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1.

Excited-State Dynamics of a Two-Photon-Activatable Ruthenium Prodrug.

Greenough, Simon E; Horbury, Michael D; Smith, Nichola A; Sadler, Peter J; Paterson, Martin J; Stavros, Vasilios G.

Chemphyschem; 17(2): 221-4, 2016 Jan 18.

Artículo en Inglés | MEDLINE | ID: mdl-26632426

2.

The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists.

Porter, David W; Bradley, Michelle; Brown, Zarin; Charlton, Steven J; Cox, Brian; Hunt, Peter; Janus, Diana; Lewis, Sarah; Oakley, Paul; O'Connor, Des; Reilly, John; Smith, Nichola; Press, Neil J.

Bioorg Med Chem Lett; 24(15): 3285-90, 2014 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-24974342

3.

Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine)2(nicotinamide)2](2+): experimental and theoretical insight into its photoactivation mechanism.

Greenough, Simon E; Roberts, Gareth M; Smith, Nichola A; Horbury, Michael D; McKinlay, Russell G; Zurek, Justyna M; Paterson, Martin J; Sadler, Peter J; Stavros, Vasilios G.

Phys Chem Chem Phys; 16(36): 19141-55, 2014 Sep 28.

Artículo en Inglés | MEDLINE | ID: mdl-25060066

4.

Synthesis of mucin-type O-glycan probes as aminopropyl glycosides.

Benito-Alifonso, David; Jones, Rachel A; Tran, Anh-Tuan; Woodward, Hannah; Smith, Nichola; Galan, M Carmen.

Beilstein J Org Chem; 9: 1867-72, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24062854

5.

Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension.

Shaw, Duncan E; Smith, Nichola; Beerli, Rene; Cotesta, Simona; D'Alessandro, Pier-Luca; Edwards, Anne-Marie; Lattmann, Rene; Lizos, Dimitrios; Pulz, Robert; Rooney, Lisa; Sohal, Bindi; Rynn, Caroline; Taylor, Jessica; Troxler, Thomas; Williams, Gareth; Guth, Sabine; Rowlands, David.

J Med Chem; 66(12): 8130-8139, 2023 06 22.

Artículo en Inglés | MEDLINE | ID: mdl-37294287

6.

Diversity-oriented synthesis encoded by deoxyoligonucleotides.

Hudson, Liam; Mason, Jeremy W; Westphal, Matthias V; Richter, Matthieu J R; Thielman, Jonathan R; Hua, Bruce K; Gerry, Christopher J; Xia, Guoqin; Osswald, Heather L; Knapp, John M; Tan, Zher Yin; Kokkonda, Praveen; Tresco, Ben I C; Liu, Shuang; Reidenbach, Andrew G; Lim, Katherine S; Poirier, Jennifer; Capece, John; Bonazzi, Simone; Gampe, Christian M; Smith, Nichola J; Bradner, James E; Coley, Connor W; Clemons, Paul A; Melillo, Bruno; Hon, C Suk-Yee; Ottl, Johannes; Dumelin, Christoph E; Schaefer, Jonas V; Faust, Ann Marie E; Berst, Frédéric; Schreiber, Stuart L; Zécri, Frédéric J; Briner, Karin.

Nat Commun; 14(1): 4930, 2023 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-37582753

7.

In Vivo Selectivity and Localization of Reactive Oxygen Species (ROS) Induction by Osmium Anticancer Complexes That Circumvent Platinum Resistance.

Coverdale, James P C; Bridgewater, Hannah E; Song, Ji-Inn; Smith, Nichola A; Barry, Nicolas P E; Bagley, Ian; Sadler, Peter J; Romero-Canelón, Isolda.

J Med Chem; 61(20): 9246-9255, 2018 10 25.

Artículo en Inglés | MEDLINE | ID: mdl-30230827

8.

Author Correction: Diversity-oriented synthesis encoded by deoxyoligonucleotides.

Hudson, Liam; Mason, Jeremy W; Westphal, Matthias V; Richter, Matthieu J R; Thielman, Jonathan R; Hua, Bruce K; Gerry, Christopher J; Xia, Guoqin; Osswald, Heather L; Knapp, John M; Tan, Zher Yin; Kokkonda, Praveen; Tresco, Ben I C; Liu, Shuang; Reidenbach, Andrew G; Lim, Katherine S; Poirier, Jennifer; Capece, John; Bonazzi, Simone; Gampe, Christian M; Smith, Nichola J; Bradner, James E; Coley, Connor W; Clemons, Paul A; Melillo, Bruno; Hon, C Suk-Yee; Ottl, Johannes; Dumelin, Christoph E; Schaefer, Jonas V; Faust, Ann Marie E; Berst, Frédéric; Schreiber, Stuart L; Zécri, Frédéric J; Briner, Karin.

Nat Commun; 14(1): 7589, 2023 Nov 21.

Artículo en Inglés | MEDLINE | ID: mdl-37989745

9.

Faith enhances, not defines practice.

Smith, Nichola.

Nurs N Z; 18(1): 4-5, 2012 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-22479999

10.

Epithelial Na⁺ channel inhibitors for the treatment of cystic fibrosis.

Smith, Nichola J; Solovay, Catherine F.

Pharm Pat Anal; 6(4): 179-188, 2017 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-28696180

11.

Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity.

Smith, Nichola A; Zhang, Pingyu; Greenough, Simon E; Horbury, Michael D; Clarkson, Guy J; McFeely, Daniel; Habtemariam, Abraha; Salassa, Luca; Stavros, Vasilios G; Dowson, Christopher G; Sadler, Peter J.

Chem Sci; 8(1): 395-404, 2017 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-28451184

12.

ENaC inhibitors for the treatment of cystic fibrosis.

Butler, Rebecca; Hunt, Thomas; Smith, Nichola J.

Pharm Pat Anal; 4(1): 17-27, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25565157

13.

Photoactivatable metal complexes: from theory to applications in biotechnology and medicine.

Smith, Nichola A; Sadler, Peter J.

Philos Trans A Math Phys Eng Sci; 371(1995): 20120519, 2013 Jul 28.

Artículo en Inglés | MEDLINE | ID: mdl-23776303

14.

Iodine-catalyzed one-pot acetalation-esterification reaction for the preparation of orthogonally protected glycosides.

Jones, Rachel A; Davidson, Robert; Tran, Anh Tuan; Smith, Nichola; Carmen Galan, M.

Carbohydr Res; 345(13): 1842-5, 2010 Sep 03.

Artículo en Inglés | MEDLINE | ID: mdl-20673882

15.

Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers.

Knutsen, Lars J S; Hobbs, Christopher J; Earnshaw, Christopher G; Fiumana, Andrea; Gilbert, Jenny; Mellor, Sarah L; Radford, Fleur; Smith, Nichola J; Birch, Philip J; Russell Burley, J; Ward, Stuart D C; James, Iain F.

Bioorg Med Chem Lett; 17(3): 662-7, 2007 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-17134896

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