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1.
The vasopressin V1b receptor as a therapeutic target in stress-related disorders.
Curr Drug Targets CNS Neurol Disord;
2(3): 191-200, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12769799
2.
SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist. II: Behavioral profile predictive of an atypical antipsychotic activity.
Neuropsychopharmacology;
28(11): 1889-902, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12902993
3.
Functional and pharmacological characterization of the first specific agonist and antagonist for the V1b receptor in mammals.
Stress;
6(3): 199-206, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-13129813
4.
Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.
Proc Natl Acad Sci U S A;
99(9): 6370-5, 2002 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-11959912
5.
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor(1) receptor antagonist. II. Characterization in rodent models of stress-related disorders.
J Pharmacol Exp Ther;
301(1): 333-45, 2002 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-11907191
6.
SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.
CNS Drug Rev;
9(1): 3-20, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12595909
7.
Characterization of (2S,4R)-1-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a selective and orally active vasopressin V1b receptor antagonist.
J Pharmacol Exp Ther;
300(3): 1122-30, 2002 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-11861823
8.
SSR240600 [(R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin 1 receptor: II. Neurochemical and behavioral characterization.
J Pharmacol Exp Ther;
303(3): 1180-8, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12438542
9.
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A): a potent and selective corticotrophin-releasing factor(1) receptor antagonist. I. Biochemical and pharmacological characterization.
J Pharmacol Exp Ther;
301(1): 322-32, 2002 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-11907190
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