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1.
Aust N Z J Psychiatry ; : 48674241266067, 2024 Jul 27.
Artículo en Inglés | MEDLINE | ID: mdl-39066683

RESUMEN

OBJECTIVE: To identify factors associated with receiving electroconvulsive therapy (ECT) for serious psychiatric conditions. METHODS: Retrospective observational study using hospital administrative data linked with death registrations and outpatient mental health data in New South Wales (NSW), Australia. The cohort included patients admitted with a primary psychiatric diagnosis between 2013 and 2022. The outcome measure was receipt of ECT. RESULTS: Of 94,950 patients, 3465 (3.6%) received ECT. The likelihood of receiving ECT was higher in older (hazard ratio [HR] = 1.03), female (HR = 1.24) patients. Compared to depression, patients with schizophrenia/schizoaffective disorder (HR = 0.79), schizophrenia-related disorders (HR = 0.37), mania (HR = 0.64) and other mood disorders (HR = 0.45) had lower odds of receiving ECT. Patients with depression and one other serious psychiatric condition had higher odds of receiving ECT than depression alone. Bipolar disorder likelihood of ECT did not differ from depression. A higher number of mental health outpatient visits in the prior year and an involuntary index admission with depression were also associated with receiving ECT. Likelihood of receiving ECT increased with year of admission (HR = 1.32), private patient status (HR = 2.06), higher socioeconomic status (HR = 1.09) and being married (HR = 1.25). CONCLUSIONS: ECT use for depression and bipolar disorder in NSW aligns with clinical national guidelines. Patients with schizophrenia/schizoaffective, schizophrenia-related disorders, mania and other mood disorders had lower likelihood of ECT than depression, despite ECT being recommended by clinical guidelines for these diagnoses. Variations in ECT were strongly associated with healthcare access, with private patients twice as likely to receive ECT than their public counterparts, suggesting a need to explore ECT accessibility.

2.
Aust N Z J Psychiatry ; 57(6): 844-853, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-35920253

RESUMEN

OBJECTIVE: Little research has examined the physical and mental comorbidities, and health service use patterns, of people diagnosed with psychotic disorder subtypes other than schizophrenia spectrum disorders. This study aims to examine the physical and mental comorbidities, and subsequent hospital service use patterns, of individuals previously hospitalised with various psychotic disorder subtypes using linked health service data. METHODS: We included individuals hospitalised with a psychotic disorder in New South Wales, Australia, between 1 July 2002 and 31 December 2014 (N = 63,110). We examined the demographic profile of the cohort and rates of subsequent acute hospital care and ambulatory mental health service use. We compared the rates of subsequent hospital admissions, emergency department presentations and ambulatory mental health treatment days of people hospitalised with different psychotic disorder subtypes to people hospitalised with schizophrenia spectrum disorders using Poisson regression. RESULTS: People most recently hospitalised with mood/affective disorders and psychotic symptoms had a higher rate of subsequent hospital admissions than those most recently hospitalised with schizophrenia spectrum and delusional disorders (adjusted incident rate ratio = 1.06; 95% confidence interval = [1.02, 1.10]), while people most recently hospitalised with drug-induced and other organic (adjusted incident rate ratio = 1.19; 95% confidence interval = [1.12, 1.27]) and acute psychotic disorders (adjusted incident rate ratio = 1.10; 95% confidence interval = [1.03, 1.18]) had more subsequent emergency department presentations than those most recently hospitalised with schizophrenia spectrum and delusional disorders. All three groups had fewer subsequent mental health ambulatory days than those most recently hospitalised with schizophrenia spectrum and delusional disorders (adjusted incident rate ratios = 0.85-0.91). CONCLUSION: The health profiles and subsequent hospital service use patterns of people previously hospitalised with different psychotic disorder subtypes are heterogeneous, and research is needed to develop targeted health policies to meet their specific health needs.


Asunto(s)
Servicios de Salud Mental , Trastornos Psicóticos , Esquizofrenia , Humanos , Trastornos Psicóticos/epidemiología , Trastornos Psicóticos/terapia , Trastornos Psicóticos/diagnóstico , Esquizofrenia/epidemiología , Esquizofrenia/terapia , Salud Mental , Hospitales
3.
Alzheimers Dement ; 19(11): 5138-5150, 2023 11.
Artículo en Inglés | MEDLINE | ID: mdl-37126409

RESUMEN

INTRODUCTION: People living with dementia experience poor mental health and high rates of self-harm. We investigated risk factors for self-harm in people aged > 40 years living with dementia and risk factors for dementia after self-harm. METHODS: Using linked hospital data from New South Wales, Australia, we defined a dementia cohort (n = 154,811) and a self-harm cohort (n = 28,972). Using survival analyses, we investigated predictors of self-harm for the dementia cohort, and predictors of dementia for the self-harm cohort. RESULTS: We found self-harm or dementia diagnoses occurred most often within 24 months of a dementia diagnosis or initial self-harm presentation, respectively. Men living with dementia, and people with complex psychiatric profiles, had the greatest risk of self-harm. Men who had self-harmed had the greatest risk of dementia diagnoses. DISCUSSION: Men and people with complex psychiatric profiles and dementia may particularly benefit from post-diagnosis mental and behavioral support to reduce risk of self-harm.


