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1.
Comput Inform Nurs ; 34(8): 369-75, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27270629

RESUMEN

Osteoporosis has recently been acknowledged as a major public health issue in developed countries because of the decrease in the quality of life of the affected person and the increase in public costs due to complete or partial physical disability. The aim of this study was to use the J48 algorithm as a classification task for data from women exhibiting changes in bone densitometry. The study population included all patients treated at the diagnostic center for bone densitometry since 2010. Census sample data collection was conducted as all elements of the population were included in the sample. The service in question provides care to patients via the Brazilian Unified Health System and private plans. The results of the classification task were analyzed using the J48 algorithm, and among the dichotomized variables associated with a diagnosis of osteoporosis, the mean accuracy was 74.0 (95% confidence interval [CI], 61.0-68.0) and the mean area under the curve of the receiver operating characteristic (ROC) curve was 0.65 (95% CI, 0.64-0.66), with a mean sensitivity of 76.0 (95% CI, 76.0-76.0) and a mean specificity of 48.0 (95% CI, 46.0-49.0). The analyzed results showed higher values of sensitivity, accuracy, and curve of the ROC area in experiments conducted with individuals with osteoporosis. Most of the generated rules were consistent with the literature, and the few differences might serve as hypotheses for further studies.


Asunto(s)
Minería de Datos , Osteoporosis/diagnóstico , Medición de Riesgo/métodos , Anciano , Algoritmos , Brasil , Estudios Transversales , Femenino , Humanos , Persona de Mediana Edad , Osteoporosis/diagnóstico por imagen , Calidad de Vida , Factores de Riesgo , Sensibilidad y Especificidad
2.
Int J Gynecol Cancer ; 23(3): 437-41, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23354370

RESUMEN

OBJECTIVE: We performed a systematic review and a meta-analysis to estimate the prevalence of human papillomavirus (HPV) in ovarian cancer. METHODS: A comprehensive search of the Cochrane Library, MEDLINE, CANCERLIT, LILACS, Grey literature and EMBASE was performed for articles published from January 1990 to March 2012. The following MeSH (Medical Subject Headings) terms were searched: "ovarian tumor" or "ovarian cancers" and "HPV" or "human papillomavirus." Included were case-control and cross-sectional studies, prospective or retrospective, that evaluated clinical ovarian cancer and provided a clear description of the use of in situ hybridization, Southern blot hybridization, and polymerase chain reaction. The statistical analysis was performed using REVMAN 5.0. RESULTS: In total, 24 primary studies were included in this meta-analysis. Studies from 11 countries on 3 continents contained data on HPV and ovarian cancer, including 889 subjects. Overall, the HPV prevalence in patients with ovarian cancer was 17.5 (95% confidence interval [CI], 15.0%-20.0%). Human papillomavirus prevalence ranged from 4.0% (95% CI, 1.7%-6.3%) in Europe to 31.4% (95% CI, 26.9%-35.9%) in Asia. An aggregate of 4 case-control studies from Asia showed an odds ratio of 2.48 (95% CI, 0.64-9.57). CONCLUSIONS: We found a high prevalence of HPV-positive DNA in ovarian cancer cases, but the role of HPV in ovarian cancer remains inconclusive. Further studies are needed to control case to answer this question.


Asunto(s)
Neoplasias Ováricas/virología , Infecciones por Papillomavirus/epidemiología , Infecciones Tumorales por Virus/epidemiología , Brasil/epidemiología , Femenino , Humanos , Neoplasias Ováricas/complicaciones , Papillomaviridae , Prevalencia
3.
Arch Dermatol Res ; 315(6): 1571-1576, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-36723680

RESUMEN

To compare the quality of life (QoL) of children with and without atopic dermatitis (AD) and that of their caregivers and to assess their QoL according to different degrees of AD. This is a cross-sectional, case-control study conducted with patients aged between 4 and 12 years with and without AD and their caregivers. Patients were treated at the Pediatric Dermatology Outpatient Center and the Childcare Center of the Joana de Gusmão Children's Hospital, respectively, from June 2021 to March 2022. The QoL Assessment Scale Autoquestionnaire Qualité de Vie Infant Imagé (AUQEI) was applied to children and adolescents with AD and the control group while the World Health Organization Quality of Life assessment instrument was administered to their caregivers. Fifty cases and fifty controls were included in this study. When assessing the QoL of the case and control groups, statistically significant differences were found in the domains of the AUQUEI instrument. Regarding QoL and AD severity, a statistically significant difference was seen (p = 0.027) when comparing moderate and severe SCORAD scores. When comparing the QoL of children with and without AD, a difference was seen between the two groups. The QoL of AD patients was worse and related to the severity of the disease. A better QoL was found among the caregivers in the control group. In the case group, the higher the SCORAD score, the worse the QoL. No relationship was found between AD severity and the QoL of the caregivers in the case group.


