Detalles de la búsqueda
1.
Characterization of adductomic totality of NNK, (R)-NNAL and (S)-NNAL in A/J mice, and their correlations with distinct lung carcinogenicity.
Carcinogenesis;
43(2): 170-181, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34919675
2.
Investigation of 2'-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N'-Nitrosonornicotine Metabolism.
Chem Res Toxicol;
34(4): 1004-1015, 2021 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33720703
3.
Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4-Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung.
Chem Res Toxicol;
34(3): 723-732, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33629582
4.
Modulation of the PD-1/PD-L1 immune checkpoint axis during inflammation-associated lung tumorigenesis.
Carcinogenesis;
41(11): 1518-1528, 2020 11 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32602900
5.
Mass Spectrometric Quantitation of Apurinic/Apyrimidinic Sites in Tissue DNA of Rats Exposed to Tobacco-Specific Nitrosamines and in Lung and Leukocyte DNA of Cigarette Smokers and Nonsmokers.
Chem Res Toxicol;
33(9): 2475-2486, 2020 09 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32833447
6.
Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice.
Chem Res Toxicol;
33(7): 1980-1988, 2020 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32476407
7.
Hyaluronan-CD44/RHAMM interaction-dependent cell proliferation and survival in lung cancer cells.
Mol Carcinog;
58(3): 321-333, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30365189
8.
Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.
Chem Res Toxicol;
32(4): 773-783, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30740971
9.
Strain-specific altered nicotine metabolism in 3,3'-diindolylmethane (DIM) exposed mice.
Biopharm Drug Dispos;
40(5-6): 188-194, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-31016737
10.
Nitric oxide-donating aspirin (NO-Aspirin) suppresses lung tumorigenesis in vitro and in vivo and these effects are associated with modulation of the EGFR signaling pathway.
Carcinogenesis;
39(7): 911-920, 2018 07 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29982425
11.
Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Carcinogenesis;
39(2): 232-241, 2018 02 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29194532
12.
In Vivo Stable-Isotope Labeling and Mass-Spectrometry-Based Metabolic Profiling of a Potent Tobacco-Specific Carcinogen in Rats.
Anal Chem;
90(20): 11863-11872, 2018 10 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-30086646
13.
Analysis and Identification of 2'-Deoxyadenosine-Derived Adducts in Lung and Liver DNA of F-344 Rats Treated with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Chem Res Toxicol;
31(5): 358-370, 2018 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29651838
14.
Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Chem Res Toxicol;
31(1): 48-57, 2018 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29131934
15.
Multiclass Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry.
Anal Chem;
88(9): 4780-7, 2016 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27043225
16.
Transcriptome profiling in oral cavity and esophagus tissues from (S)-N'-nitrosonornicotine-treated rats reveals candidate genes involved in human oral cavity and esophageal carcinogenesis.
Mol Carcinog;
55(12): 2168-2182, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-26785143
17.
Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification.
Drug Metab Dispos;
44(3): 422-7, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26744252
18.
DNA Adduct Formation from Metabolic 5'-Hydroxylation of the Tobacco-Specific Carcinogen N'-Nitrosonornicotine in Human Enzyme Systems and in Rats.
Chem Res Toxicol;
29(3): 380-9, 2016 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26808005
19.
Analysis of O(6)-[4-(3-Pyridyl)-4-oxobut-1-yl]-2'-deoxyguanosine and Other DNA Adducts in Rats Treated with Enantiomeric or Racemic N'-Nitrosonornicotine.
Chem Res Toxicol;
29(1): 87-95, 2016 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-26633576
20.
Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines.
Chem Res Toxicol;
29(12): 2194-2205, 2016 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27989137