1.
J Org Chem
; 71(18): 6859-62, 2006 Sep 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-16930038
RESUMEN
A variety of N-tert-butanesulfinyl imines were reduced with NaBH4 in THF containing 2% water to provide the corresponding secondary sulfinamides in high yield and diastereoselectivity. By using the same sulfinyl imine starting materials and changing the reductant to L-Selectride, the stereoselectivity could be efficiently reversed to afford the opposite product diastereomer in high yield and selectivity.