Asunto(s)
Demencia , Conducta Autodestructiva , Masculino , Humanos , Conducta Autodestructiva/epidemiología , Conducta Autodestructiva/etiología , Factores de Riesgo , Australia , Demencia/epidemiología
4.
Aust N Z J Psychiatry ; 56(6): 675-685, 2022 06.
Artículo en Inglés | MEDLINE | ID: mdl-34256621

RESUMEN

OBJECTIVE: To describe and compare the health profiles and health service use of people hospitalised with severe mental illness, with and without psychotic symptoms. METHODS: We conducted a historical cohort study using linked administrative datasets, including data on public hospital admissions, emergency department presentations and ambulatory mental health service contacts in New South Wales, Australia. The study cohort comprised 169,306 individuals aged 12 years and over who were hospitalised at least once with a mental health diagnosis between 1 July 2002 and 31 December 2014. Of these, 63,110 had a recorded psychotic illness and 106,196 did not. Outcome measures were rates of hospital, emergency department and mental health ambulatory service utilisation, analysed using Poisson regression. RESULTS: People with psychotic illnesses had higher rates of hospital admission (adjusted incidence rate ratio (IRR) 1.26; 95% confidence interval [1.23, 1.30]), emergency department presentation (adjusted IRR 1.17; 95% confidence interval [1.13, 1.20]) and ambulatory mental health treatment days (adjusted IRR 2.90; 95% confidence interval [2.82, 2.98]) than people without psychotic illnesses. The higher rate of hospitalisation among people with psychotic illnesses was driven by mental health admissions; while people with psychosis had over twice the rate of mental health admissions, people with other severe mental illnesses without psychosis (e.g. mood/affective, anxiety and personality disorders) had higher rates of physical health admissions, including for circulatory, musculoskeletal, genitourinary and respiratory disorders. Factors that predicted greater health service utilisation included psychosis, intellectual disability, greater medical comorbidity and previous hospitalisation. CONCLUSION: Findings from this study support the need for (a) the development of processes to support the physical health of people with severe mental illness, including those without psychosis; (b) a focus in mental health policy and service provision on people with complex support needs, and (c) improved implementation and testing of integrated models of care to improve health outcomes for all people experiencing severe mental illness.


Asunto(s)
Discapacidad Intelectual , Servicios de Salud Mental , Trastornos Psicóticos , Australia , Estudios de Cohortes , Humanos , Discapacidad Intelectual/epidemiología , Nueva Gales del Sur/epidemiología , Trastornos Psicóticos/diagnóstico , Trastornos Psicóticos/epidemiología , Trastornos Psicóticos/terapia
5.
Med J Aust ; 215(1): 31-36, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-34028026

RESUMEN

OBJECTIVE: To determine rates of potentially preventable hospitalisation of people with intellectual disability in New South Wales, and compare them with those for the NSW population. DESIGN: Retrospective cohort study. SETTING: Potentially preventable hospitalisations in NSW, as defined by the National Healthcare Agreement progress indicator 18, 1 July 2001 - 30 June 2015. PARTICIPANTS: Data collected in a retrospective data linkage study of 92 542 people with intellectual disability in NSW; potentially preventable hospitalisations data for NSW published by HealthStats NSW. MAIN OUTCOME MEASURES: Age-adjusted rates of potentially preventable hospitalisation by group (people with intellectual disability, NSW population), medical condition type (acute, chronic, vaccine-preventable), and medical condition. RESULTS: The annual age-standardised rate for people with intellectual disability ranged between 5286 and 6301 per 100 000 persons, and for the NSW population between 1278 and 1511 per 100 000 persons; the rate ratio (RR) ranged between 3.5 (95% CI, 3.3-3.7) in 2014-15 and 4.5 (95% CI, 4.2-4.9) in 2002-03. The difference was greatest for admissions with acute (RR range: 5.3 [95% CI, 4.9-5.7] in 2014-15 to 8.1 [95% CI, 7.4-8.8] in 2002-03) and vaccine-preventable conditions (RR range: 2.1 [95% CI, 1.6-3.0] in 2007-08 to 3.4 [95% CI, 2.2-5.2] in 2004-05). By specific condition, the highest age-standardised rate was for admissions with convulsions and epilepsy (all years, 2567 per 100 000 population; v NSW population: RR, 22.2; 95% CI, 21.3-23.1). CONCLUSION: Age-standardised rates of potentially preventable hospitalisation are higher for people with intellectual disability than for the general population. The reasons for these differences should be investigated, and strategies for averting potentially preventable hospitalisation developed.


