Combined massive allograft and intramedullary vascularized fibula transfer: the Capanna technique for treatment of congenital pseudarthrosis of the tibia.

Background and purpose - Congenital pseudarthrosis of the tibia (CPT) is caused by local periosteal disease that can lead to bowing, fracturing, and pseudarthrosis. Current most successful treatment methods are segmental bone transport and vascularized and non-vascularized bone grafting. These methods are commonly hampered by discomfort, reoperations, and long-term complications. We report a combination of a vascularized fibula graft and large bone segment allograft, to improve patient comfort with similar outcomes.Patients and methods - 7 limbs that were operated on in 6 patients between November 2007 and July 2018 with resection of the CPT and reconstruction with a vascularized fibula graft in combination with a bone allograft were retrospectively studied. The mean follow-up time was 5.4 years (0.9-9.6). Postoperative endpoints: time to discharge, time to unrestricted weight bearing, complications within 30 days, consolidation, number of fractures, and secondary deformities.Results - The average time to unrestricted weight bearing with removable orthosis was 3.5 months (1.2-7.8). All proximal anastomoses consolidated within 10 months (2-10). 4 of the 7 grafts fractured at the distal anastomosis between 6 and 14 months postoperatively. After reoperation, consolidation of the distal anastomosis was seen after 2.8 months (2-4). 1 patient required a below-knee amputation.Interpretation - This case series showed favorable results of the treatment of CPT through a combination of a vascularized fibula graft and large bone segment allograft, avoiding the higher reintervention rate and discomfort with ring frame bone transport, and the prolonged non-weight bearing with vascularized fibula transfer without reinforcement with a massive large bone segment allograft.

Combined Massive Allograft and Intramedullary Vascularized Fibula as the Primary Reconstruction Method for Segmental Bone Loss in the Lower Extremity: A Systematic Review and Meta-Analysis.

BACKGROUND: Reconstruction of segmental bone loss due to malignancy, infection, or trauma is a challenge for the reconstructive surgeon. The combination of a vascularized fibular flap with a cortical allograft provides a reliable reconstructive option in the lower extremity. In this systematic review, we describe the outcome of this technique for the treatment of segmental bone loss. METHODS: A systematic review was performed on the use of a combined massive allograft and intramedullary vascularized fibula as a reconstruction method for large bone defects. We used PubMed, Embase, and the Wiley Cochrane Library. RESULTS: Seventeen clinical articles were included between 1997 and 2017, reporting 329 cases of lower-extremity reconstructions. A meta-analysis was performed on primary union rates. The main outcome measures were primary union rate, complication rate, reintervention rate, and function after reconstruction. All publications showed relatively high complication (5.9% to 85.7%) and reintervention rates (10% to 91.7%) with good primary union rates (66.7% to 100%) and functional outcome (range of mean Musculoskeletal Tumor Society [MSTS] scores, 24 to 29 points). CONCLUSIONS: The combination of a massive allograft with intramedullary vascularized fibula provides a single-step reconstruction method for large bone defects (>6 cm) in the lower extremity, with good long-term outcomes. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

The effect of flexor hallucis longus harvest on hallux function: a retrospective cross-sectional cohort study.

BACKGROUND AND AIM: Our aim was to evaluate the long-term morbidity of the hallux function after harvesting a free fibula flap. Special attention was given to the differences between patients who underwent the dissection of an osteo-cutaneous flap (without inclusion of the flexor hallucis longus (FHL) muscle) and patients who were treated with an osteo-myo-cutaneous (with inclusion of the FHL muscle). METHODS: During the period 1995-2009, 167 patients underwent an autologous mandible reconstruction using a free fibula flap. By the time of our investigation, 64 patients were deceased, 29 patients were lost to follow-up, 14 patients did not meet the inclusion criteria and 28 patients were unable or unwilling to come to the hospital. Thus, 32 patients were examined in this study. Combined flexion strength of the hallux flexors and range of motion (ROM) of the metatarsophalangeal (MTP) and interphalangeal (IP) joints were measured. RESULTS: Hallux flexion strength tests showed a significant decrease in strength in the operated leg versus control, 28±16.6 versus 37±19.2 N/s (p=0.003). The ROM for the MTP was significantly lower for the donor leg than for the control leg: 26±12° versus 30±10° (p=0.024) for plantar flexion and 30±13° versus 37±11° (p<0.001) for dorsal flexion. In addition, the ROM for plantar flexion in the IP joint was significantly lower in the donor group. No significant differences were found when comparing reduction of flexion strength or reduction of ROM in the osteo-cutaneous versus osteo-myo-cutaneous harvest. CONCLUSIONS: The main conclusion to be drawn from our results is that free fibula flap donor site morbidity in terms of hallux function is independent of the inclusion or exclusion of the FHL muscle in the flap. LEVEL OF EVIDENCE III: Retrospective cohort or comparative study; case-control study; or systematic review of these studies.