Hydrodynamic Mechanism for Clumping along the Equatorial Rings of SN1987A and Other Stars.

An explanation for the origin and number of clumps along the equatorial ring of Supernova 1987A has eluded decades of research. Our linear analysis and hydrodynamic simulations of the expanding ring prior to the supernova reveal that it is subject to the Crow instability between vortex cores. The dominant wave number is remarkably consistent with the number of clumps, suggesting that the Crow instability stimulates clump formation. Although the present analysis focuses on linear fluid flow, future nonlinear analysis and the incorporation of additional stellar physics may further elucidate the remnant structure and the evolution of the progenitor and other stars.

In vitro activity of cysteamine against SARS-CoV-2 variants.

Global COVID-19 pandemic is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Continuous emergence of new variants and their rapid spread are jeopardizing vaccine countermeasures to a significant extent. While currently available vaccines are effective at preventing illness associated with SARS-CoV-2 infection, these have been shown to be less effective at preventing breakthrough infection and transmission from a vaccinated individual to others. Here we demonstrate broad antiviral activity of cysteamine HCl in vitro against major emergent infectious variants of SARS-CoV-2 in a highly permissible Vero cell line. Cysteamine HCl inhibited infection of wild type, alpha, beta, gamma, delta, lambda, and omicron variants effectively. Cysteamine is a very well-tolerated US FDA-approved drug used chronically as a topical ophthalmic solution to treat ocular cystinosis in patients who receive it hourly or QID lifelong at concentrations 6 times higher than that required to inhibit SARS CoV-2 in tissue culture. Application of cysteamine as a topical nasal treatment can potentially1) mitigate existing infection 2) prevent infection in exposed individuals, and 3) limit the contagion in vulnerable populations.

An azimuthal Fourier domain formulation of the Ffowcs Williams and Hawkings equation.

The acoustic field of high-speed turbulent jets is dominated by a small number of low-wavenumber azimuthal Fourier modes. Accordingly, it is of interest to directly obtain individual azimuthal modes of the acoustic field from simulation data or models of the jet near-field. To this end, we manipulate the Ffowcs Williams and Hawkings (FW-H) equation to obtain a new formulation that lives entirely in the azimuthal Fourier domain-it delivers individual azimuthal modes of the acoustic field as a function of the same azimuthal modes of the near-field FW-H source term or, upon linearization of the source terms, as a function of the same azimuthal modes of the near-field flow variables. As an added benefit, all surface integrals are converted into line integrals in the streamwise-radial plane. After verifying and validating our formulation using a monopole problem with an exact solution and large-eddy simulation data, respectively, we show how our method can be used to efficiently and naturally compute the acoustic field associated with resolvent modes of a Mach 1.5 jet, thus avoiding the need to compute the modes on a large computational domain to capture their acoustic radiation.

Resolvent-based modeling of turbulent jet noise.

Resolvent analysis has demonstrated encouraging results for modeling coherent structures in jets when compared against their data-educed counterparts from high-fidelity large-eddy simulations (LES). We formulate resolvent analysis as an acoustic analogy that relates the near-field resolvent forcing to the near- and far-field pressure. We use an LES database of round, isothermal, Mach 0.9 and 1.5 jets to produce an ensemble of realizations for the acoustic field that we project onto a limited set of resolvent modes. In the near-field, we perform projections on a restricted acoustic output domain, r/D=[5,6], while the far-field projections are performed on a Kirchhoff surface comprising a 100-diameter arc centered at the nozzle. This allows the LES realizations to be expressed in the resolvent basis via a data-deduced, low-rank, cross-spectral density matrix. We find that a single resolvent mode reconstructs the most energetic regions of the acoustic field across Strouhal numbers, St=[0-1], and azimuthal wavenumbers, m=[0,2]. Finally, we present a simple function that results in a rank-1 resolvent model agreeing within 2 dB of the peak noise for both jets.

Space-time POD and the Hankel matrix.

Time-delay embedding is an increasingly popular starting point for data-driven reduced-order modeling efforts. In particular, the singular value decomposition (SVD) of a block Hankel matrix formed from successive delay embeddings of the state of a dynamical system lies at the heart of several popular reduced-order modeling methods. In this paper, we show that the left singular vectors of this Hankel matrix are a discrete approximation of space-time proper orthogonal decomposition (POD) modes, and the singular values are square roots of the POD energies. Analogous to the connection between the SVD of a data matrix of snapshots and space-only POD, this connection establishes a clear interpretation of the Hankel modes grounded in classical theory, and we gain insights into the Hankel modes by instead analyzing the equivalent discrete space-time POD modes in terms of the correlation matrix formed by multiplying the Hankel matrix by its conjugate transpose. These insights include the distinct meaning of rows and columns, the implied norm in which the modes are optimal, the impact of the time step between snapshots on the modes, and an interpretation of the embedding dimension/height of the Hankel matrix in terms of the time window on which the modes are optimal. Moreover, the connections we establish offer opportunities to improve the convergence and computation time in certain practical cases, and to improve the accuracy of the modes with the same data. Finally, popular variants of POD, namely the standard space-only POD and spectral POD, are recovered in the limits that snapshots used to form each column of the Hankel matrix represent flow evolution over short and long times, respectively.