Asunto(s)
Hospitalización/estadística & datos numéricos , Personas con Discapacidades Mentales/estadística & datos numéricos , Enfermedad Aguda/terapia , Adolescente , Adulto , Anciano , Niño , Preescolar , Enfermedad Crónica/terapia , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Persona de Mediana Edad , Nueva Gales del Sur/epidemiología , Estudios Retrospectivos , Adulto Joven
6.
Med J Aust ; 215(7): 325-331, 2021 Oct 04.
Artículo en Inglés | MEDLINE | ID: mdl-34227120

RESUMEN

OBJECTIVES: To describe the population characteristics of people with intellectual disability in New South Wales; to quantify and compare public mental health service use and costs for people with and without intellectual disability in NSW during 2014-15. DESIGN: Retrospective cohort data linkage analysis. SETTING, PARTICIPANTS: People using publicly funded in- or outpatient (admitted or non-admitted) mental health services in NSW, 2014-15. MAIN OUTCOME MEASURES: Numbers of bed days (inpatient mental health services), and treatment days (ambulatory mental health); costs of publicly funded mental health services. RESULTS: People with intellectual disability comprised 1.1% of the NSW population, but 6.3% of people who used public mental health services; 12% of public mental health costs during 2014-15 were for people with intellectual disability. Compared with metropolitan local health districts (LHDs), overall public mental health service costs were lower for rural and regional LHDs (adjusted incidence rate ratio [aIRR], 0.8; 95% CI, 0.8-0.9) and higher for specialty networks (aIRR, 1.2; 95% CI, 1.1-1.3). Per person costs for people with intellectual disability were higher than for those without intellectual disability (aIRR, 2.6; 95% CI, 2.2-3.0). CONCLUSION: People with intellectual disability use public mental health services to a greater degree than other people. They should be explicitly considered by all tiers of mental health policy and service planning in Australia. Population health planning for the needs of people with disabilities would be assisted by including disability identifiers in all health administrative data sets.


Asunto(s)
Costos de la Atención en Salud/estadística & datos numéricos , Discapacidad Intelectual/epidemiología , Servicios de Salud Mental/economía , Aceptación de la Atención de Salud/estadística & datos numéricos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Atención Ambulatoria/economía , Atención Ambulatoria/estadística & datos numéricos , Niño , Preescolar , Estudios de Cohortes , Femenino , Hospitalización/economía , Hospitalización/estadística & datos numéricos , Humanos , Incidencia , Lactante , Recién Nacido , Almacenamiento y Recuperación de la Información , Discapacidad Intelectual/economía , Masculino , Persona de Mediana Edad , Nueva Gales del Sur/epidemiología , Evaluación de Resultado en la Atención de Salud , Estudios Retrospectivos , Población Rural/estadística & datos numéricos , Adulto Joven
7.
J Pediatr ; 217: 131-138.e10, 2020 02.
Artículo en Inglés | MEDLINE | ID: mdl-31812294

RESUMEN

OBJECTIVE: To examine the frequency of hospital admissions before and after gastrostomy insertion in children with severe intellectual disability. STUDY DESIGN: We conducted a retrospective cohort study using linked health administrative and disability data from Western Australia (WA) and New South Wales (NSW). Children born between 1983 and 2009 in WA and 2002 and 2010 in NSW who had a gastrostomy insertion performed (n = 673 [WA, n = 325; NSW, n = 348]) by the end of 2014 (WA) and 2015 (NSW) were included. Conditional Poisson regression models were used to evaluate the age-adjusted effect of gastrostomy insertion on acute hospitalizations for all-cause, acute lower respiratory tract infections (LRTI), and epilepsy admissions. RESULTS: The incidence of all-cause hospitalizations declined at 5 years after procedure (WA cohort 1983-2009: incidence rate ratio, 0.70 [95% CI, 0.60-0.80]; WA and NSW cohort 2002-2010: incidence rate ratio, 0.63 [95% CI, 0.45-0.86]). Admissions for acute LRTI increased in the WA cohort and remained similar in the combined cohort. Admissions for epilepsy decreased 4 years after gastrostomy in the WA cohort and were generally lower in the combined cohort. Fundoplication seemed to decrease the relative incidence of acute LRTI admissions in the combined cohort. CONCLUSIONS: Gastrostomy was associated with health benefits including reduced all-cause and epilepsy hospitalizations, but was not protective against acute LRTI. These decreases in hospitalizations may reflect improved delivery of nutrition and medications.


