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1.
Nonclinical toxicology development of a novel antibody antibiotic conjugate for treating invasive Staphylococcus Aureus infections.
Toxicol Appl Pharmacol;
435: 115811, 2022 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34896194
2.
Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy.
Toxicol Appl Pharmacol;
421: 115534, 2021 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33852878
3.
Predictivity/Translatability of Toxicities Observed in Nonclinical Toxicology Studies to Clinical Safety Outcomes in Drug Development: Case Examples.
Int J Toxicol;
39(2): 141-150, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31875744
4.
Antibody-Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo.
Bioconjug Chem;
30(5): 1356-1370, 2019 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30966735
5.
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates.
Mol Pharm;
15(9): 3979-3996, 2018 09 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30040421
6.
Peripheral neuropathy with microtubule inhibitor containing antibody drug conjugates: Challenges and perspectives in translatability from nonclinical toxicology studies to the clinic.
Regul Toxicol Pharmacol;
82: 1-13, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27773754
7.
An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.
Mol Pharm;
12(6): 1717-29, 2015 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25853436
8.
Workshop proceedings: challenges and opportunities in evaluating protein allergenicity across biotechnology industries.
Int J Toxicol;
32(1): 4-10, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23324160
9.
Acute and 28-day repeated dose toxicology studies in mice with aryloxyalkanoate dioxygenase (AAD-1) protein expressed in 2,4-D tolerant DAS-40278-9 maize.
Regul Toxicol Pharmacol;
62(2): 363-70, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22100718
10.
Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids.
Anesthesiology;
114(4): 940-8, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21386701
11.
Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain.
Eur J Neurosci;
29(4): 727-37, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19200067
12.
Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.
Cancer Cell;
31(3): 383-395, 2017 03 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28262555
13.
Autolytic degradation of skipjack tuna during heating as affected by initial quality and processing conditions.
J Food Sci;
77(2): C149-55, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22250749
14.
Assessment of possible carcinogenicity of oxyfluorfen to humans using mode of action analysis of rodent liver effects.
Toxicol Sci;
128(2): 334-45, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22539621
15.
CB2 cannabinoid receptor mediation of antinociception.
Pain;
122(1-2): 36-42, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16563625
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