Asunto(s)
Dermatitis Atópica , Calidad de Vida , Lactante , Adolescente , Niño , Humanos , Preescolar , Estudios Transversales , Cuidadores , Estudios de Casos y Controles , Índice de Severidad de la Enfermedad , Encuestas y Cuestionarios
4.
Int J Gynecol Cancer ; 22(3): 343-7, 2012 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-22214962

RESUMEN

OBJECTIVE: We performed a systematic review and meta-analyses to estimate the prevalence of human papillomavirus (HPV) in breast carcinoma and to explore the reasons for the ongoing controversies about this issue. MATERIALS AND METHODS: A comprehensive search of the Cochrane Library, MEDLINE, CANCERLIT, LILACS, and EMBASE databases was performed for papers published from January 1990 to January 2011. The medical subject heading terms were searched for the following: breast neoplasm, breast lesions, breast cancer, and HPV or human papillomavirus. Statistical analysis was performed using REVMAN 5.0. RESULTS: Twenty-nine primary studies, including 2211 samples, were analyzed. Overall, HPV prevalence in patients with breast cancer was 23.0% (95% CI, 21.2%-24.8%). The prevalence of HPV ranged from 13.4% (95% CI, 10.2%-16%) in Europe to 42.9% (95% CI, 36.4%-49.4%) in North America and Australia. The prevalence of HPV in controls was 12.9%. Combinations of 9 case-control studies showed that breast cancer was associated with HPV (odds ratio, 5.9; 95% CI, 3.26-10.67). CONCLUSION: We found a high prevalence of HPV DNA in breast cancer. There is strong evidence to suggest that HPV has an important role in the development of breast cancer.


Asunto(s)
Neoplasias de la Mama/epidemiología , Carcinoma/epidemiología , Infecciones por Papillomavirus/epidemiología , Algoritmos , Alphapapillomavirus/fisiología , Neoplasias de la Mama/complicaciones , Neoplasias de la Mama/terapia , Neoplasias de la Mama/virología , Vacunas contra el Cáncer/uso terapéutico , Carcinoma/complicaciones , Carcinoma/terapia , Femenino , Humanos , Metaanálisis como Asunto , Infecciones por Papillomavirus/complicaciones , Infecciones por Papillomavirus/terapia , Vacunas contra Papillomavirus/uso terapéutico , Prevalencia
5.
Stud Health Technol Inform ; 285: 239-244, 2021 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-34734880

RESUMEN

Mobile Health has been increasingly present in healthcare due to the wide availability of applications for smartphones, however, robust assessment methods must be considered, seeking to provide evidence for clinical practice and mHealth solutions. This research presents the assessment of applications aimed at detecting and preventing falls for the elderly, available for Android and IOS, through the Mobile App Rating Scale. Based on the results presented, it can be concluded that the fall detection and prevention applications for the elderly available for Android and IOS showed good quality after rigorous evaluation.


Asunto(s)
Accidentes por Caídas , Aplicaciones Móviles , Telemedicina , Accidentes por Caídas/prevención & control , Anciano , Atención a la Salud , Humanos , Teléfono Inteligente
6.
Schizophr Bull ; 46(6): 1482-1497, 2020 12 01.
Artículo en Inglés | MEDLINE | ID: mdl-32506125

RESUMEN

Prepulse inhibition (PPI) of startle is an operational measure of sensorimotor gating that is often impaired in patients with schizophrenia. Despite the large number of studies, there is considerable variation in PPI outcomes reported. We conducted a systematic review and meta-analysis investigating PPI impairment in patients with schizophrenia compared with healthy control subjects, and examined possible explanations for the variation in results between studies. Major databases were screened for observational studies comparing healthy subjects and patients with schizophrenia for the prepulse and pulse intervals of 60 and 120 ms as primary outcomes, ie, PPI-60 and PPI-120. Standardized mean difference (SMD) and 95% confidence intervals (CI) were extracted and pooled using random effects models. We then estimated the mean effect size of these measures with random effects meta-analyses and evaluated potential PPI heterogeneity moderators, using sensitivity analysis and meta-regressions. Sixty-seven primary studies were identified, with 3685 healthy and 4290 patients with schizophrenia. The schizophrenia group showed reduction in sensorimotor gating for both PPI-60 (SMD = -0.50, 95% CI = [-0.61, -0.39]) and PPI-120 (SMD = -0.44, 95% CI = [-0.54, -0.33]). The sensitivity and meta-regression analysis showed that sample size, gender proportion, imbalance for gender, source of control group, and study continent were sources of heterogeneity (P < .05) for both PPI-60 and PPI-120 outcomes. Our findings confirm a global sensorimotor gating deficit in schizophrenia patients, with overall moderate effect size for PPI-60 and PPI-120. Methodological consistency should decrease the high level of heterogeneity of PPI results between studies.