Asunto(s)
Gastrostomía/métodos , Hospitalización/estadística & datos numéricos , Discapacidad Intelectual/terapia , Niño , Preescolar , Femenino , Estudios de Seguimiento , Humanos , Lactante , Discapacidad Intelectual/epidemiología , Masculino , Morbilidad/tendencias , Nueva Gales del Sur/epidemiología , Periodo Posoperatorio , Estudios Retrospectivos , Factores de Riesgo , Factores de Tiempo , Australia Occidental/epidemiología
8.
J Appl Res Intellect Disabil ; 33(3): 420-429, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-31786826

RESUMEN

BACKGROUND: People with intellectual disability (ID) experience higher mortality than the general population. This study examines factors contributing to deaths in people with intellectual disability. METHOD: Linked administrative data spanning ten years for 49,947 people with intellectual disability receiving disability services were analysed to assess the impact of demographic variables, comorbidities and health service utilization on the risk of death using Cox proportional hazard models. RESULTS: People admitted for cancer were 8 times more likely to die within the study period compared to people not admitted for cancer. Down syndrome, cerebral palsy and heart disease also increased the risk of death. Emergency department presentations and/or mental health admissions increased the risk of death 4 times. CONCLUSIONS: Our findings provide a basis for policy changes and public health interventions. Cancer screening, mental health interventions, inclusion of people with intellectual disability in health policy and improved health care are needed to meet the needs of this population.


Asunto(s)
Causas de Muerte , Parálisis Cerebral/epidemiología , Cardiopatías/epidemiología , Discapacidad Intelectual/epidemiología , Neoplasias/epidemiología , Aceptación de la Atención de Salud/estadística & datos numéricos , Personas con Discapacidades Mentales/estadística & datos numéricos , Sistema de Registros , Adolescente , Adulto , Anciano , Parálisis Cerebral/mortalidad , Niño , Preescolar , Comorbilidad , Conjuntos de Datos como Asunto , Síndrome de Down/epidemiología , Femenino , Cardiopatías/mortalidad , Humanos , Lactante , Masculino , Persona de Mediana Edad , Neoplasias/mortalidad , Modelos de Riesgos Proporcionales , Riesgo , Adulto Joven
9.
J Appl Res Intellect Disabil ; 33(6): 1357-1367, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32864851

RESUMEN

BACKGROUND: Can disability support services (DS) facilitate access to mental health services (MHS) for people with intellectual disability? This study utilized 10 years of data from 6,260 persons in NSW who had received DS and specific MHS to quantify the relationship between DS utilization and MHS utilization in adults with intellectual disability and co-existing mental illness. RESULTS: Receipt of DS was associated with greater odds of accessing community mental health (CMH) services (36%, 95% CI 29%-43%) but not psychiatric admissions. Age, sex and social disadvantage did not affect the odds of psychiatric admission or CMH use. Individuals living in a remote area had greater odds of CMH use and lesser odds of psychiatric admission. CONCLUSIONS: Receipt of DS was associated with greater CMH but not psychiatric hospital utilization in people with intellectual disability and co-existing mental illness.


Asunto(s)
Servicios Comunitarios de Salud Mental , Discapacidad Intelectual , Trastornos Mentales , Servicios de Salud Mental , Adulto , Utilización de Instalaciones y Servicios , Hospitales Psiquiátricos , Humanos , Discapacidad Intelectual/epidemiología , Discapacidad Intelectual/terapia , Trastornos Mentales/epidemiología , Trastornos Mentales/terapia
10.
Eur J Pediatr ; 178(3): 351-361, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-30554367

