Two-year outcomes from the Australian and New Zealand Emergency Laparotomy Audit-Quality Improvement pilot study.

BACKGROUND: The aim of the Australian and New Zealand Emergency Laparotomy Audit-Quality Improvement (ANZELA-QI) pilot study was to determine (i) the outcomes of emergency laparotomy (EL) and (ii) the feasibility of a national, multi-disciplinary quality improvement (QI) project based on a bundle of evidence-based care standards. METHODS: An online database was created using the Research Electronic Data Capture (REDCap) programme. National ethics approval with waiver of consent was obtained. Data were entered directly onto REDCap and extracted monthly for eight care standards (preoperative consultant radiologist reporting of computed tomography scans, preoperative mortality risk score, consultant presence in theatre, timely access to theatre and critical care commensurate with risk and involvement of aged care). Monthly QI run charts using 'traffic' light graphics (green ≥80%, amber ≥50% to <80% and red <50%) reported compliance with the standards. RESULTS: Sixty hospitals indicated interest, but difficulties with site-specific ethics approval resulted in only 24 hospitals participating (2886 EL in 2755 patients). The overall in-hospital mortality was 7.1% (2.3%-13.3%) and average length of stay 15.5 (8.6-22.7) days. Both significantly declined. Preoperative risk assessment (overall 45%) improved almost three-fold during the study. Only 60% had timely access to theatre and only 70% with a predicted mortality risk of >10% were admitted to critical care. CONCLUSION: Overall mortality compared favourably with similar international studies and declined in association with participation in the audit. Compliance with some care standards shows considerable scope to improve EL care using QI methodology.

Confidence limits of arteriovenous fistula flow rate measured by the "on-line" thermodilution technique.

BACKGROUND: A method is presented for estimating the confidence limits (CLs), or accuracy, of the arteriovenous fistula flow rate measured at haemodialysis by the "on-line" thermodilution technique. METHODS: This was by derivation of an expression to estimate what variance a set of repeated measures of flow would yield, using values pertaining to a single measure of flow. (Laws of variance were applied to the formula used to calculate flow, to account for its variables' values and measurement errors.) This enabled CLs of a single measure to be estimated. RESULTS: The variance estimated from a single measure was compared with that actually observed upon immediately taking a second measurement; differences in 189 pairs were not significantly different from zero (P=0.56). Applying the results demonstrated that measured flow values of 430-570 ml/min typically had associated 95% CLs that included 500 ml/min; therefore, true flow could not be said to be either side of 500 ml/min. The same was the case for 500-700 ml/min with regard to 600 ml/min. CLs widened considerably with the magnitude of flow rate, limiting the accurate measurement of higher flows and the detection of falls in flow. CONCLUSION: A method to estimate CLs of flow rate measured by the thermodilution technique is presented and validated. Application demonstrates an accurate measurement of low flow, but limitations at higher flow and in detecting falls in flow. Appreciating the magnitude of such is critical to informed clinical decision making when using flow rate in an access surveillance programme.