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1.

Radiation therapy-induced remodeling of the tumor immune microenvironment.

Charpentier, Maud; Spada, Sheila; Van Nest, Samantha J; Demaria, Sandra.

Semin Cancer Biol; 86(Pt 2): 737-747, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-35405340

2.

The actin modulator hMENA regulates GAS6-AXL axis and pro-tumor cancer/stromal cell cooperation.

Melchionna, Roberta; Spada, Sheila; Di Modugno, Francesca; D'Andrea, Daniel; Di Carlo, Anna; Panetta, Mariangela; Mileo, Anna Maria; Sperduti, Isabella; Antoniani, Barbara; Gallo, Enzo; Lawlor, Rita T; Piemonti, Lorenzo; Visca, Paolo; Milella, Michele; Grazi, Gian Luca; Facciolo, Francesco; Chen, Emily; Scarpa, Aldo; Nisticò, Paola.

EMBO Rep; 21(11): e50078, 2020 11 05.

Artículo en Inglés | MEDLINE | ID: mdl-32909687

3.

ß1 and ß4 integrins: from breast development to clinical practice.

Nisticò, Paola; Di Modugno, Francesca; Spada, Sheila; Bissell, Mina J.

Breast Cancer Res; 16(5): 459, 2014.

Artículo en Inglés | MEDLINE | ID: mdl-25606594

4.

Factors affecting heterogeneity in breast cancer microenvironment: A narrative mini review.

Ganguly, Anirban; Mukherjee, Sumit; Chatterjee, Kaushiki; Spada, Sheila.

Int Rev Cell Mol Biol; 385: 211-226, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38663960

5.

Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer.

Di Modugno, Francesca; Di Carlo, Anna; Spada, Sheila; Palermo, Belinda; D'Ambrosio, Lorenzo; D'Andrea, Daniel; Morello, Gaia; Belmonte, Beatrice; Sperduti, Isabella; Balzano, Vittoria; Gallo, Enzo; Melchionna, Roberta; Panetta, Mariangela; Campo, Giulia; De Nicola, Francesca; Goeman, Frauke; Antoniani, Barbara; Carpano, Silvia; Frigè, Gianmaria; Warren, Sarah; Gallina, Filippo; Lambrechts, Diether; Xiong, Jieyi; Vincent, Benjamin G; Wheeler, Nathan; Bortone, Dante S; Cappuzzo, Federico; Facciolo, Francesco; Tripodo, Claudio; Visca, Paolo; Nisticò, Paola.

EBioMedicine; 101: 105003, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38340557

6.

Methodologies to evaluate the radiation-induced changes on extracellular vesicles.

Spada, Sheila.

Methods Cell Biol; 180: 39-48, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37890931

7.

Targets of Immune Escape Mechanisms in Cancer: Basis for Development and Evolution of Cancer Immune Checkpoint Inhibitors.

Dutta, Shovan; Ganguly, Anirban; Chatterjee, Kaushiki; Spada, Sheila; Mukherjee, Sumit.

Biology (Basel); 12(2)2023 Jan 30.

Artículo en Inglés | MEDLINE | ID: mdl-36829496

8.

Quantitative assessment of mitophagy in irradiated cancer cells.

Guilbaud, Emma; Spada, Sheila; Bloy, Norma; Galassi, Claudia; Sato, Ai; Jiménez-Cortegana, Carlos; Aretz, Artur; Buqué, Aitziber; Yamazaki, Takahiro; Demaria, Sandra; Galluzzi, Lorenzo.

Methods Cell Biol; 174: 93-111, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-36710054

9.

Immunotherapy targeting different immune compartments in combination with radiation therapy induces regression of resistant tumors.

Rudqvist, Nils-Petter; Charpentier, Maud; Lhuillier, Claire; Wennerberg, Erik; Spada, Sheila; Sheridan, Caroline; Zhou, Xi Kathy; Zhang, Tuo; Formenti, Silvia C; Sims, Jennifer S; Alonso, Alicia; Demaria, Sandra.

Nat Commun; 14(1): 5146, 2023 08 24.

Artículo en Inglés | MEDLINE | ID: mdl-37620372

10.

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6^th annual ImmunoRad conference.

Gregucci, Fabiana; Spada, Sheila; Barcellos-Hoff, Mary Helen; Bhardwaj, Nina; Chan Wah Hak, Charleen; Fiorentino, Alba; Guha, Chandan; Guzman, Monica L; Harrington, Kevin; Herrera, Fernanda G; Honeychurch, Jamie; Hong, Theodore; Iturri, Lorea; Jaffee, Elisabeth; Karam, Sana D; Knott, Simon R V; Koumenis, Constantinos; Lyden, David; Marciscano, Ariel E; Melcher, Alan; Mondini, Michele; Mondino, Anna; Morris, Zachary S; Pitroda, Sean; Quezada, Sergio A; Santambrogio, Laura; Shiao, Stephen; Stagg, John; Telarovic, Irma; Timmerman, Robert; Vozenin, Marie-Catherine; Weichselbaum, Ralph; Welsh, James; Wilkins, Anna; Xu, Chris; Zappasodi, Roberta; Zou, Weiping; Bobard, Alexandre; Demaria, Sandra; Galluzzi, Lorenzo; Deutsch, Eric; Formenti, Silvia C.

Oncoimmunology; 12(1): 2222560, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37363104

11.

Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non-small cell lung cancer.

Wennerberg, Erik; Mukherjee, Sumit; Spada, Sheila; Hung, Clarey; Agrusa, Christopher J; Chen, Chuang; Valeta-Magara, Amanda; Rudqvist, Nils-Petter; Van Nest, Samantha J; Kamel, Mohamed K; Nasar, Abu; Narula, Navneet; Mittal, Vivek; Markowitz, Geoffrey J; Zhou, Xi Kathy; Adusumilli, Prasad S; Borczuk, Alain C; White, Thomas E; Khan, Abdul G; Balderes, Paul J; Lorenz, Ivo C; Altorki, Nasser; Demaria, Sandra; McGraw, Timothy E; Stiles, Brendon M.

