Asunto(s)
Leucemia-Linfoma de Células T del Adulto/patología , Neoplasias Cutáneas/patología , Adulto , Antígenos CD , Separación Celular , Diagnóstico Precoz , Citometría de Flujo , Humanos , Leucemia-Linfoma de Células T del Adulto/fisiopatología , Linfocitos/patología , Masculino , Fenotipo , Neoplasias Cutáneas/fisiopatologíaRESUMEN
Subcutaneous panniculitis-like T-cell lymphomas (SPTLs) α/ß are rare in childhood. The present report refers to a case of a 7-year-old male child presenting an extensive skin lesion that began when he was 5 years of age. Two biopsies were evaluated using the CD3, CD4, CD8, CD56, ßF1, and TIA markers. A dense infiltrate of CD3+, CD4-, CD8+, CD56-, ßF1+, and TIA+ pleomorphic lymphocytes was found in the subcutis. The previous biopsy showed cytophagic histiocytic panniculitis with a small focus on CD8+ and ßF1+ malignant cells. The lesion regressed spontaneously. This case shows that prognosis may be excellent in SPTL (α/ß). On the other hand, it also serves as an alert that a biopsy performed in an area of cytophagic panniculitis may lead to misdiagnosis.