Asunto(s)
Inhibición Prepulso/fisiología , Esquizofrenia/fisiopatología , Filtrado Sensorial/fisiología , Humanos
7.
Stud Health Technol Inform ; 264: 878-882, 2019 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-31438050

RESUMEN

Diabetic Retinopathy (DR) is one of the most common microvascular complications presenting by patients diagnosticated with diabetic diseases. Uncontrolled hyperglycemia may manifest as visual impairment and blindness. The early detection of DR is essential to minimize the risk and consequence of visual diminishing. The standard gold diagnoses tool relies on different imaging modalities and requires a judgment of expert photographers, which are not available in most of the primary care centers or remote location. In that scenario, an automate or semiautomated DR screening systems can contribute to improving the accuracy of the diagnostic. Thus, we performed a Systematic Review and Meta-Analysis to evaluate the Decision Support Systems (DSS) in diagnosing DR. The overall Diagnostic Odds Ratio was 73.15 (95%CI: 37.54-142.50), sensitivity was 97.70 (95%CI: 97.50-97.90) and specificity was 90.30 (95%CI: 90.00-90.60). Our results corroborate with the concept of usefulness of DSSs in early diagnosis, screening and preliminary evaluation of suspicious images of DR.


Asunto(s)
Retinopatía Diabética , Toma de Decisiones , Sistemas Especialistas , Humanos , Tamizaje Masivo , Programas Informáticos
8.
Ann Anat ; 216: 75-81, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29229272

RESUMEN

The calcaneal tendon extracellular matrix (ECM) is composed of collagen, non-collagenous glycoproteins and proteoglycans, and able to adapt to various biomechanical stimuli. The objective of this study was to analyze the response of different resistance-training protocols, such as hypertrophy, strength and resistance, on the organization of the calcaneal tendon after training. Wistar rats were divided into four groups: untrained (UT), resistance training (RT), hypertrophy training (HT), and strength training (ST). The protocol in a vertical climbing platform was performed thrice per week over twelve weeks. For biochemical study, the tendons of each group were minced and analyzed for gelatinases, quantification of non-collagenous proteins, sulfated glycosaminoglycans, and hydroxyproline. For morphological analysis, sections were stained with HE and toluidine blue. Non-stained sections were used for birefringence analysis under polarization microscopy. The highest hydroxyproline concentrations were found in HT (154.8±14.2) and RT (173.6±25.2) compared with UT (122.4±27.0). A higher concentration of non-collagenous proteins was detected in the RT group (14.98mg/g) compared with the other groups. In polarization microscopy, major birefringence was observed in HT and the lowest in ST compared with UT, indicating higher organization of collagen bundles in HT. In analysis for zymography, the presence of latent MMP-9 was more prominent in the ST group and the active MMP-9 more prominent in the HT group. For MMP-2, significant differences in the latent isoform between the HT (184,867±6765) and UT (173,018±9696) groups were found. In sections stained with toluidine blue (TB), higher metachromasia was observed in the tendon's distal region in HT and RT groups, indicating a greater amount of proteoglycans. We conclude that the different training protocols produced different responses in the ECM. The remarkable presence of MMP-2 and -9 in the hypertrophy training group may be related to the highest organization of collagen bundles and possibly a more efficient remodeling process, observed in that group, as demonstrated by images and measurements of birefringence.


Asunto(s)
Tendón Calcáneo/metabolismo , Tendón Calcáneo/fisiología , Matriz Extracelular/metabolismo , Matriz Extracelular/fisiología , Condicionamiento Físico Animal/fisiología , Entrenamiento de Fuerza , Animales , Colágeno/metabolismo , Gelatinasas/metabolismo , Glicosaminoglicanos/metabolismo , Hidroxiprolina/metabolismo , Masculino , Metaloproteinasa 2 de la Matriz/biosíntesis , Metaloproteinasa 9 de la Matriz/biosíntesis , Proteínas Musculares/metabolismo , Fuerza Muscular , Músculo Esquelético/anatomía & histología , Músculo Esquelético/fisiología , Ratas , Ratas Wistar
9.
Cells ; 7(9)2018 Aug 31.
Artículo en Inglés | MEDLINE | ID: mdl-30200326