RESUMEN

The largest group of recipients of pediatric gastrostomy have neurological impairment with intellectual disability (ID). This study investigated trends in first gastrostomy insertion according to markers of disadvantage and ID etiology. Linked administrative and health data collected over a 32-year study period (1983-2014) for children with ID born between 1983 and 2009 in Western Australia were examined. The annual incidence rate change over calendar year was calculated for all children and according to socioeconomic status, geographical remoteness, and Aboriginality. The most likely causes of ID were identified using available diagnosis codes in the linked data set. Of 11,729 children with ID, 325 (2.8%) received a first gastrostomy within the study period. The incidence rate was highest in the 0-2 age group and there was an increasing incidence trend with calendar time for each age group under 6 years of age. This rate change was greatest in children from the lowest socioeconomic status quintile, who lived in regional/remote areas or who were Aboriginal. The two largest identified groups of ID were genetically caused syndromes (15.1%) and neonatal encephalopathy (14.8%).Conclusion: Gastrostomy is increasingly used in multiple neurological conditions associated with ID, with no apparent accessibility barriers in terms of socioeconomic status, remoteness, or Aboriginality. What is Known: • The use of gastrostomy insertion in pediatrics is increasing and the most common recipients during childhood have neurological impairment, most of whom also have intellectual disability (ID). What is New: • Nearly 3% of children with ID had gastrostomy insertion performed, with the highest incidence in children under 3 years of age. • Gastrostomy use across different social groups was equitable in the Australian setting.


Asunto(s)
Gastrostomía/tendencias , Disparidades en Atención de Salud/tendencias , Discapacidad Intelectual/cirugía , Pautas de la Práctica en Medicina/tendencias , Adolescente , Niño , Preescolar , Femenino , Gastrostomía/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/tendencias , Disparidades en Atención de Salud/estadística & datos numéricos , Humanos , Lactante , Recién Nacido , Discapacidad Intelectual/diagnóstico , Discapacidad Intelectual/epidemiología , Discapacidad Intelectual/etiología , Estudios Longitudinales , Masculino , Pautas de la Práctica en Medicina/estadística & datos numéricos , Estudios Retrospectivos , Australia Occidental/epidemiología
11.
J Pediatr Gastroenterol Nutr ; 67(5): e89-e94, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-29851763

RESUMEN

OBJECTIVE: Gastrostomy insertion in pediatrics is usually used in children with complex needs and severe disability. The accessibility and acceptance of the procedure is increasing but population-based occurrence data are lacking and there is limited understanding of its use in clinical subgroups. METHODS: This birth cohort study investigated the trends in first gastrostomy insertion among a pediatric population born between 1983 and 2009 in Western Australia using linked administrative and health data collected over a 32-year period (1983-2014). Indications were identified using diagnosis codes from linked hospitalization data and grouped according to a refined classification system. Age and birth cohort patterns of first gastrostomy use, over calendar year and age respectively, were described. RESULTS: Of the 690,688 children born between 1983 and 2009, 466 underwent a gastrostomy insertion. Overall, the prevalence was approximately 7 cases per 10,000 births. New gastrostomy insertions were increasingly performed in children during the preschool years over calendar years and in successive birth cohorts. Children with a neurological disorder constituted the largest group receiving gastrostomy (n = 372; 79.8) including 325 (87.4%) with comorbid intellectual disability. CONCLUSIONS: New gastrostomy insertion among children who require long-term enteral feeding support increased over the study period. The procedure is most often performed in the context of severe neurological disability, including intellectual disability, and offers families potential for long-term home-based management of feeding difficulties.


Asunto(s)
Nutrición Enteral/tendencias , Gastrostomía/tendencias , Pediatría/tendencias , Adolescente , Niño , Preescolar , Femenino , Hospitalización/estadística & datos numéricos , Humanos , Lactante , Recién Nacido , Discapacidad Intelectual/terapia , Estudios Longitudinales , Masculino , Enfermedades del Sistema Nervioso/terapia , Prevalencia , Australia Occidental/epidemiología
13.
BMC Palliat Care ; 17(1): 1, 2017 Jun 21.
Artículo en Inglés | MEDLINE | ID: mdl-28637450

RESUMEN

BACKGROUND: There is limited population-level research on end-of-life care in Australia that considers health care use and costs across hospital and community sectors. The aim of this study was to quantify health care use and costs in the last 6 months of life in a cohort of elderly Australian decedents and to examine the factors associated with end-of-life resource use and costs. METHODS: A retrospective cohort study using routinely collected health data from Australian Government Department of Veterans' Affairs clients. The study included two cohorts of elderly Australians who died between 2005 and 2009; one cohort with a recorded cancer diagnosis and a comparison cohort with no evidence of a cancer history. We examined hospitalisations, emergency department (ED) visits, prescription drugs, clinician visits, pathology, and procedures and associated costs in the last 6 months of life. We used negative binominal regression to explore factors associated with health service use and costs. RESULTS: The cancer cohort had significantly higher rates of health service use and 27% higher total health care costs than the comparison cohort; in both cohorts, costs were driven primarily by hospitalisations. Older age was associated with lower costs and those who died in residential aged care incurred half the costs of those who died in hospital. CONCLUSIONS: The results suggest differences in end-of-life care pathways dependent on patient factors, with younger, community-dwelling patients and those with a history of cancer incurring significantly greater costs. There is a need to examine whether the investment in end-of-life care meets patient and societal needs.


