Detalles de la búsqueda
1.
Performance and Sensitivity of [99mTc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver.
Mol Pharm;
21(2): 932-943, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38225758
2.
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs.
Antimicrob Agents Chemother;
67(3): e0149322, 2023 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36786609
3.
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice.
Int J Mol Sci;
23(12)2022 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35742960
4.
Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharm Res;
38(1): 127-140, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33559045
5.
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model.
Int J Mol Sci;
21(21)2020 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33153231
6.
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
Mol Pharm;
16(3): 1282-1293, 2019 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30694684
7.
Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[11 C]verapamil in elderly vs. young subjects.
Br J Clin Pharmacol;
83(9): 1991-1999, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28401570
8.
Design, Synthesis, and Evaluation of a Low-Molecular-Weight (11)C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry.
Bioconjug Chem;
27(7): 1707-12, 2016 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27308894
9.
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-ß-d-allofuranosyl)-2-nitroimidazole (ß-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Bioorg Med Chem;
24(21): 5326-5339, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27614920
10.
Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.
Mol Pharm;
12(9): 3214-25, 2015 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26202880
11.
Functionalization of 68Ga-Radiolabeled Nanodiamonds with Octreotide Does Not Improve Tumor-Targeting Capabilities.
Pharmaceuticals (Basel);
17(4)2024 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38675474
12.
[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier.
J Cereb Blood Flow Metab;
44(1): 142-152, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37728771
13.
Tariquidar and elacridar are dose-dependently transported by P-glycoprotein and Bcrp at the blood-brain barrier: a small-animal positron emission tomography and in vitro study.
Drug Metab Dispos;
41(4): 754-62, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23305710
14.
Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats.
Eur J Pharm Sci;
183: 106404, 2023 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36773747
15.
Synthesis, radiolabeling, and preclinical in vivo evaluation of 68Ga-radiolabelled nanodiamonds.
Nucl Med Biol;
116-117: 108310, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36565646
16.
A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier.
J Neurosci;
31(24): 8803-11, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21677164
17.
A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.
Eur J Nucl Med Mol Imaging;
39(1): 149-59, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21983837
18.
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.
J Control Release;
342: 44-52, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34971693
19.
Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.
J Control Release;
349: 109-117, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35798092
20.
Radiosynthesis and in vivo evaluation of 1-[18F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein.
Bioorg Med Chem;
19(7): 2190-8, 2011 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21419632