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1.

NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Gu, Meidi; Zhou, Xiaofei; Sohn, Jee Hyung; Zhu, Lele; Jie, Zuliang; Yang, Jin-Young; Zheng, Xiaofeng; Xie, Xiaoping; Yang, Jie; Shi, Yaoyao; Brightbill, Hans D; Kim, Jae Bum; Wang, Jing; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 22(2): 193-204, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33398181

2.

Author Correction: The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.

Jin, Jin; Xiao, Yichuan; Chang, Jae-Hoon; Yu, Jiayi; Hu, Hongbo; Starr, Robyn; Brittain, George C; Chang, Mikyoung; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 21(9): 1134, 2020 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-32616919

3.

The deubiquitinase Otub1 controls the activation of CD8⁺ T cells and NK cells by regulating IL-15-mediated priming.

Zhou, Xiaofei; Yu, Jiayi; Cheng, Xuhong; Zhao, Baoyu; Manyam, Ganiraju C; Zhang, Li; Schluns, Kimberly; Li, Pingwei; Wang, Jing; Sun, Shao-Cong.

Nat Immunol; 20(7): 879-889, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31182807

4.

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis.

Jie, Zuliang; Yang, Jin-Young; Gu, Meidi; Wang, Hui; Xie, Xiaoping; Li, Yanchuan; Liu, Ting; Zhu, Lele; Shi, Jianhong; Zhang, Lingyun; Zhou, Xiaofei; Joo, Donghyun; Brightbill, Hans D; Cong, Yingzi; Lin, Daniel; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 19(11): 1224-1235, 2018 11.

Artículo en Inglés | MEDLINE | ID: mdl-30250187

5.

Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid.

Jin, Jin; Xie, Xiaoping; Xiao, Yichuan; Hu, Hongbo; Zou, Qiang; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 17(3): 259-68, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-26808229

6.

Author Correction: NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Gu, Meidi; Zhou, Xiaofei; Sohn, Jee Hyung; Zhu, Lele; Jie, Zuliang; Yang, Jin-Young; Zheng, Xiaofeng; Xie, Xiaoping; Yang, Jie; Shi, Yaoyao; Brightbill, Hans D; Kim, Jae Bum; Wang, Jing; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 22(4): 530, 2021 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-33574621

7.

A20 restricts inflammation via ubiquitin binding.

Sun, Shao-Cong.

Nat Immunol; 21(4): 362-364, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32205879

8.

USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses.

Zou, Qiang; Jin, Jin; Hu, Hongbo; Li, Haiyan S; Romano, Simona; Xiao, Yichuan; Nakaya, Mako; Zhou, Xiaofei; Cheng, Xuhong; Yang, Peirong; Lozano, Guillermina; Zhu, Chengming; Watowich, Stephanie S; Ullrich, Stephen E; Sun, Shao-Cong.

Nat Immunol; 15(6): 562-70, 2014 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-24777531

9.

The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses.

Ko, Chun-Jung; Zhang, Lingyun; Jie, Zuliang; Zhu, Lele; Zhou, Xiaofei; Xie, Xiaoping; Gao, Tianxiao; Yang, Jin-Young; Cheng, Xuhong; Sun, Shao-Cong.

EMBO J; 40(2): e104532, 2021 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-33215753

10.

Myeloid cell TBK1 restricts inflammatory responses.

Gao, Tianxiao; Liu, Ting; Ko, Chun-Jung; Zhang, Lingyun; Joo, Donghyun; Xie, Xiaoping; Zhu, Lele; Li, Yanchuan; Cheng, Xuhong; Sun, Shao-Cong.

Proc Natl Acad Sci U S A; 119(4)2022 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-35074921

11.

The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.

Jin, Jin; Xiao, Yichuan; Chang, Jae-Hoon; Yu, Jiayi; Hu, Hongbo; Starr, Robyn; Brittain, George C; Chang, Mikyoung; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 13(11): 1101-9, 2012 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-23023393

12.

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells.