Sci Transl Med; 14(636): eabe8195, 2022 03 16.

Artículo en Inglés | MEDLINE | ID: mdl-35294260

12.

Study of microRNAs carried by exosomes.

Spada, Sheila.

Methods Cell Biol; 165: 187-197, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-34311867

13.

Fibronectin as a multiregulatory molecule crucial in tumor matrisome: from structural and functional features to clinical practice in oncology.

Spada, Sheila; Tocci, Annalisa; Di Modugno, Francesca; Nisticò, Paola.

J Exp Clin Cancer Res; 40(1): 102, 2021 Mar 17.

Artículo en Inglés | MEDLINE | ID: mdl-33731188

14.

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.

Clement, Cristina C; D'Alessandro, Angelo; Thangaswamy, Sangeetha; Chalmers, Samantha; Furtado, Raquel; Spada, Sheila; Mondanelli, Giada; Ianni, Federica; Gehrke, Sarah; Gargaro, Marco; Manni, Giorgia; Cara, Luisa Carlota Lopez; Runge, Peter; Tsai, Wanxia Li; Karaman, Sinem; Arasa, Jorge; Fernandez-Rodriguez, Ruben; Beck, Amanda; Macchiarulo, Antonio; Gadina, Massimo; Halin, Cornelia; Fallarino, Francesca; Skobe, Mihaela; Veldhoen, Marc; Moretti, Simone; Formenti, Silvia; Demaria, Sandra; Soni, Rajesh K; Galarini, Roberta; Sardella, Roccaldo; Lauvau, Gregoire; Putterman, Chaim; Alitalo, Kari; Grohmann, Ursula; Santambrogio, Laura.

Nat Commun; 12(1): 4447, 2021 07 21.

Artículo en Inglés | MEDLINE | ID: mdl-34290243

15.

Methods to purify DNA from extracellular vesicles: Focus on exosomes.

Spada, Sheila.

Methods Enzymol; 645: 109-118, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-33565966

16.

Isolation of DNA from exosomes.

Spada, Sheila; Rudqvist, Nils-Petter; Wennerberg, Erik.

Methods Enzymol; 636: 173-183, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32178818

17.

Characterization of conventional dendritic cell populations in preclinical tumor models using flow cytometry.

Wennerberg, Erik; Rudqvist, Nils-Petter; Spada, Sheila.

Methods Enzymol; 635: 139-148, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32122542

18.

CD73 Blockade Promotes Dendritic Cell Infiltration of Irradiated Tumors and Tumor Rejection.

Wennerberg, Erik; Spada, Sheila; Rudqvist, Nils-Petter; Lhuillier, Claire; Gruber, Sylvia; Chen, Qiuying; Zhang, Fengli; Zhou, Xi K; Gross, Steven S; Formenti, Silvia C; Demaria, Sandra.

Cancer Immunol Res; 8(4): 465-478, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32047024

19.

Combination of chemotherapy and PD-1 blockade induces T cell responses to tumor non-mutated neoantigens.

Grimaldi, Alessio; Cammarata, Ilenia; Martire, Carmela; Focaccetti, Chiara; Piconese, Silvia; Buccilli, Marta; Mancone, Carmine; Buzzacchino, Federica; Berrios, Julio Rodrigo Giron; D'Alessandris, Nicoletta; Tomao, Silverio; Giangaspero, Felice; Paroli, Marino; Caccavale, Rosalba; Spinelli, Gian Paolo; Girelli, Gabriella; Peruzzi, Giovanna; Nisticò, Paola; Spada, Sheila; Panetta, Mariangela; Letizia Cecere, Fabiana; Visca, Paolo; Facciolo, Francesco; Longo, Flavia; Barnaba, Vincenzo.

Commun Biol; 3(1): 85, 2020 02 25.

Artículo en Inglés | MEDLINE | ID: mdl-32099064

20.

Detection and quantification of cytosolic DNA.

Spada, Sheila; Yamazaki, Takahiro; Vanpouille-Box, Claire.

Methods Enzymol; 629: 17-33, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31727239

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Radiation therapy-induced remodeling of the tumor immune microenvironment.

The actin modulator hMENA regulates GAS6-AXL axis and pro-tumor cancer/stromal cell cooperation.

ß1 and ß4 integrins: from breast development to clinical practice.

Factors affecting heterogeneity in breast cancer microenvironment: A narrative mini review.

Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer.

Methodologies to evaluate the radiation-induced changes on extracellular vesicles.

Targets of Immune Escape Mechanisms in Cancer: Basis for Development and Evolution of Cancer Immune Checkpoint Inhibitors.

Quantitative assessment of mitophagy in irradiated cancer cells.

Immunotherapy targeting different immune compartments in combination with radiation therapy induces regression of resistant tumors.

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6^th annual ImmunoRad conference.

Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non-small cell lung cancer.

Study of microRNAs carried by exosomes.

Fibronectin as a multiregulatory molecule crucial in tumor matrisome: from structural and functional features to clinical practice in oncology.

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.

Methods to purify DNA from extracellular vesicles: Focus on exosomes.

Isolation of DNA from exosomes.

Characterization of conventional dendritic cell populations in preclinical tumor models using flow cytometry.

CD73 Blockade Promotes Dendritic Cell Infiltration of Irradiated Tumors and Tumor Rejection.

Combination of chemotherapy and PD-1 blockade induces T cell responses to tumor non-mutated neoantigens.

Detection and quantification of cytosolic DNA.