RESUMEN

Tendon injuries represent a clinical challenge in regenerative medicine because their natural repair process is complex and inefficient. The high incidence of tendon injuries is frequently associated with sports practice, aging, tendinopathies, hypertension, diabetes mellitus, and the use of corticosteroids. The growing interest of scientists in using adipose-derived mesenchymal stem cells (ADMSC) in repair processes seems to be mostly due to their paracrine and immunomodulatory effects in stimulating specific cellular events. ADMSC activity can be influenced by GDF-5, which has been successfully used to drive tenogenic differentiation of ADMSC in vitro. Thus, we hypothesized that the application of ADMSC in isolation or in association with GDF-5 could improve Achilles tendon repair through the regulation of important remodeling genes expression. Lewis rats had tendons distributed in four groups: Transected (T), transected and treated with ADMSC (ASC) or GDF-5 (GDF5), or with both (ASC+GDF5). In the characterization of cells before application, ADMSC expressed the positive surface markers, CD90 (90%) and CD105 (95%), and the negative marker, CD45 (7%). ADMSC were also differentiated in chondrocytes, osteoblast, and adipocytes. On the 14th day after the tendon injury, GFP-ADMSC were observed in the transected region of tendons in the ASC and ASC+GDF5 groups, and exhibited and/or stimulated a similar genes expression profile when compared to the in vitro assay. ADMSC up-regulated Lox, Dcn, and Tgfb1 genes expression in comparison to T and ASC+GDF5 groups, which contributed to a lower proteoglycans arrangement, and to a higher collagen fiber organization and tendon biomechanics in the ASC group. The application of ADMSC in association with GDF-5 down-regulated Dcn, Gdf5, Lox, Tgfb1, Mmp2, and Timp2 genes expression, which contributed to a lower hydroxyproline concentration, lower collagen fiber organization, and to an improvement of the rats' gait 24 h after the injury. In conclusion, although the literature describes the benefic effect of GDF-5 for the tendon healing process, our results show that its application, isolated or associated with ADMSC, cannot improve the repair process of partial transected tendons, indicating the higher effectiveness of the application of ADMSC in injured Achilles tendons. Our results show that the application of ADMSC in injured Achilles tendons was more effective in relation to its association with GDF-5.

10.
Stud Health Technol Inform ; 245: 1380, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-29295459

RESUMEN

The aim of this study was to evaluate the accuracy of decision support systems in the diagnosis of breast cancer by means of a systematic review and meta-analysis of studies of diagnostic accuracy. The first step of the research, which consisted of the initial research of abstracts and titles identified from the research strategy in the databases was performed by two researchers independently. In this stage, 622 references were retrieved in the databases and, through a consensus meeting, 183 articles were selected for full reading.


Asunto(s)
Neoplasias de la Mama/terapia , Sistemas de Apoyo a Decisiones Clínicas , Femenino , Humanos
11.
Stud Health Technol Inform ; 245: 1287, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-29295372

RESUMEN

The aim of this study was to use the Data Mining to analyze the profile of the use of contraceptive methods in a university population. We used a database about sexuality performed on a university population in southern Brazil. The results obtained by the generated rules are largely in line with the literature and epidemiology worldwide, showing significant points of vulnerability in the university population. Validation measures of the study, as such, accuracy, sensitivity, specificity, and area under the ROC curve were higher or at least similar as compared to recent studies using the same methodology.


Asunto(s)
Conducta Anticonceptiva , Minería de Datos , Conducta Sexual , Adolescente , Brasil , Anticoncepción , Femenino , Humanos , Masculino , Estudiantes , Universidades , Adulto Joven
12.
Rev Soc Bras Med Trop ; 48(6): 665-73, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26676490

RESUMEN

INTRODUCTION: Hepatitis C is a public health problem of global dimensions, affecting approximately 200 million people worldwide. The main objective of this study was to estimate the incidence rate of hepatitis C in Brazil during the period between 2001 and 2012. METHODS: An epidemiological, temporal, and descriptive study was performed using data from the Information System for Reportable Diseases. RESULTS: Between 2001 and 2012, a total of 151,056 hepatitis C cases were recorded, accounting for 30.3% of all hepatitis notifications in Brazil. The average gross coefficient for the analysis period was 6.7 new cases per 100,000 inhabitants. The regions with the highest rates were the Southeast region (8.7 new cases/100,000 inhabitants) and the South (13.9 new cases/100,000 inhabitants). There was a predominance of men with respect to the incidence rate (8.0 new cases/100,000 inhabitants) compared to women (5.5 new cases/100,000 inhabitants). Injection drug use was the most common source of infection, and members of the white race, residents of urban areas, and those aged 60 to 64 years had the highest incidences. CONCLUSIONS: Over the last 10 years, the incidence of hepatitis C in Brazil has increased, mainly in the South and Southeast. The adoption of fast, accurate diagnostic methods, together with epidemiological awareness, can facilitate early intervention measures for adequate control of the disease.