Chang, Jae-Hoon; Xiao, Yichuan; Hu, Hongbo; Jin, Jin; Yu, Jiayi; Zhou, Xiaofei; Wu, Xuefeng; Johnson, Howard M; Akira, Shizuo; Pasparakis, Manolis; Cheng, Xuhong; Sun, Shao-Cong.

Nat Immunol; 13(5): 481-90, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22484734

13.

FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.

Meng, Xiangbo; Liu, Xiwei; Guo, Xingdong; Jiang, Shutan; Chen, Tingting; Hu, Zhiqiang; Liu, Haifeng; Bai, Yibing; Xue, Manman; Hu, Ronggui; Sun, Shao-Cong; Liu, Xiaolong; Zhou, Penghui; Huang, Xiaowu; Wei, Lai; Yang, Wei; Xu, Chenqi.

Nature; 564(7734): 130-135, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30487606

14.

Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death.

Ang, Rosalind L; Chan, Mark; Legarda, Diana; Sundberg, John P; Sun, Shao-Cong; Gillespie, Virginia L; Chun, Nicholas; Heeger, Peter S; Xiong, Huabao; Lira, Sergio A; Ting, Adrian T.

Proc Natl Acad Sci U S A; 118(50)2021 12 14.

Artículo en Inglés | MEDLINE | ID: mdl-34887354

15.

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.

Chang, Mikyoung; Jin, Wei; Chang, Jae-Hoon; Xiao, Yichuan; Brittain, George C; Yu, Jiayi; Zhou, Xiaofei; Wang, Yi-Hong; Cheng, Xuhong; Li, Pingwei; Rabinovich, Brian A; Hwu, Patrick; Sun, Shao-Cong.

Nat Immunol; 12(10): 1002-9, 2011 Aug 28.

Artículo en Inglés | MEDLINE | ID: mdl-21874024

16.

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.

Li, Yanchuan; Xie, Xiaoping; Jie, Zuliang; Zhu, Lele; Yang, Jin-Young; Ko, Chun-Jung; Gao, Tianxiao; Jain, Antrix; Jung, Sung Yun; Baran, Natalia; Konopleva, Marina Y; Cheng, Xuhong; Sun, Shao-Cong.

Blood; 138(23): 2360-2371, 2021 12 09.

Artículo en Inglés | MEDLINE | ID: mdl-34255829

17.

Cylindromatosis drives synapse pruning and weakening by promoting macroautophagy through Akt-mTOR signaling.

Zajicek, Alexis S; Ruan, Hongyu; Dai, Huihui; Skolfield, Mary C; Phillips, Hannah L; Burnette, Wendi J; Javidfar, Behnam; Sun, Shao-Cong; Akbarian, Schahram; Yao, Wei-Dong.

Mol Psychiatry; 27(5): 2414-2424, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35449295

18.

Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.

Nakaya, Mako; Xiao, Yichuan; Zhou, Xiaofei; Chang, Jae-Hoon; Chang, Mikyoung; Cheng, Xuhong; Blonska, Marzenna; Lin, Xin; Sun, Shao-Cong.

Immunity; 40(5): 692-705, 2014 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-24792914

19.

Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity.

Jin, Jin; Hu, Hongbo; Li, Haiyan S; Yu, Jiayi; Xiao, Yichuan; Brittain, George C; Zou, Qiang; Cheng, Xuhong; Mallette, Frédérick A; Watowich, Stephanie S; Sun, Shao-Cong.

Immunity; 40(3): 342-54, 2014 Mar 20.

Artículo en Inglés | MEDLINE | ID: mdl-24656046

20.

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang, Bin; Jie, Zuliang; Joo, Donghyun; Ordureau, Alban; Liu, Pengda; Gan, Wenjian; Guo, Jianping; Zhang, Jinfang; North, Brian J; Dai, Xiangpeng; Cheng, Xuhong; Bian, Xiuwu; Zhang, Lingqiang; Harper, J Wade; Sun, Shao-Cong; Wei, Wenyi.

Nature; 545(7654): 365-369, 2017 05 18.

Artículo en Inglés | MEDLINE | ID: mdl-28489822

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