Laparoscopy treatment of adnexal sterility.

A total of 113 patients who were examined and treated for matrimonial infertility underwent surgical laparoscopy at the Sterility and Infertility Department, Clinic of Gynecology and Obstetrics, Clinical Center of Nis. Age distribution in the group of patients who were subjected to surgical laparoscopy after diagnosis was 31.39 +/- 6.1 years, out of whom 74.3% were treated for primary sterility. Out of corrective interventions in laparoscopy, the following procedures were performed: adnexiolysis, salpingo-ovariolysis, fimbrioplasty, terminal salpingoneostomy, cyst puncture and ovarian incision. During any surgical laparoscopy, ovarian biopsy was performed for evaluation of ovarian potency and verification of probable histopathological findings. The most commonly used technique was salpingo-ovariolysis--in 22.88% of cases, followed by fimbrioplasty--18.81%. A total of 42 pregnancies were verified: 36 intrauterine (29 completed at full term) and 6 extrauterine pregnancies. Average conception rate in our patients was 37.17%, while rate of parturition was 25.66%. The rate of pregnancy in different corrective laparoscopic procedures ranged from 18.18%-61.54%. The rate of intrauterine pregnancy was the highest after bilateral fimbrioplasty (47.83%), and the lowest after bilateral neosalpingostomy--9.09%. The rate of delivery after adhesiolysis was 30.8%, after salpingo-ovariolysis--28.8%, after fimbrioplasty--18.3%, and after neostomy--12.5% of the time.

[Use of low dose lasers in physiatry]. / Primena lasera niske snage u fizijatriji.

The prospective study comprised 105 patients treated for six months in the out-patient and in-patient institutions suffering from the syndrome manifested in pain and disturbed functions due to the diseases of the nerve-muscle and bone-connective tissue systems. The group of patients with the vertebro-basilar syndrome was selected by a single-blind controlled trial while the rest constituted the group whose results were preliminary presented. Two modes of laser photobiostimulation were applied: local stimulation and stimulation of acupuncture points. Evaluation of effects were performed by following up subjective troubles, clinical examinations, laboratory analyses and in patients with the vertebro-basilar syndrome by rheoencephalography in addition. The application of the mentioned methods in different pathological states have shown positive results in 78% of patients with analgesic, spasmolytic and antiadematous effects. In patients with the vertebro-basilar syndrome disappearance of subjective troubles was followed by the improved perfusion in the vertebro-basilar system with the mean increase of the amplitude of the rheoencephalographic curve of 0.063 +/- 0.018 oms and the mean shortening of the anacrotic phase of 0.048 +/- 0.019 seconds.

[Biochemical changes in thrombocyte concentrates stored for 5 days]. / Biohemijske promene u jedinicama koncentrovanih trombocita skladistenih pet dana.

The purpose was to evaluate biochemical and functional changes in platelet concentrates prepared from buffy-coat (PC-BC), stored up to five days at temperature of 20 +/- 2 degrees C. Forty-two PC-BC units from random blood donors were examined. In order to determine the biochemical changes we studied the release of lactate dehidrogenase (LDH), changes in pH value, pCO2, pO2, glucose and lactate concentrations. In addition, the aggregation of platelets with adenosine diphosphate (ADP), and hypotonic shock response were examined. The concentration of LDH markedly increased from 138.8 IU/l (day 1st) up to 234 IU/l (day 5th). The lactate concentration increased significantly (p < 0.001) from 2.1 to 8.6 mmol/l, and consequently pH decrease was observed (from 7.31 to 7.13). The level of glucose decreased gradually from 22.8 to 19.4 mmol/l. The pCO2 decreased progressively from 36.8 mmHg to 24 mmHg during first two days of storage and after that gradually to 20 mmHg. In contrast, pO2 fluctuated between 108 and 133 mmHg during five day of storage. Recovery of hypotonic shock response was 70% on day 1st and 35.7% on day 5th, respectively (p < 0.001). Platelet aggregation using ADP showed significant increase from 6.6 sec (day 1st), to 11.2 sec (day 4th) and 14.6 sec (day 5th), too. Significant differences in biochemical parameters and platelet functions, with confirmed relationship between changes obtained during five days stored PC-BC did not affect the efficacy of applied platelets.