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1.
The use of recovery animals in nonclinical safety assessment studies with monoclonal antibodies: further 3Rs opportunities remain.
Regul Toxicol Pharmacol;
138: 105339, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36649820
2.
Re-evaluating the need for chronic toxicity studies with therapeutic monoclonal antibodies, using a weight of evidence approach.
Regul Toxicol Pharmacol;
138: 105329, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36592682
3.
An IQ Consortium Perspective on The Scientific Committee on Health, Environmental and Emerging Risks Final Opinion on the Need for Nonhuman Primates in Biomedical Research, Production and Testing of Products and Devices (Update 2017).
Toxicol Pathol;
47(5): 649-655, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31280699
4.
In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity.
Int J Toxicol;
36(1): 35-49, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28056568
5.
Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti-programmed cell death protein-1 (PD-1) antibody, in human cancer models.
Cancer Chemother Pharmacol;
89(4): 515-527, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35298699
6.
Challenges and solutions in the bioanalysis of BMS-986094 and its metabolites including a highly polar, active nucleoside triphosphate in plasma and tissues using LC-MS/MS.
J Chromatogr B Analyt Technol Biomed Life Sci;
1000: 29-40, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26209768
7.
Development and validation of a liquid chromatography tandem mass spectrometry assay for the quantitation of a protein therapeutic in cynomolgus monkey serum.
J Chromatogr B Analyt Technol Biomed Life Sci;
988: 81-7, 2015 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25756208
8.
Oxidative stress and its role in skin disease.
Antioxid Redox Signal;
4(4): 665-73, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12230879
9.
Sodium arsenite-induced stress-related gene expression in normal human epidermal, HaCaT, and HEL30 keratinocytes.
Environ Health Perspect;
110 Suppl 5: 761-6, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12426128
10.
Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-Ha-ras transgenic (Tg.AC) mice.
Environ Health Perspect;
112(12): 1255-63, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15345372
11.
Coordination of altered DNA repair and damage pathways in arsenite-exposed keratinocytes.
Toxicol Sci;
69(2): 306-16, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12377979
12.
Improved liquid-liquid extraction with inter-well volume replacement dilution workflow and its application to quantify BMS-927711 in rat dried blood spots by UHPLC-MS/MS.
J Pharm Biomed Anal;
89: 240-50, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24316424
13.
A rapid, accurate and robust UHPLC-MS/MS method for quantitative determination of BMS-927711, a CGRP receptor antagonist, in plasma in support of non-clinical toxicokinetic studies.
J Pharm Biomed Anal;
83: 237-48, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23770636
14.
Comprehensive investigation of hydroxypropyl methylcellulose, propylene glycol, polysorbate 80, and hydroxypropyl-beta-cyclodextrin for use in general toxicology studies.
Toxicol Sci;
117(2): 485-92, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20643750
15.
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Toxicol In Vitro;
24(1): 1-9, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19490935
16.
Arsenic-induced alterations in the contact hypersensitivity response in Balb/c mice.
Toxicol Appl Pharmacol;
198(3): 434-43, 2004 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15276424
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