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1.

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.

Odle, Richard I; Walker, Simon A; Oxley, David; Kidger, Andrew M; Balmanno, Kathryn; Gilley, Rebecca; Okkenhaug, Hanneke; Florey, Oliver; Ktistakis, Nicholas T; Cook, Simon J.

Mol Cell; 77(2): 228-240.e7, 2020 01 16.

Artículo en Inglés | MEDLINE | ID: mdl-31733992

2.

Dynamic association of the ULK1 complex with omegasomes during autophagy induction.

Karanasios, Eleftherios; Stapleton, Eloise; Manifava, Maria; Kaizuka, Takeshi; Mizushima, Noboru; Walker, Simon A; Ktistakis, Nicholas T.

J Cell Sci; 126(Pt 22): 5224-38, 2013 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-24013547

3.

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

Dai, Yanfeng; Walker, Simon A; de Vet, Edwin; Cook, Simon; Welch, Heidi C E; Lockyer, Peter J.

J Biol Chem; 286(22): 19905-16, 2011 Jun 03.

Artículo en Inglés | MEDLINE | ID: mdl-21460216

4.

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

Donald, Sarah; Humby, Trevor; Fyfe, Ian; Segonds-Pichon, Anne; Walker, Simon A; Andrews, Simon R; Coadwell, W John; Emson, Piers; Wilkinson, Lawrence S; Welch, Heidi C E.

Proc Natl Acad Sci U S A; 105(11): 4483-8, 2008 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-18334636

5.

Optimized immunofluorescence staining protocol for imaging germinal centers in secondary lymphoid tissues of vaccinated mice.

Fra-Bido, Sigrid; Walker, Simon A; Innocentin, Silvia; Linterman, Michelle A.

STAR Protoc; 2(3): 100499, 2021 09 17.

Artículo en Inglés | MEDLINE | ID: mdl-34195671

6.

ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling.

Dalle Pezze, Piero; Karanasios, Eleftherios; Kandia, Varvara; Manifava, Maria; Walker, Simon A; Gambardella Le Novère, Nicolas; Ktistakis, Nicholas T.

Autophagy; 17(5): 1131-1141, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-32320309

7.

CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+.

Liu, Qing; Walker, Simon A; Gao, Dingcheng; Taylor, James A; Dai, Yan-Feng; Arkell, Rebecca S; Bootman, Martin D; Roderick, H Llewelyn; Cullen, Peter J; Lockyer, Peter J.

J Cell Biol; 170(2): 183-90, 2005 Jul 18.

Artículo en Inglés | MEDLINE | ID: mdl-16009725

8.

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies.

Adalbert, Robert; Nogradi, Antal; Babetto, Elisabetta; Janeckova, Lucie; Walker, Simon A; Kerschensteiner, Martin; Misgeld, Thomas; Coleman, Michael P.

Brain; 132(Pt 2): 402-16, 2009 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-19059977

9.

Autophagosome Biogenesis Machinery.

Walker, Simon A; Ktistakis, Nicholas T.

J Mol Biol; 432(8): 2449-2461, 2020 04 03.

Artículo en Inglés | MEDLINE | ID: mdl-31705882

10.

The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus.

Laser, Heike; Conforti, Laura; Morreale, Giacomo; Mack, Till G M; Heyer, Molly; Haley, Jane E; Wishart, Thomas M; Beirowski, Bogdan; Walker, Simon A; Haase, Georg; Celik, Arzu; Adalbert, Robert; Wagner, Diana; Grumme, Daniela; Ribchester, Richard R; Plomann, Markus; Coleman, Michael P.

Mol Biol Cell; 17(3): 1075-84, 2006 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-16371511

11.

Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.

Zachari, Maria; Gudmundsson, Sigurdur R; Li, Ziyue; Manifava, Maria; Cugliandolo, Fiorella; Shah, Ronak; Smith, Matthew; Stronge, James; Karanasios, Eleftherios; Piunti, Caterina; Kishi-Itakura, Chieko; Vihinen, Helena; Jokitalo, Eija; Guan, Jun-Lin; Buss, Folma; Smith, Andrew M; Walker, Simon A; Eskelinen, Eeva-Liisa; Ktistakis, Nicholas T.

Dev Cell; 50(5): 627-643.e5, 2019 09 09.

Artículo en Inglés | MEDLINE | ID: mdl-31353311

12.

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.

