial immune responses in Drosophila Malpighian tubule renal cells.

Zheng, Wenjing; Rus, Florentina; Hernandez, Ana; Kang, Ping; Goldman, William; Silverman, Neal; Tatar, Marc.

BMC Biol; 16(1): 60, 2018 05 31.

Artículo en Inglés | MEDLINE | ID: mdl-29855367

15.

Innate immune signaling in Drosophila is regulated by transforming growth factor ß (TGFß)-activated kinase (Tak1)-triggered ubiquitin editing.

Chen, Li; Paquette, Nicholas; Mamoor, Shahan; Rus, Florentina; Nandy, Anubhab; Leszyk, John; Shaffer, Scott A; Silverman, Neal.

J Biol Chem; 292(21): 8738-8749, 2017 05 26.

Artículo en Inglés | MEDLINE | ID: mdl-28377500

16.

Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation.

Okuda, Kendi; Tong, Mei; Dempsey, Brian; Moore, Kathryn J; Gazzinelli, Ricardo T; Silverman, Neal.

PLoS Pathog; 12(6): e1005669, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-27280707

17.

Editorial overview of Pearls Microbiome Series: E pluribus unum.

Hogan, Deborah A; Heitman, Joseph; Jabra-Rizk, Mary Ann; Knoll, Laura J; Leong, John M; Silverman, Neal.

PLoS Pathog; 17(8): e1009912, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-34464427

18.

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling.

Paquette, Nicholas; Broemer, Meike; Aggarwal, Kamna; Chen, Li; Husson, Marie; Ertürk-Hasdemir, Deniz; Reichhart, Jean-Marc; Meier, Pascal; Silverman, Neal.

Mol Cell; 37(2): 172-82, 2010 Jan 29.

Artículo en Inglés | MEDLINE | ID: mdl-20122400

19.

Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity.

Rus, Florentina; Flatt, Thomas; Tong, Mei; Aggarwal, Kamna; Okuda, Kendi; Kleino, Anni; Yates, Elisabeth; Tatar, Marc; Silverman, Neal.

EMBO J; 32(11): 1626-38, 2013 May 29.

Artículo en Inglés | MEDLINE | ID: mdl-23652443

20.

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

Weng, Dan; Marty-Roix, Robyn; Ganesan, Sandhya; Proulx, Megan K; Vladimer, Gregory I; Kaiser, William J; Mocarski, Edward S; Pouliot, Kimberly; Chan, Francis Ka-Ming; Kelliher, Michelle A; Harris, Phillip A; Bertin, John; Gough, Peter J; Shayakhmetov, Dmitry M; Goguen, Jon D; Fitzgerald, Katherine A; Silverman, Neal; Lien, Egil.

Proc Natl Acad Sci U S A; 111(20): 7391-6, 2014 May 20.

Artículo en Inglés | MEDLINE | ID: mdl-24799678

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Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.

Drosophilosophical: Re-thinking Adaptive Immunity in the Fly.

Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila.

Control of the innate immune response by the mevalonate pathway.

The Kinase IKKß Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila.

Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling.

ReaDAPting the Role of PGRP-SD in Bacterial Sensing and Immune Activation.

The Kinase IKKß Regulates a STING-and NF-κB-Dependent Antiviral Response Pathway in Drosophila.

cGAS-like receptors put a sting into the evolution of immune defence.

p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila.

Autophagic control of listeria through intracellular innate immune recognition in drosophila.

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.

SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans.

Dehydration triggers ecdysone-mediated recognition-protein priming and elevated anti-bacterial immune responses in Drosophila Malpighian tubule renal cells.

Innate immune signaling in Drosophila is regulated by transforming growth factor ß (TGFß)-activated kinase (Tak1)-triggered ubiquitin editing.

Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation.

Editorial overview of Pearls Microbiome Series: E pluribus unum.

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling.

Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity.

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.