Detalles de la búsqueda
1.
4-Methylumbelliferone-Functionalized Polyphosphazene and Its Assembly into Biocompatible Fluorinated Nanocoatings with Selective Antiproliferative Activity.
Biomacromolecules;
24(5): 2278-2290, 2023 05 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37071718
2.
Fluorine-Functionalized Polyphosphazene Immunoadjuvant: Synthesis, Solution Behavior and In Vivo Potency.
Molecules;
28(10)2023 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37241958
3.
Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.
PLoS Biol;
16(1): e2004111, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29357353
4.
Cooperative assembly of a four-molecule signaling complex formed upon T cell antigen receptor activation.
Proc Natl Acad Sci U S A;
115(51): E11914-E11923, 2018 12 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30510001
5.
Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome.
Proc Natl Acad Sci U S A;
115(9): 2174-2179, 2018 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29440413
6.
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
J Biol Chem;
294(46): 17654-17668, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31481464
7.
A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
J Biol Chem;
293(21): 7993-8008, 2018 05 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29602904
8.
Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex.
Biochemistry;
54(11): 2001-10, 2015 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-25753752
9.
Binding of a third metal ion by the human phosphatases PP2Cα and Wip1 is required for phosphatase activity.
Biochemistry;
52(34): 5830-43, 2013 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-23906386
10.
Monitoring Protein Complexation with Polyphosphazene Polyelectrolyte Using Automated Dynamic Light Scattering Titration and Asymmetric Flow Field Flow Fractionation and Protein Recognition Immunoassay.
ACS Polym Au;
3(5): 354-364, 2023 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37841951
11.
Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design.
Bioorg Med Chem Lett;
22(2): 1130-5, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22178553
12.
Alkyl-substituted N-methylaryl-N'-aryl-4-aminobenzamides: A new series of small molecule inhibitors for Wip1 phosphatase.
Eur J Med Chem;
243: 114763, 2022 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36179402
13.
Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen.
ACS Pharmacol Transl Sci;
5(10): 993-1006, 2022 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36268125
14.
Structure-guided design and synthesis of P1' position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors.
Bioorg Med Chem;
19(17): 5238-46, 2011 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21803585
15.
Design of pentapeptidic BACE1 inhibitors with carboxylic acid bioisosteres at P1' and P4 positions.
Bioorg Med Chem;
18(9): 3175-86, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20381362
16.
Tetrapeptides, as small-sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1.
J Pept Sci;
16(6): 257-62, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20474036
17.
Chemical Features Important for Activity in a Class of Inhibitors Targeting the Wip1 Flap Subdomain.
ChemMedChem;
13(9): 894-901, 2018 05 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29476592
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