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1.
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Hepatology;
78(3): 709-726, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36999529
2.
Synthesis and labeling of a piperazine-based library of ¹¹C-labeled ligands for imaging of the vesicular acetylcholine transporter.
J Labelled Comp Radiopharm;
57(8): 525-32, 2014 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-24991704
3.
Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors.
Bioorg Med Chem;
19(1): 145-55, 2011 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21183353
4.
Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic.
Bioorg Med Chem Lett;
19(16): 4711-4, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19576765
5.
Radical Functionalization of Unsaturated Amino Acids: Synthesis of Side-Chain-Fluorinated, Azido-Substituted, and Hydroxylated Amino Acids.
ACS Omega;
4(6): 10854-10865, 2019 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31460183
6.
Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.
J Med Chem;
54(11): 3817-26, 2011 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-21524142
7.
Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.
Eur J Med Chem;
45(3): 870-82, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20036448
8.
Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-L-hydroxyproline bioisostere.
Bioorg Med Chem;
15(2): 827-38, 2007 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17107807
9.
Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.
Bioorg Med Chem;
15(22): 7184-202, 2007 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17845856
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