Asunto(s)
Atención a la Salud/economía , Atención a la Salud/estadística & datos numéricos , Neoplasias/terapia , Cuidado Terminal/economía , Anciano , Anciano de 80 o más Años , Australia , Estudios de Cohortes , Análisis Costo-Beneficio , Femenino , Costos de la Atención en Salud , Humanos , Masculino , Neoplasias/economía , Estudios Retrospectivos , Cuidado Terminal/métodos , Cuidado Terminal/normas
14.
Br J Cancer ; 114(11): 1293-302, 2016 05 24.
Artículo en Inglés | MEDLINE | ID: mdl-27115468

RESUMEN

BACKGROUND: There is growing interest in end-of-life care in cancer patients. We aim to characterise health service use and costs in decedents with cancer history and examine factors associated with resource use and costs at life's end. METHODS: We used routinely collected claims data to quantify health service use and associated costs in two cohorts of elderly Australians diagnosed with cancer: one cohort died from cancer (n=4271) and the other from non-cancer causes (n=3072). We used negative binomial regression to examine the factors associated with these outcomes. RESULTS: Those who died from cancer had significantly higher rates of hospitalisations and medicine use but lower rates of emergency department use than those who died from non-cancer causes. Overall health care costs were significantly higher in those who died from cancer than those dying from other causes; and 40% of costs were expended in the last month of life. CONCLUSIONS: We analysed health services use and costs from a payer perspective, and highlight important differences in patterns of care by cause of death in patients with a cancer history. In particular, there are growing numbers of highly complex patients approaching the end of life and the heterogeneity of these populations may present challenges for effective health service delivery.


Asunto(s)
Costos de la Atención en Salud/estadística & datos numéricos , Servicios de Salud/economía , Neoplasias/economía , Cuidado Terminal/economía , Anciano , Anciano de 80 o más Años , Australia , Causas de Muerte , Estudios de Cohortes , Atención a la Salud , Costos de los Medicamentos/estadística & datos numéricos , Servicio de Urgencia en Hospital/economía , Servicio de Urgencia en Hospital/estadística & datos numéricos , Femenino , Servicios de Salud/estadística & datos numéricos , Cuidados Paliativos al Final de la Vida/economía , Hospitalización/economía , Hospitalización/estadística & datos numéricos , Humanos , Masculino , Neoplasias/mortalidad , Neoplasias/terapia , Visita a Consultorio Médico/economía , Visita a Consultorio Médico/estadística & datos numéricos
15.
Pharmacoepidemiol Drug Saf ; 24(6): 600-9, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25858166

RESUMEN

PURPOSE: We assessed the impact of a cancer diagnosis and its timing on antidepressant initiation. We also examined patterns of, and factors associated with, new antidepressant treatment in cancer patients. METHODS: We followed 61 067 antidepressant-naive Australian Government Department of Veterans' Affairs clients. We used multivariable Cox proportional hazards models with time-varying covariates to compare antidepressant initiation in clients with and without cancer and to assess how initiation varies with time from diagnosis, adjusting for sociodemographic characteristics, health service use and co-morbidities. RESULTS: 17.2% (995/5795) of cancer patients initiated antidepressants and, on average, was more likely to initiate treatment than non-cancer controls with similar characteristics (initiation rate 9/100 person-years, 95% confidence interval: 8.5-9.6 vs 6.6/100 person-years, 95% confidence interval: 6.5-6.7). The peak initiation period was 12 weeks before and 16 weeks after diagnosis; cancer patients were 42% more likely to commence therapy than non-cancer patients (adjusted hazard ratio = 1.4, 1.2 to 1.7). Cancer patients with co-morbid disease, dispensed opioids, corticosteroids or anxiolytics and to whom death was approaching were more likely to initiate treatment. Median duration of antidepressant therapy was 16 weeks. CONCLUSION: New antidepressant treatment is more common in cancer populations than in cancer-free populations. Treatment was most commonly initiated around diagnosis time, a period when cancer drug treatments also commence. The timing of peak antidepressant uptake suggests treatment may be for short-term adjustment reactions, better managed without drugs. Durations of treatment are shorter than recommended for depression.


