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1.

Mechanism of Substrate Translocation in an Alternating Access Transporter.

Latorraca, Naomi R; Fastman, Nathan M; Venkatakrishnan, A J; Frommer, Wolf B; Dror, Ron O; Feng, Liang.

Cell; 169(1): 96-107.e12, 2017 03 23.

Artículo en Inglés | MEDLINE | ID: mdl-28340354

2.

Crystal Structure of an LSD-Bound Human Serotonin Receptor.

Wacker, Daniel; Wang, Sheng; McCorvy, John D; Betz, Robin M; Venkatakrishnan, A J; Levit, Anat; Lansu, Katherine; Schools, Zachary L; Che, Tao; Nichols, David E; Shoichet, Brian K; Dror, Ron O; Roth, Bryan L.

Cell; 168(3): 377-389.e12, 2017 01 26.

Artículo en Inglés | MEDLINE | ID: mdl-28129538

3.

Author Correction: Structural insights into µ-opioid receptor activation.

Huang, Weijiao; Manglik, Aashish; Venkatakrishnan, A J; Laeremans, Toon; Feinberg, Evan N; Sanborn, Adrian L; Kato, Hideaki E; Livingston, Kathryn E; Thorsen, Thor S; Kling, Ralf C; Granier, Sébastien; Gmeiner, Peter; Husbands, Stephen M; Traynor, John R; Weis, William I; Steyaert, Jan; Dror, Ron O; Kobilka, Brian K.

Nature; 584(7820): E16, 2020 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-32724208

4.

High diversity in Delta variant across countries revealed by genome-wide analysis of SARS-CoV-2 beyond the Spike protein.

Suratekar, Rohit; Ghosh, Pritha; Niesen, Michiel J M; Donadio, Gregory; Anand, Praveen; Soundararajan, Venky; Venkatakrishnan, A J.

Mol Syst Biol; 18(2): e10673, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35156767

5.

Mechanism of intracellular allosteric ß₂AR antagonist revealed by X-ray crystal structure.

Liu, Xiangyu; Ahn, Seungkirl; Kahsai, Alem W; Meng, Kai-Cheng; Latorraca, Naomi R; Pani, Biswaranjan; Venkatakrishnan, A J; Masoudi, Ali; Weis, William I; Dror, Ron O; Chen, Xin; Lefkowitz, Robert J; Kobilka, Brian K.

Nature; 548(7668): 480-484, 2017 08 24.

Artículo en Inglés | MEDLINE | ID: mdl-28813418

6.

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region.

Venkatakrishnan, A J; Deupi, Xavier; Lebon, Guillaume; Heydenreich, Franziska M; Flock, Tilman; Miljus, Tamara; Balaji, Santhanam; Bouvier, Michel; Veprintsev, Dmitry B; Tate, Christopher G; Schertler, Gebhard F X; Babu, M Madan.

Nature; 536(7617): 484-7, 2016 08 25.

Artículo en Inglés | MEDLINE | ID: mdl-27525504

7.

Diverse GPCRs exhibit conserved water networks for stabilization and activation.

Venkatakrishnan, A J; Ma, Anthony K; Fonseca, Rasmus; Latorraca, Naomi R; Kelly, Brendan; Betz, Robin M; Asawa, Chaitanya; Kobilka, Brian K; Dror, Ron O.

Proc Natl Acad Sci U S A; 116(8): 3288-3293, 2019 02 19.

Artículo en Inglés | MEDLINE | ID: mdl-30728297

8.

Healthcare disparities among anticoagulation therapies for severe COVID-19 patients in the multi-site VIRUS registry.

Kirkup, Christian; Pawlowski, Colin; Puranik, Arjun; Conrad, Ian; O'Horo, John C; Gomaa, Dina; Banner-Goodspeed, Valerie M; Mosier, Jarrod M; Zabolotskikh, Igor Borisovich; Daugherty, Steven K; Bernstein, Michael A; Zaren, Howard A; Bansal, Vikas; Pickering, Brian; Badley, Andrew D; Kashyap, Rahul; Venkatakrishnan, A J; Soundararajan, Venky.

J Med Virol; 93(7): 4303-4318, 2021 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-33666246

9.

Universal allosteric mechanism for Gα activation by GPCRs.

Flock, Tilman; Ravarani, Charles N J; Sun, Dawei; Venkatakrishnan, A J; Kayikci, Melis; Tate, Christopher G; Veprintsev, Dmitry B; Babu, M Madan.

Nature; 524(7564): 173-179, 2015 Aug 13.

Artículo en Inglés | MEDLINE | ID: mdl-26147082

10.

Structural insights into µ-opioid receptor activation.

Huang, Weijiao; Manglik, Aashish; Venkatakrishnan, A J; Laeremans, Toon; Feinberg, Evan N; Sanborn, Adrian L; Kato, Hideaki E; Livingston, Kathryn E; Thorsen, Thor S; Kling, Ralf C; Granier, Sébastien; Gmeiner, Peter; Husbands, Stephen M; Traynor, John R; Weis, William I; Steyaert, Jan; Dror, Ron O; Kobilka, Brian K.