Karanasios, Eleftherios; Walker, Simon A; Okkenhaug, Hanneke; Manifava, Maria; Hummel, Eric; Zimmermann, Hans; Ahmed, Qashif; Domart, Marie-Charlotte; Collinson, Lucy; Ktistakis, Nicholas T.

Nat Commun; 7: 12420, 2016 08 11.

Artículo en Inglés | MEDLINE | ID: mdl-27510922

13.

Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.

Zachari, Maria; Gudmundsson, Sigurdur R; Li, Ziyue; Manifava, Maria; Cugliandolo, Fiorella; Shah, Ronak; Smith, Matthew; Stronge, James; Karanasios, Eleftherios; Piunti, Caterina; Kishi-Itakura, Chieko; Vihinen, Helena; Jokitalo, Eija; Guan, Jun-Lin; Buss, Folma; Smith, Andrew M; Walker, Simon A; Eskelinen, Eeva-Liisa; Ktistakis, Nicholas T.

Dev Cell; 55(2): 251, 2020 Oct 26.

Artículo en Inglés | MEDLINE | ID: mdl-33108756

14.

Control of Ras cycling by Ca2+.

Walker, Simon A; Cullen, Peter J; Taylor, James A; Lockyer, Peter J.

FEBS Lett; 546(1): 6-10, 2003 Jul 03.

Artículo en Inglés | MEDLINE | ID: mdl-12829229

15.

P-Rex2, a new guanine-nucleotide exchange factor for Rac.

Donald, Sarah; Hill, Kirsti; Lecureuil, Charlotte; Barnouin, Romain; Krugmann, Sonja; John Coadwell, W; Andrews, Simon R; Walker, Simon A; Hawkins, Phillip T; Stephens, Len R; Welch, Heidi C E.

FEBS Lett; 572(1-3): 172-6, 2004 Aug 13.

Artículo en Inglés | MEDLINE | ID: mdl-15304343

16.

Characteristics and requirements of basal autophagy in HEK 293 cells.

Musiwaro, Patience; Smith, Matthew; Manifava, Maria; Walker, Simon A; Ktistakis, Nicholas T.

Autophagy; 9(9): 1407-17, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23800949

17.

Live cell imaging of early autophagy events: omegasomes and beyond.

Karanasios, Eleftherios; Stapleton, Eloise; Walker, Simon A; Manifava, Maria; Ktistakis, Nicholas T.

J Vis Exp; (77)2013 Jul 27.

Artículo en Inglés | MEDLINE | ID: mdl-23929131

18.

The immune system GTPase GIMAP6 interacts with the Atg8 homologue GABARAPL2 and is recruited to autophagosomes.

Pascall, John C; Rotondo, Sergio; Mukadam, Aamir S; Oxley, David; Webster, Judith; Walker, Simon A; Piron, Jerry; Carter, Christine; Ktistakis, Nicholas T; Butcher, Geoffrey W.

PLoS One; 8(10): e77782, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24204963

19.

Assembly of early machinery for autophagy induction: novel insights from high resolution microscopy.

Ktistakis, Nicholas T; Walker, Simon A; Karanasios, Eleftherios.

Oncotarget; 7(52): 85678-85679, 2016 12 27.

Artículo en Inglés | MEDLINE | ID: mdl-27829241

20.

Comparison of the T-tubule system in adult rat ventricular and atrial myocytes, and its role in excitation-contraction coupling and inotropic stimulation.

Smyrnias, Ioannis; Mair, Waltraud; Harzheim, Dagmar; Walker, Simon A; Roderick, H Llewelyn; Bootman, Martin D.

Cell Calcium; 47(3): 210-23, 2010 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-20106523

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.

Dynamic association of the ULK1 complex with omegasomes during autophagy induction.

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

Optimized immunofluorescence staining protocol for imaging germinal centers in secondary lymphoid tissues of vaccinated mice.

ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling.

CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+.

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies.

Autophagosome Biogenesis Machinery.

The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus.

Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.

Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.

Control of Ras cycling by Ca2+.

P-Rex2, a new guanine-nucleotide exchange factor for Rac.

Characteristics and requirements of basal autophagy in HEK 293 cells.

Live cell imaging of early autophagy events: omegasomes and beyond.

The immune system GTPase GIMAP6 interacts with the Atg8 homologue GABARAPL2 and is recruited to autophagosomes.

Assembly of early machinery for autophagy induction: novel insights from high resolution microscopy.

Comparison of the T-tubule system in adult rat ventricular and atrial myocytes, and its role in excitation-contraction coupling and inotropic stimulation.