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1.
TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice.
Cell Mol Life Sci;
80(5): 133, 2023 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37185787
2.
Evaluation of Some Safety Parameters of Dual Histamine H3 and Sigma-2 Receptor Ligands with Anti-Obesity Potential.
Int J Mol Sci;
24(8)2023 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37108661
3.
In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione.
Toxicol Appl Pharmacol;
457: 116318, 2022 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36414119
4.
Preliminary Evidence of the Potent and Selective Adenosine A2B Receptor Antagonist PSB-603 in Reducing Obesity and Some of Its Associated Metabolic Disorders in Mice.
Int J Mol Sci;
23(21)2022 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36362227
5.
KSK-74: Dual Histamine H3 and Sigma-2 Receptor Ligand with Anti-Obesity Potential.
Int J Mol Sci;
23(13)2022 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35806019
6.
Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides.
Int J Mol Sci;
22(23)2021 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34884898
7.
The Slow-Releasing and Mitochondria-Targeted Hydrogen Sulfide (H2S) Delivery Molecule AP39 Induces Brain Tolerance to Ischemia.
Int J Mol Sci;
22(15)2021 Jul 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34360581
8.
Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands.
Bioorg Chem;
91: 103071, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31362197
9.
Beneficial effects of non-quinazoline α1-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin.
Nutr Metab Cardiovasc Dis;
29(7): 751-760, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31133498
10.
QUANTIFICATION AND PHARMACOKINETICS OF 1 -METHYLPYRIDINIUM AND 1,4-DIMETHYLPYRIDINIUM IN RATS BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY. TISSUE DISTRIBUTION OF 1,4-DIMETHYLPYRIDINIUM IN RATS.
Acta Pol Pharm;
73(5): 1111-1121, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29638051
11.
Pharmacokinetics and tissue distribution of the new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy) propyl]piperidine in rats.
Xenobiotica;
45(10): 912-20, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25869247
12.
Novel Alaninamide Derivatives with Drug-like Potential for Development as Antiseizure and Antinociceptive TherapiesâIn Vitro and In Vivo Characterization.
ACS Chem Neurosci;
15(11): 2198-2222, 2024 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38741575
13.
Liquid chromatography-mass spectrometry method for the analysis of 1,4-dimethylpyridinium in rat plasma--application to pharmacokinetic studies.
Biomed Chromatogr;
27(1): 73-9, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22549824
14.
Manifestations of Liver Impairment and the Effects of MH-76, a Non-Quinazoline α1-Adrenoceptor Antagonist, and Prazosin on Liver Tissue in Fructose-Induced Metabolic Syndrome.
Metabolites;
13(11)2023 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37999226
15.
Capillary electrophoresis/frontal analysis versus equilibrium dialysis in dexamethasone sodium phosphate-serum albumin binding studies.
Electrophoresis;
33(22): 3323-30, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23097126
16.
Binding of 1-[3-(4-tert-butyl-phenoxy)propyl]piperidine, a new non imidazole histamine H3 receptor antagonist to bovine serum albumin.
Acta Pol Pharm;
69(6): 1043-7, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23285664
17.
Guanabenz-an old drug with a potential to decrease obesity.
Naunyn Schmiedebergs Arch Pharmacol;
395(8): 963-974, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35511242
18.
Combined hyperforin and lanicemine treatment instead of ketamine or imipramine restores behavioral deficits induced by chronic restraint stress and dietary zinc restriction in mice.
Front Pharmacol;
13: 933364, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36091748
19.
Discovery of (R)-N-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [(R)-AS-1], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity In Vivo.
J Med Chem;
65(17): 11703-11725, 2022 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35984707
20.
LC-MS-MS Method for the Analysis of New Non-Imidazole Histamine H(3) Receptor Antagonist 1-[3-(4-tert-Butylphenoxy)propyl]piperidine in Rat Serum-Application to Pharmacokinetic Studies.
Chromatographia;
73(9-10): 913-919, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21544189