Nature; 524(7565): 315-21, 2015 Aug 20.

Artículo en Inglés | MEDLINE | ID: mdl-26245379

11.

Cerebral Venous Sinus Thrombosis is not Significantly Linked to COVID-19 Vaccines or Non-COVID Vaccines in a Large Multi-State Health System.

Pawlowski, Colin; Rincón-Hekking, John; Awasthi, Samir; Pandey, Viral; Lenehan, Patrick; Venkatakrishnan, A J; Bade, Sairam; O'Horo, John C; Virk, Abinash; Swift, Melanie D; Williams, Amy W; Gores, Gregory J; Badley, Andrew D; Halamka, John; Soundararajan, Venky.

J Stroke Cerebrovasc Dis; 30(10): 105923, 2021 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-34627592

12.

GPCR Dynamics: Structures in Motion.

Latorraca, Naomi R; Venkatakrishnan, A J; Dror, Ron O.

Chem Rev; 117(1): 139-155, 2017 01 11.

Artículo en Inglés | MEDLINE | ID: mdl-27622975

13.

Molecular signatures of G-protein-coupled receptors.

Venkatakrishnan, A J; Deupi, Xavier; Lebon, Guillaume; Tate, Christopher G; Schertler, Gebhard F; Babu, M Madan.

Nature; 494(7436): 185-94, 2013 Feb 14.

Artículo en Inglés | MEDLINE | ID: mdl-23407534

14.

Paediatric safety assessment of BNT162b2 vaccination in a multistate hospital-based electronic health record system in the USA: a retrospective analysis.

Matson, Robert P; Niesen, Michiel J M; Levy, Emily R; Opp, Derek N; Lenehan, Patrick J; Donadio, Greg; O'Horo, John C; Venkatakrishnan, A J; Badley, Andrew D; Soundararajan, Venky.

Lancet Digit Health; 5(4): e206-e216, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36963910

15.

Constrained catecholamines gain ß₂AR selectivity through allosteric effects on pocket dynamics.

Xu, Xinyu; Shonberg, Jeremy; Kaindl, Jonas; Clark, Mary J; Stößel, Anne; Maul, Luis; Mayer, Daniel; Hübner, Harald; Hirata, Kunio; Venkatakrishnan, A J; Dror, Ron O; Kobilka, Brian K; Sunahara, Roger K; Liu, Xiangyu; Gmeiner, Peter.

Nat Commun; 14(1): 2138, 2023 04 14.

Artículo en Inglés | MEDLINE | ID: mdl-37059717

16.

Expanding repertoire of SARS-CoV-2 deletion mutations contributes to evolution of highly transmissible variants.

Venkatakrishnan, A J; Anand, Praveen; Lenehan, Patrick J; Ghosh, Pritha; Suratekar, Rohit; Silvert, Eli; Pawlowski, Colin; Siroha, Abhishek; Chowdhury, Dibyendu Roy; O'Horo, John C; Yao, Joseph D; Pritt, Bobbi S; Norgan, Andrew P; Hurt, Ryan T; Badley, Andrew D; Halamka, John; Soundararajan, Venky.

Sci Rep; 13(1): 257, 2023 01 05.

Artículo en Inglés | MEDLINE | ID: mdl-36604461

17.

Genetic alteration of human MYH6 is mimicked by SARS-CoV-2 polyprotein: mapping viral variants of cardiac interest.

Anand, Praveen; Lenehan, Patrick J; Niesen, Michiel; Yoo, Unice; Patwardhan, Dhruti; Montorzi, Marcelo; Venkatakrishnan, A J; Soundararajan, Venky.

Cell Death Discov; 8(1): 124, 2022 Mar 21.

Artículo en Inglés | MEDLINE | ID: mdl-35314694

18.

On the Origins of Omicron's Unique Spike Gene Insertion.

Venkatakrishnan, A J; Anand, Praveen; Lenehan, Patrick J; Suratekar, Rohit; Raghunathan, Bharathwaj; Niesen, Michiel J M; Soundararajan, Venky.

Vaccines (Basel); 10(9)2022 Sep 09.

Artículo en Inglés | MEDLINE | ID: mdl-36146586

19.

SARS-CoV-2 and influenza coinfection throughout the COVID-19 pandemic: an assessment of coinfection rates, cohort characteristics, and clinical outcomes.

Pawlowski, Colin; Silvert, Eli; O'Horo, John C; Lenehan, Patrick J; Challener, Doug; Gnass, Esteban; Murugadoss, Karthik; Ross, Jason; Speicher, Leigh; Geyer, Holly; Venkatakrishnan, A J; Badley, Andrew D; Soundararajan, Venky.

PNAS Nexus; 1(3): pgac071, 2022 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-35860600

20.

Quantifying the immunological distinctiveness of emerging SARS-CoV-2 variants in the context of prior regional herd exposure.

Niesen, Michiel J M; Murugadoss, Karthik; Lenehan, Patrick J; Marchler-Bauer, Aron; Wang, Jiyao; Connor, Ryan; Brister, J Rodney; Venkatakrishnan, A J; Soundararajan, Venky.

PNAS Nexus; 1(3): pgac105, 2022 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-35899067

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