Asunto(s)
Hepatitis C/epidemiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Brasil/epidemiología , Niño , Preescolar , Notificación de Enfermedades , Femenino , Humanos , Incidencia , Lactante , Masculino , Persona de Mediana Edad , Factores Socioeconómicos , Adulto Joven
13.
Cad Saude Publica ; 31(1): 26-38, 2015 Jan.
Artículo en Portugués | MEDLINE | ID: mdl-25715289

RESUMEN

The aim of this study was to determine the accuracy of Bayesian networks in supporting breast cancer diagnoses. Systematic review and meta-analysis were carried out, including articles and papers published between January 1990 and March 2013. We included prospective and retrospective cross-sectional studies of the accuracy of diagnoses of breast lesions (target conditions) made using Bayesian networks (index test). Four primary studies that included 1,223 breast lesions were analyzed, 89.52% (444/496) of the breast cancer cases and 6.33% (46/727) of the benign lesions were positive based on the Bayesian network analysis. The area under the curve (AUC) for the summary receiver operating characteristic curve (SROC) was 0.97, with a Q* value of 0.92. Using Bayesian networks to diagnose malignant lesions increased the pretest probability of a true positive from 40.03% to 90.05% and decreased the probability of a false negative to 6.44%. Therefore, our results demonstrated that Bayesian networks provide an accurate and non-invasive method to support breast cancer diagnosis.


Asunto(s)
Teorema de Bayes , Neoplasias de la Mama/diagnóstico , Diagnóstico por Computador , Femenino , Humanos , Mamografía , Informática Médica , Sensibilidad y Especificidad
14.
Artículo en Portugués | LILACS, BBO | ID: biblio-1009625

RESUMEN

Introdução: Mais de 550 mil casos de tumor de cabeça e pescoço surgem anualmente, e estes constituem a 5ª neoplasia mais prevalente no mundo. As neoplasias de cabeça e pescoço tem etiologia multifatorial, onde se destacam como principais agentes pre-oncologicos, segundo a literatura, o tabaco, álcool, HPV, exposição ao sol e o próprio envelhecimento. As lesões neoplásicas geralmente são detectadas tardiamente por serem assintomáticas, e em decorrência disso os tumores são descobertos em uma fase muito avançada, deixando graves sequelas e um baixo índice de sobrevida. Métodos: Aplicaram-se questionários em 35 pacientes com diagnostico de tumor de cabeça e pescoço, e em 35 pacientes sem neoplasias diagnosticadas. O questionário avaliou os fatores pre-oncogenicos de cada grupo. Resultados: Observou-se dentre os pacientes com neoplasia: 71,4% sendo do sexo masculino; 94,3% caucasianos; 77,1% tendo histórico de câncer na família; 73,5% já fizeram uso de tabaco; 37,1% foram etilistas e 86,7% tiveram um alto índice de radiação solar. Já no grupo de pacientes sem neoplasias, foi observado: 45,7% sendo do sexo masculino; 82,9% caucasianos; 65,7% tendo histórico de câncer na família; 39,3% fizeram uso de tabaco; 8,6% foram etilistas e 44,1% tiveram um alto índice de radiação solar. Conclusão: Mediante o que foi pesquisado, pode-se afirmar que a maioria dos pacientes com neoplasias possuíam fatores pre-oncogenicos elevados. Já no grupo sem neoplasias diagnosticadas, encontrou-se um índice menor durante a pesquisa.


