Marginal bone response of submerged and non-submerged osteoconductive alkali-etched implants in thick and thin biotypes: A 2-year clinical follow-up study.

PURPOSE: This follow-up study evaluated the implant success rate and marginal bone response of submerged and non-submerged osteoconductive two-piece implants with a moderately rough implant neck in thick and thin gingival biotypes. MATERIALS AND METHODS: The stability of the hard tissue surrounding the implants was evaluated, based on clinical and radiographic examinations performed after implant placement and every follow-up thereafter. The clinical data were processed via linear mixed-effects model statistics at the patient level. RESULTS: Forty-three edentulous and partially edentulous patients were treated with a total of 97 implants with an osteoconductive surface. After 2 years in function, all the implants and dental prostheses reached a 100% success rate according to predefined criteria. Taking implantation as a baseline, the mean change in the marginal bone level (ΔMBLp) after 2 years in function was -0.36 mm (SD: 0.55), and bone resorption higher than 1 mm and less than 2.5 mm was observed for seven implants. Taking dental prosthesis placement as a baseline, the ΔMBLp after 2 years of loading was -0.13 mm (SD: 0.39), and bone resorption higher than 1 mm and less than 2.0 mm was observed only for two implants. Statistically significant differences in mean marginal bone loss were observed in the gingival biotype (P = .006) and submersion (P < .05). Their influence on the dynamics of peri-implant bone loss during the process of biologic width restoration was analyzed. CONCLUSION: This study demonstrated the high stability of peri-implant hard tissue and the 100% success rate of the implant system with a moderately rough neck. The biotype and implant submersion were evaluated as factors having a significant influence on marginal bone loss.

Secondary stability assessment of titanium implants with an alkali-etched surface: a resonance frequency analysis study in beagle dogs.

PURPOSE: This study was carried out to quantify the effect of an alkali-modified surface on implant stability during healing using an animal model. MATERIALS AND METHODS: A total of 24 screw-shaped, self-tapping, commercially pure titanium dental implants, divided into a test group (implants with an alkali-modified surface or "biosurface") and a control group (implants with a turned, machined surface) were inserted without pretapping in the tibiae of 3 beagle dogs. The resonance frequency analysis method was used to measure the implant stability quotient (ISQ) 0, 1, 3, 9, and 12 weeks after implantation. The animals were sacrificed after 2, 5, and 12 weeks, and the bone-implant contact (BIC%) was evaluated histomorphometrically. RESULTS: The difference in the osseointegration rates (deltaISQ/deltahealing time) between the implants with alkali-modified surface (biosurface) and those with a turned, machined surface was evaluated as a mean of 0.843 ISQ/week within the first 9 weeks of healing. The mean increase in the secondary implant stability was found to be proportional to the mean increase in the BIC at healing period earlier than 5 weeks. DISCUSSION: The characteristics that differed between the implant surfaces, ie, specific surface area, contact angle, and hydroxylation/hydration, may represent factors that influence the rate of osseointegration and the secondary implant stability. CONCLUSION: The alkali-treated surface enhances the secondary stability in the early stages of healing compared to the turned, machined surface, as a consequence of faster BIC formation.

18 months of experiences with the biotitanium replacement (Implaspin) used in treatment of degenerative lumbar spine diseases.

Between 2007-2008 forty two patients neurosurgery department of the KNTB (Regional Hospital of T. Bat'a) Zlin underwent surgery using the bioactive replacement Implaspin. The group of 21 patient of the total of number of 42 patients was operated first time for diagnosis degenerative instability or spondylolisthesis gr I-II. In this group was the follow-up period of 18 months, the mean baseline Oswestry score was 57%. A value of 37% was achieved after 18 months during the evaluation of the clinical status using the Oswestry questionnaire. This result represented a improvement of the condition. No change of the position of the instruments occurred during the X-ray and CT, MRI controls. Therefore, the Implaspin replacement appeared to be a perfect alternative to other lumbar spine replacements combining the osteoconductive properties of the bioactive material with the rigidity of titanium.

Bioactive titan cage Implaspin in treatment of degenerative disease of the cervcal spine--the results from 2007 till 2008.

The authors present results of surgical treatment of cervical spine degenerative disease via Implaspin biotitanium replacement. Surgery was indicated for a group of 24 patients with symptoms of cervical spondylogenic myelopathy or the irritation decay root syndrome non-reacting to conservative treatment. Pre-surgery X-ray and MRI examinations showed spinal canal stenosis caused by the intervertebral disk osteochondrosis combined with prolapse or dorsal osteophytes. Clinical problems of the group of patients were evaluated through the JOA classification before surgery and during the 2nd, the 6th and month 12th after surgery. The surgery rate of success was evaluated in percentages during post-surgery examinations that took place in the 12th month. Based on the JOA classification, that rate of success falls into the good surgery results zone. The post-surgery X-ray examinations showed two sank replacements by 1/3 of its height into the surrounding vertebral bodies. In these cases we performed the control MRI. No signs of the new spinal compression were found and the spinal canal was free in the operated site. Based on our short-term experiences, the Implaspin bioactive replacement seems to be a suitable alternative to the other types of replacements designed for intervertebral fusion in the lower cervical spine area.