Detalles de la búsqueda
1.
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity.
J Chem Inf Model;
63(21): 6900-6911, 2023 11 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37910792
2.
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Molecules;
28(13)2023 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-37446625
3.
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction.
J Chem Inf Model;
54(10): 2621-6, 2014 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-25289483
4.
Analysis of illicit dietary supplements sold in the Italian market: identification of a sildenafil thioderivative as adulterant using UPLC-TOF/MS and GC/MS.
Sci Justice;
54(3): 228-37, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24796952
5.
Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
Prog Neuropsychopharmacol Biol Psychiatry;
131: 110963, 2024 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38354897
6.
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines.
Biochem Pharmacol;
: 116161, 2024 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38522556
7.
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models.
Sci Rep;
14(1): 6491, 2024 03 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38499619
8.
Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors.
Bioorg Med Chem Lett;
23(19): 5290-4, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23988354
9.
Enhancement of peripheral fatty acyl ethanolamide signaling prevents stress-induced social avoidance and anxiety-like behaviors in male rats.
Psychopharmacology (Berl);
2023 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37932554
10.
Combined targeting of fatty acid amide hydrolase and melatonin receptors promotes neuroprotection and stimulates inflammation resolution in rats.
Br J Pharmacol;
180(10): 1316-1338, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36526591
11.
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization.
Eur J Med Chem;
245(Pt 2): 114916, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36399878
12.
Disentangling the interactions between nasopharyngeal and gut microbiome and their involvement in the modulation of COVID-19 infection.
Microbiol Spectr;
: e0219423, 2023 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37728335
13.
Brain pharmacokinetics of non-imidazole biphenyl H3 receptor antagonists: a liquid chromatography/electrospray-mass spectrometry and ex vivo binding study in rats.
Chem Biodivers;
9(7): 1231-9, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22782872
14.
Liquid chromatography-mass spectrometric method for determination of the non-imidazole H3-receptor antagonist UPR1056 in rat plasma.
J Sep Sci;
34(14): 1656-63, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21648077
15.
Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph-Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice.
Pharmaceuticals (Basel);
15(1)2021 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35056098
16.
[18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma.
Front Oncol;
11: 760732, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34712616
17.
N-(Anilinoethyl)amide Melatonergic Ligands with Improved Water Solubility and Metabolic Stability.
ChemMedChem;
16(19): 3071-3082, 2021 10 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34213063
18.
A sulfonyl fluoride derivative inhibits EGFRL858R/T790M/C797S by covalent modification of the catalytic lysine.
Eur J Med Chem;
225: 113786, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34464874
19.
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend.
ChemSusChem;
14(12): 2591-2600, 2021 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33905170
20.
Qualitative structure-metabolism relationships in the hydrolysis of carbamates.
Drug Metab Rev;
42(4): 551-89, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20441444