Asunto(s)
Antidepresivos/uso terapéutico , Trastorno Depresivo/tratamiento farmacológico , Neoplasias , Anciano , Anciano de 80 o más Años , Antidepresivos/administración & dosificación , Antineoplásicos/administración & dosificación , Australia/epidemiología , Esquema de Medicación , Femenino , Humanos , Masculino , Neoplasias/tratamiento farmacológico , Neoplasias/psicología , Modelos de Riesgos Proporcionales , Factores Socioeconómicos , Veteranos
16.
Int J Cancer ; 135(9): 2146-56, 2014 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-24639369

RESUMEN

There are limited data characterizing the subtype-specific incidence of lymphoid neoplasms in the World Health Organization (WHO) Classification era. Data were obtained on all incident lymphoid neoplasms registered in Australia during 1982-2006. Subtypes were grouped using the InterLymph nested hierarchical classification, based on the 2008 WHO Classification. Temporal trends were examined using Joinpoint regression; average annual percentage change in incidence was computed. Multiple Poisson regression was used to compare incidence by sex and age. The incidence of all non-Hodgkin lymphoma (NHL) increased by 2.5%/year during 1982-1996 and was stable thereafter. During 1997-2006, several mature B- and natural killer (NK)-/T-cell NHL subtypes increased in incidence, including diffuse large B-cell (1.3%/year), follicular (2.5%/year), Burkitt (6.8%/year), marginal zone (13.2%/year), mantle cell (4.2%/year), peripheral T-cell lymphoma (4.7%/year) and plasmacytoma (7.1%/year). While chronic lymphocytic leukemia incidence was stable, small lymphocytic lymphoma incidence declined (8.1%/year). Hodgkin lymphoma (HL) incidence increased during 1997-2006 (2.2%/year), both classical (4.3%/year) and nodular lymphocyte predominant (12.1%/year) HL. Diagnostic artifact, evidenced by a sustained decline in the incidence of NHL not otherwise specified (NOS; 5.8%/year) and lymphoid neoplasms NOS (5.6%/year), limits the interpretation of temporal trends for some subtypes. A marked male predominance was observed for almost all subtypes. Incidence of mature B- and NK-/T-cell NHL subtypes increased sharply with age, except for Burkitt lymphoma/leukemia. For HL subtypes, a bimodal age distribution was only evident for nodular sclerosis HL. Variation in incidence patterns over time and by sex and age supports etiological differences between lymphoid neoplasm subtypes.


Asunto(s)
Linfoma/clasificación , Linfoma/epidemiología , Adolescente , Adulto , Factores de Edad , Anciano , Australia/epidemiología , Niño , Preescolar , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Lactante , Recién Nacido , Masculino , Persona de Mediana Edad , Pronóstico , Factores Sexuales , Factores de Tiempo , Organización Mundial de la Salud , Adulto Joven
17.
Epidemiol Health ; : e2024054, 2024 Jun 12.
Artículo en Inglés | MEDLINE | ID: mdl-38901827

RESUMEN

This cohort profile describes one of the largest linked datasets in the world concerning the health of people with intellectual disability. The cohort comprises a retrospective group of 100,089 individuals with intellectual disability who received disability and/or health services in New South Wales, Australia. Of these participants, 34% were female, with a median age at cohort entry of 3 years (interquartile range, 0 to 19 years). A separate comparator cohort included 455,677 individuals, matched by 5-year age group, sex, and residential postcode at a 5:1 ratio. Initial results indicate that between 2001 and 2018, people with intellectual disability experienced more than double the rate of hospitalisations (538 versus 235 per 1000 person-years), as well as markedly higher rates of emergency department presentations (707 versus 379 per 1000 person-years) and use of ambulatory mental health services (1012 versus 157 per 1000 person-years), relative to the comparator cohort. The largest disparities in hospital admissions were for mental disorders, dialysis, and diseases of the nervous system and sense organs. Furthermore, individuals with intellectual disability had more than double the rate of dispensed medications found in the comparator cohort. Of these medications, 46.6% were for the treatment of nervous system conditions, as opposed to 24.7% for the comparator cohort. The mean age at death was 52 years (standard deviation [SD], 19 years) for people with intellectual disability and 64 years (SD, 22 years) for the comparator participants.

