Detalles de la búsqueda
1.
Utilization of Rosuvastatin and Endogenous Biomarkers in Evaluating the Impact of Ritlecitinib on BCRP, OATP1B1, and OAT3 Transporter Activity.
Pharm Res;
40(11): 2639-2651, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37561322
2.
A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker.
Anal Chem;
92(14): 9745-9754, 2020 07 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32551505
3.
Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1.
Drug Metab Dispos;
47(5): 493-503, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30862625
4.
Perspective: 4ß-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.
Drug Metab Rev;
49(1): 18-34, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27718639
5.
Inception and development of a LC-MS/MS assay for the multiplexed quantitation of nine human drug transporter biomarkers.
Bioanalysis;
16(6): 347-362, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38376139
6.
Study of the ketohexokinase inhibitor PF-06835919 as a clinical cytochrome P450 3A inducer: Integrated use of oral midazolam and liquid biopsy.
Clin Transl Sci;
17(1): e13644, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38108609
7.
Pharmacokinetic interaction between maraviroc and fosamprenavir-ritonavir: an open-label, fixed-sequence study in healthy subjects.
Antimicrob Agents Chemother;
57(12): 6158-64, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24080663
8.
Pharmacokinetics, safety, and tolerability of maraviroc in HIV-negative subjects with impaired renal function.
HIV Clin Trials;
14(3): 99-109, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23835512
9.
Population Pharmacokinetic Modeling for Ceftazidime-Avibactam Renal Dose Adjustments in Pediatric Patients 3 months and Older.
Clin Pharmacol Ther;
113(1): 182-195, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36239478
10.
Effect of Hepatic Impairment on OATP1B Activity: Quantitative Pharmacokinetic Analysis of Endogenous Biomarker and Substrate Drugs.
Clin Pharmacol Ther;
113(5): 1058-1069, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36524426
11.
Evaluation of the Impact of Ritlecitinib on Organic Cation Transporters Using Sumatriptan and Biomarkers as Probes.
J Clin Pharmacol;
63(7): 784-797, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36807251
12.
No effect of a single supratherapeutic dose of lersivirine, a next-generation nonnucleoside reverse transcriptase inhibitor, on corrected QT interval in healthy subjects.
Antimicrob Agents Chemother;
56(5): 2408-13, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22371898
13.
Pharmacokinetic effects of coadministration of lersivirine with raltegravir or maraviroc in healthy subjects.
Antimicrob Agents Chemother;
56(2): 887-92, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22123705
14.
Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-O-desacetyl-rifabutin in healthy subjects.
Antimicrob Agents Chemother;
56(8): 4303-9, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22644026
15.
Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.
Br J Clin Pharmacol;
73(5): 768-75, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22040521
16.
The effect of lersivirine, a next-generation NNRTI, on the pharmacokinetics of midazolam and oral contraceptives in healthy subjects.
Eur J Clin Pharmacol;
68(11): 1567-72, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22527351
17.
A literature review of liver function test elevations in rifampin drug-drug interaction studies.
Clin Transl Sci;
15(7): 1561-1580, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35470578
18.
Leveraging Human Plasma-Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Cytochrome P450 3A4 by Modafinil.
Clin Pharmacol Ther;
111(2): 425-434, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34623637
19.
Development and implementation of urinary transporter biomarkers to facilitate assessment of drug-drug interaction.
Bioanalysis;
14(14): 971-984, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-36066071
20.
Biomarker-Informed Model-Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug-Drug Interactions.
Clin Pharmacol Ther;
111(2): 404-415, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34605015