Introduction: More than 550.000 cases of head and neck tumors are discovered annually, being the 5th most prevalent neoplasm in the world. The number of tumor cases has been steadily increasing over the last few years around the world. The head and neck neoplasms have a multifactorial etiology, in which tobacco, alcohol, HPV, exposure to the sun and aging standout as the main pre-oncological agents. Neoplastic lesions are usually discovered too late, since they are asymptomatic, and as a result tumors are discovered at a very advanced stage, leaving severe sequelae and a low survival rate. Methods: Questionnaires were applied to 35 patients with diagnosis of head and neck tumors and to 35 patients without diagnosed neoplasms. This questionnaire evaluated the pre-oncogenic factors of each group. Results: It was observed among the patients with neoplasia: 71.4% were male; 94.3% Caucasians; 77.1% reported having a family history of cancer; 73.5% of patients have used tobacco; 37.1% reported having already been alcoholic drinker sand 86.7% had a high index of solar radiation. In the group of patients without neoplasias, 45.7% were male; 82.9% Caucasians; 65.7% reported having a family history of cancer; 39.3% of the patients have already used tobacco; 8.6% reported having already been alcoholic drinker sand 44.1% had a high index of solar radiation. Conclusion: Based on this search, it can be stated that the majority of patients with neoplasias had high pre-oncogenic factors. In the group without diagnosed neoplasms, a lower index was found during the study.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Neoplasias de Cabeza y Cuello , Oncología Médica , Factores de Riesgo
15.
Rev Soc Bras Med Trop ; 47(4): 483-9, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-25229290

RESUMEN

INTRODUCTION: The aim of this study was to estimate the incidence of tuberculous meningitis in the State of Santa Catarina (SC), Brazil, during the period from 2001 to 2010. METHODS: Ecological, temporal, and descriptive methods were employed using data obtained from the Information System on Disease Notification (Sistema de Informação de Agravos de Notificação). RESULTS: One hundred sixteen reported cases of tuberculous meningitis occurred from 2001 to 2010, corresponding to 1.2% (0.2 cases/100,000 inhabitants) of all meningitis cases reported in SC. There was a predominance of new cases in males, corresponding to 56.9% of new cases (0.2 cases/100,000 inhabitants; males vs. females; p=0.374), in patients aged 20-39 years, corresponding to 52.6% of new cases (0.5 cases/100,000 inhabitants; 20-39 years versus others; p<0.001), and in urban areas, corresponding to 91.4% of new cases (0.2 cases/100,000 inhabitants; urban vs. rural; p=0.003). In 48.3% of cases, the outcome was death. CONCLUSIONS: The incidence rate of tuberculous meningitis in SC has increased within the last decade, with the most affected population comprising young adult white males with an average education. Thus, tuberculous meningitis remains a serious disease, emphasizing the need for disease prevention with vaccination campaigns against tuberculosis, the development of faster and more accurate diagnostic methods, and the use of current epidemiological knowledge regarding the disease to facilitate the establishment of early treatment.


Asunto(s)
Notificación de Enfermedades , Tuberculosis Meníngea/epidemiología , Adolescente , Adulto , Brasil/epidemiología , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Población Rural , Población Urbana , Adulto Joven
16.
Rev Soc Bras Med Trop ; 47(2): 170-8, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24861290

RESUMEN

INTRODUCTION: The aim of this study was to establish the incidence rates of congenital syphilis in the South Region of Brazil from 2001 to 2009. METHODS: Temporal ecological and descriptive study based on the cases recorded by the System of Information of Notifiable Diseases. RESULTS: The incidence of congenital syphilis has been increasing in the South Region of Brazil since 2004; the highest incidence rates were in women who received prenatal care (113.5 new cases per 100,000 births, p<0.001), who were diagnosed with syphilis at pregnancy (69.8 new cases per 100,000 births, p=0.001), and whose partner did not undergo treatment for syphilis (53.1 new cases per 100,000 births, p=0.001). CONCLUSIONS: The population of the present study mostly consisted of adult black women with low educational levels who attended prenatal care, who were diagnosed with syphilis during pregnancy, and whose partners were not treated for syphilis. Based on these results, actions are recommended to reduce the incidence of this disease, which is preventable by early diagnosis and appropriate treatment. The present was merely an ecological study; therefore, further investigations are necessary to elucidate the causes of these findings.


Asunto(s)
Transmisión Vertical de Enfermedad Infecciosa/estadística & datos numéricos , Complicaciones Infecciosas del Embarazo/epidemiología , Sífilis Congénita/epidemiología , Adolescente , Adulto , Brasil/epidemiología , Notificación de Enfermedades , Escolaridad , Femenino , Humanos , Incidencia , Embarazo , Adulto Joven
17.
Rev. odontol. Univ. Cid. São Paulo (Online) ; 30(2): 144-156, abr.-jun. 2018. Tabelas
Artículo en Portugués | LILACS, BBO | ID: biblio-966094

