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Org Biomol Chem ; 22(3): 482-485, 2024 Jan 17.
Artículo en Inglés | MEDLINE | ID: mdl-38108209

RESUMEN

An iodine-mediated cyclization has been developed to 4-aryl-NH-1,2,3-triazoles, with p-toluenesulfonyl hydrazide and sulfamic acid used as nitrogen sources. Sulfamic acid plays a crucial role in this reaction by both acting as a substrate and providing an acidic environment. This reaction offers a metal- and azide-free strategy to access NH-1,2,3-triazoles.

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