18.
BMJ Ment Health ; 27(1)2024 Mar 27.
Artículo en Inglés | MEDLINE | ID: mdl-38538031

RESUMEN

BACKGROUND: Mental health services are available for young people involved with the criminal justice system. However, they have unmet mental health needs after the expiration of criminal justice supervision. OBJECTIVE: To determine the incidence rate and identify predictors of psychiatric hospitalisations within 24 months after the expiration of criminal justice supervision among young people involved with the New South Wales (NSW) criminal justice system. METHODS: Retrospective data from 1556 individuals aged 14-22 years who participated in four surveys of justice-involved young people in NSW were harmonised and linked to four NSW data collections. We calculated the incidence rates of psychiatric hospitalisations within 24 months postsupervision and identified predictors of these hospitalisations using a competing risks regression analysis. RESULTS: Within 24 months postsupervision, 11.4% had a psychiatric hospitalisation compared with 3.5% during supervision. 20.7% of those admitted had a known history of mental illness and engaged with community-based and outpatient mental health services postsupervision. Predictors of psychiatric hospitalisations were: female sex (adjusted subdistribution HR (asHR) 1.84, 95% CI 1.24 to 2.73); previous incarceration (highest asHR for ≥4 episodes 1.67, 95% CI 1.01 to 2.78); head injury (asHR 1.63, 95% CI 1.20 to 2.21); personality disorder (asHR 3.66, 95% CI 2.06 to 6.48) and alcohol and substance use disorder (asHR 1.89, 95% CI 1.29 to 2.77). CONCLUSION: Justice-involved youth have higher rates of psychiatric admissions after criminal justice supervision. Engagement with mental health services postsupervision is important in addressing emerging or persisting mental health needs.


Asunto(s)
Derecho Penal , Trastornos Relacionados con Sustancias , Adolescente , Humanos , Femenino , Estudios Retrospectivos , Trastornos Relacionados con Sustancias/epidemiología , Hospitalización , Australia/epidemiología
19.
J Psychiatr Res ; 164: 51-58, 2023 08.
Artículo en Inglés | MEDLINE | ID: mdl-37315354

RESUMEN

BACKGROUND: Premature mortality in people with mental illness is well-documented, yet deaths during inpatient psychiatric care have received little research attention. This study investigates mortality rates and causes of death during inpatient psychiatric care in New South Wales (NSW), Australia. Risk factors for inpatient death were also explored. METHODS: A retrospective cohort study using linked administrative datasets with complete capture of psychiatric admissions in NSW from 2002 to 2012 (n = 421,580) was conducted. Univariate and multivariate random-effects logistic regression analyses were used to explore risk factors for inpatient death. RESULTS: The mortality rate during inpatient psychiatric care was 1.12 deaths per 1000 episodes of care and appeared to decline over the study period. Suicide accounted for 17% of inpatient deaths, while physical health causes accounted for 75% of all deaths. Thirty percent of these deaths were considered potentially avoidable. In the multivariate model, male sex, unknown address and several physical health diagnoses were associated with increased deaths. CONCLUSIONS: The mortality rate and number of avoidable deaths during inpatient psychiatric care were substantial and warrant further systemic investigation. This was driven by a dual burden of physical health conditions and suicide. Strategies to improve access to physical health care on psychiatric inpatient wards and prevent inpatient suicide are necessary. A coordinated approach to monitoring psychiatric inpatient deaths in Australia is not currently available and much needed.


Asunto(s)
Pacientes Internos , Web Semántica , Humanos , Masculino , Nueva Gales del Sur/epidemiología , Estudios Retrospectivos , Causas de Muerte , Australia
20.
BJPsych Open ; 9(2): e44, 2023 Feb 27.
Artículo en Inglés | MEDLINE | ID: mdl-36847167

RESUMEN

BACKGROUND: Prisoners with an intellectual disability are overrepresented in custody and more likely to reoffend and be reincarcerated compared with the general prison population. Although prisoners with intellectual disability have many of the same risk factors for recidivism as the general prison population, the high rates of mental illness experienced by this group are key drivers of recidivism. AIMS: We aimed to assess the impact of provision of post-release disability and community mental health support on rates of reincarceration in a cohort with identified intellectual disability and serious mental illness diagnosis. METHOD: We conducted a historical cohort study using linked administrative data-sets, including data on hospital admissions, community mental health, disability support and corrections custody in New South Wales, Australia (n = 484). To assess the time to return to adult custody, we used survival analysis on multiple failure-time data. RESULTS: Over the median follow-up period of 7.4 years, 73.7% (357) received community mental health support, 19.8% (96) received disability support and 18.6% (85) received a combination of supports during a post-release period from prison. Lower hazards of reincarceration in a post-release period were associated with receipt of community mental health support (hazard ratio [HR] = 0.58, CI 0.49-0.69, P < 0.001), or a combination of community mental health and disability support (HR = 0.46, CI 0.34-0.61, P < 0.001). CONCLUSIONS: High rates of reincarceration for prisoners with intellectual disability and history of serious mental illness may be modifiable by provision of appropriate mental health and disability supports.

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