RESUMEN

Introdução: Devido ao comprometimento físico ou mental, os pacientes com necessidades especiais apresentam dificuldades em realizar sua higiene bucal e assim muitos deles acabam recebendo auxílio de outra pessoa, seja um familiar ou cuidador. Objetivo: Buscou-se avaliar o conhecimento de pais ou responsáveis, sobre a saúde bucal dos seus filhos com necessidades especiais, em uma Clínica Odontológica Universitária Catarinense. Métodos: Foi realizado um estudo transversal, descritivo, com abordagem quantitativa. A população foi composta por pais ou responsáveis pelos pacientes que frequentaram uma Clínica Odontológica Universitária no município de Criciúma/SC, de agosto a setembro de 2016. Dos questionários aplicados, foram excluídos os que não estavam respondidos corretamente, resultando no total de 32 questionários. Resultados: Quanto à participação da higiene bucal dos pacientes, 51,6% auxiliam seus filhos. Observou-se que a prática da escovação dental ocorre de duas a três vezes ao dia em grande parte dos pacientes (71,9%; n=23), com relevância estatística (p<0,007). O esclarecimento sobre saúde bucal aos filhos é dado pelos pais ou responsáveis (78,1%), sendo mais frequentemente instruídos pela mãe (75,0%; n=18). Metade dos pais/responsáveis classificou a saúde bucal do seu filho como uma condição oral boa (50,0%). Entre os aspectos facilitadores relatados pelos responsáveis para manter a saúde bucal do PNE, 38,7% sugeriram a instalação de centros de referência habilitados e maior número de profissionais, além do trabalho multidisciplinar (19,4%). Conclusão: Os pais/responsáveis dos pacientes com necessidades especiais apresentaram conhecimento satisfatório sobre a saúde bucal de seus filhos.


Introduction: Due to the physical or mental impairment, patients with special needs have restrictions when performing their oral hygiene, so many of them end up getting help from another person, whether a relative or caregiver. Objective: We sought to evaluate the knowledge of parents or guardians on the oral health of their children with special needs in a University Dental Clinic in Santa Catarina. Methods: A transverse study, descriptive with quantitative approach was held. The population was composed by parents or responsibles by patients that attended the Dental Clinic at the University in the town of Criciúma/SC between August 2016 till September 2016. From the questionnaires applied were excluded the ones that were not answered correctly, resulting in the total of 32 questionnaires. Results: Regarding the oral hygiene of the patients, 51,6% help their children. Was observed that the practice of the dental brushing occurs twice to three times a day, a big part of the patients (71,9%; n = 23), with relevant statistics (p <0,007) the clarification about oral health to the children is given by parents or responsible (78,1%), being more frequently instructed by the mother (75,0%; n = 18). Half of the parents/ responsible rated the oral health condition of their children as good (50,0%). Between the aspects reported by the responsible for keeping the oral health of the patients with special needs, 38,7% claim on installing qualified referral centers and more professionals; beyond to the multidisciplinary work (19.4%). Conclusions: Parents and/or guardians of patients with special needs have satisfactory knowledge about the oral health of their children.


Asunto(s)
Salud Bucal , Personas con Discapacidad , Conocimiento
18.
Rev. odontol. Univ. Cid. São Paulo (Online) ; 30(2): 116-131, abr.-jun. 2018. Tabelas
Artículo en Portugués | LILACS, BBO | ID: biblio-965994

RESUMEN

O edentulismo ainda e considerado um grande problema para a saúde publica, no Brasil. Acomete parte da população, em regiões distintas e diferentes faixas etárias. Alguns municípios brasileiros aderiram aos Laboratórios Regionais de Próteses Dentarias para minimizar essa condição; assim, buscou-se avaliar o desempenho e a satisfação dos usuários de próteses totais mucossuportadas fornecidas pelo Sistema Único de Saúde. Estudo transversal, de analise descritiva e abordagem quali-quantitativa, com amostra censitária de 115 usuários que receberam próteses totais superiores e/ou inferiores no período de julho de 2013 até julho de 2014. Foram aplicados os questionários OHIP-14 e a Escala Visual Analógica para avaliar a satisfação e desempenho. A idade mediana foi 59,0 (53,0-68,0) anos. Renda mensal prevalente foi de até um salário mínimo (60,0%; n=69). O grau de alfabetização mais comum foi ensino fundamental incompleto (68,7%; n=79). O desempenho mediano associado aos diferentes tipos de próteses foi de 99,0 para a superior, 95,0 para a inferior e 97,0 para ambas as próteses, resultados considerados estatisticamente significativos (p=0,047). Usuários do SUS que receberam próteses totais mucossuportadas estão satisfeitos com a reabilitação. Quanto ao desempenho das próteses avaliadas, constatou-se diferença estatisticamente significativa para reabilitação com prótese superior, inferior ou para ambas.


