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1.
Molecular Complexity as a Driver for Chemical Process Innovation in the Pharmaceutical Industry.
J Org Chem;
84(8): 4583-4603, 2019 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30916557
2.
Isolation and structure elucidation of unexpected in-process impurities during tetrazole ring formation of an investigational drug substance.
Magn Reson Chem;
55(4): 253-262, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26841697
3.
Direct reductive amination of aldehyde bisulfite adducts induced by 2-picoline borane: application to the synthesis of a DPP-IV inhibitor.
J Org Chem;
78(4): 1655-9, 2013 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23308360
4.
Atroposelective Brønsted Acid-Catalyzed Photocyclization to Access Chiral N-Aryl Quinolones with Low Rotational Barriers.
Org Lett;
25(31): 5856-5861, 2023 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37499637
5.
Separation and quantitation of eight isomers in a molecule with three stereogenic centers by normal phase liquid chromatography.
J Chromatogr A;
1538: 108-111, 2018 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29397985
6.
Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J Med Chem;
49(13): 3832-49, 2006 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-16789740
7.
Highly Regioselective Halogenation of Pyridine N-Oxide: Practical Access to 2-Halo-Substituted Pyridines.
Org Lett;
17(12): 2948-51, 2015 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-26037223
8.
Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.
ACS Med Chem Lett;
6(9): 987-92, 2015 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26396685
9.
Magnesium halide-catalyzed anti-aldol reactions of chiral N-acylthiazolidinethiones.
Org Lett;
4(7): 1127-30, 2002 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-11922799
10.
Enantioselective Syntheses of 2-Deoxyxylono-1,4-lactone and 2-Deoxyribono-1,4-lactone from 1,3-Dioxan-5-yl Diazoacetates.
J Org Chem;
64(24): 8907-8915, 1999 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-11674797
11.
An efficient, regioselective amination of 3,5-disubstituted pyridine N-oxides using saccharin as an ammonium surrogate.
Org Lett;
15(1): 168-71, 2013 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23234245
12.
Chiral Mixed Phosphorus/Sulfur Ligands for Palladium-Catalyzed Allylic Alkylations and Aminations.
J Org Chem;
64(9): 2994-2995, 1999 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-11674390
13.
Chiral Salen-Aluminum Complexes as Catalysts for Enantioselective Aldol Reactions of Aldehydes and 5-Alkoxyoxazoles: An Efficient Approach to the Asymmetric Synthesis of syn and anti beta-Hydroxy-alpha-amino Acid Derivatives Financial support has been provided by the National Institutes of Health (GM 43912-11 and GM 33328-18).
Angew Chem Int Ed Engl;
40(10): 1884-1888, 2001 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-11385662
14.
Highly selective rhodium-catalyzed conjugate addition reactions of 4-oxobutenamides.
J Org Chem;
72(23): 8870-6, 2007 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-17927253
15.
Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids.
Bioorg Med Chem Lett;
17(10): 2817-22, 2007 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17350258
16.
Stereoselective synthesis of a MCHr1 antagonist.
J Org Chem;
72(25): 9648-55, 2007 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-17997573
17.
Reversal of diastereofacial selectivity in hydride reductions of N-tert-butanesulfinyl imines.
J Org Chem;
71(18): 6859-62, 2006 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16930038
18.
Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties.
Bioorg Med Chem Lett;
16(13): 3574-7, 2006 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16632353
19.
Application of chiral mixed phosphorus/sulfur ligands to enantioselective rhodium-catalyzed dehydroamino acid hydrogenation and ketone hydrosilylation processes.
J Am Chem Soc;
125(12): 3534-43, 2003 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-12643715
20.
Diastereoselective magnesium halide-catalyzed anti-aldol reactions of chiral N-acyloxazolidinones.
J Am Chem Soc;
124(3): 392-3, 2002 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-11792206
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