Edentulism is still considered a great problem for public health in Brazil. Affect the population in different regions and different ages. Some cities have joined the Regional Laboratories of Dental Prosthetics to minimize this condition, so it has been intended to evaluate the performance and user satisfaction of complete denture prosthesis provided by the Unified Health System. Cross-sectional study of descriptive analysis and qualitative and quantitative approach, with census sample of 115 users who have received upper and/ or lower complete dentures from July 2013 to July 2014. We applied the OHIP-14 questionnaire and Visual Analog Scale to assess satisfaction and performance. The median age was 59.0 (53.0 to 68.0) years. Prevalent monthly income was up to one minimum wage (60.0%; n = 69). The most common grade literacy was incomplete primary education (68.7%; n = 79). Average performance associated with different types of prosthesis was 99.0 for higher, 95.0 was lower and 97.0 for both prostheses, results were considered statistically significant (p = 0.047). SUS users who have received complete dentures prosthesis are satisfied with the rehabilitation. As for the performance of prosthesis assessed, there was no statistically significant difference for rehabilitation with upper dentures, lower or both.


Asunto(s)
Salud Bucal , Salud Pública , Dentadura Completa , Odontología Comunitaria
19.
Stud Health Technol Inform ; 192: 1135, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23920909

RESUMEN

Using the framework for developing parallel applications Java Parallel Programming Framework were conducted performance analysis of an application for the clustering data by the method of fuzzy logic combined with Gustafson-Kessel algorithm. In addition to running in a distributed environment, for comparative purposes, were also conducted collections of processing time in environments with a single Personal Computer approach. With the results obtained by collecting time of application, there was a statistical analysis to validate the application and the algorithm as well as the use of computational clustering as a way to increase performance applications.


Asunto(s)
Redes de Comunicación de Computadores , Minería de Datos , Lenguajes de Programación , Conducta Sexual/estadística & datos numéricos , Programas Informáticos , Estudiantes/estadística & datos numéricos , Universidades/estadística & datos numéricos , Algoritmos , Análisis por Conglomerados , Lógica Difusa , Humanos , Reconocimiento de Normas Patrones Automatizadas/métodos , Dinámica Poblacional
20.
Rev. odontol. Univ. Cid. São Paulo (Online) ; 29(2): 118-128, maio-ago 2017.
Artículo en Portugués | LILACS, BBO | ID: biblio-875168

RESUMEN

Pessoas com deficiência são indivíduos que apresentam algum desvio de normalidade, podendo ser de ordem física, mental, sensorial, comportamental e/ou de crescimento, e que necessitam de cuidados diferenciados por um determinado período de tempo ou por toda a vida. Estudos que analisam o perfil epidemiológico de saúde bucal dos pacientes com necessidades especiais indicam alta prevalência de alterações como: cárie, edentulismo, traumatismo e de doença periodontal decorrente de uma higiene bucal precária. O objetivo deste estudo foi identificar a prevalência de alterações bucais em pacientes com necessidades especiais, atendidos na clínica de odontologia da Universidade do Extremo Sul Catarinense. Foi caracterizado como um estudo transversal, descritivo e quali-quantitativo, totalizando uma amostra de 73 prontuários de pacientes com idade entre 1 e 70 anos, predominantemente portadores de transtorno do espectro autista (23,3%). A pesquisa con-statou que 68,1% dos pesquisados apresentaram acometimento de cárie, 55,6% de ausências dentárias e 50% de tártaro. Concluiu-se que alterações bucais podem ser prevenidas ou minimizadas, através do trabalho da equipe multidisciplinar no manejo do paciente portador de necessidade especial e programa de prevenção em saúde bucal


Persons with disability are individuals who have some normality deviation that can be physical, mental, sen¬sory, behavioral and/or growth, which need special care for a certain period of time or for life. Studies that analyze the epidemiology of oral health of patients with special needs indicate high prevalence of alterations such as caries, tooth loss, trauma and periodontal disease resulting from a poor oral hygiene. The aim of this study was to identify the prevalence of oral abnormalities in patients with special needs attended at the dental clinic of UNESC. It was characterized as a cross-sectional, descriptive, qualitative and quantitative study, with a total sample of 73 records, ages from 1 to 70 years old, predominantly carriers of the autism spectrum (23.3%). The survey found that 68.1% of respondents had caries involvement, 55.6% dental absences and 50% tartar. It was concluded that oral diseases can be prevented or minimized through the work of the multidisciplinary team in the management of patients with special need, and prevention program in oral health


Asunto(s)
Humanos , Masculino , Femenino , Lactante , Anciano , Personas con Discapacidad , Salud Bucal , Patología , Pacientes
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