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1.

School-based allied health interventions for children and young people affected by neurodisability: a systematic evidence map.

McAnuff, Jennifer; Gibson, Jenny L; Webster, Rob; Kaur-Bola, Kulwinder; Crombie, Sarah; Grayston, Aimee; Pennington, Lindsay.

Disabil Rehabil; 45(7): 1239-1257, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-35450497

2.

Evidence for metabolic cleavage of a PEGylated protein in vivo using multiple analytical methodologies.

Elliott, Victoria L; Edge, George T; Phelan, Marie M; Lian, Lu-Yun; Webster, Rob; Finn, Rory F; Park, B Kevin; Kitteringham, Neil R.

Mol Pharm; 9(5): 1291-301, 2012 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-22480236

3.

Medicinal chemistry approaches to avoid aldehyde oxidase metabolism.

Pryde, David C; Tran, Thien-Duc; Jones, Peter; Duckworth, Jonathan; Howard, Martin; Gardner, Iain; Hyland, Ruth; Webster, Rob; Wenham, Tracey; Bagal, Sharan; Omoto, Kiyoyuki; Schneider, Richard P; Lin, Jian.

Bioorg Med Chem Lett; 22(8): 2856-60, 2012 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-22429467

4.

A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder.

Callegari, Ernesto; Malhotra, Bimal; Bungay, Peter J; Webster, Rob; Fenner, Katherine S; Kempshall, Sarah; LaPerle, Jennifer L; Michel, Martin C; Kay, Gary G.

Br J Clin Pharmacol; 72(2): 235-46, 2011 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-21392072

5.

On Washing Away The Stain of Bullying.

Webster, Rob.

Health Serv J; 126(6478): 16-7, 2016 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-30047714

6.

Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.

Hosea, Natilie A; Collard, Wendy T; Cole, Susan; Maurer, Tristan S; Fang, Rick X; Jones, Hannah; Kakar, Shefali M; Nakai, Yasuhiro; Smith, Bill J; Webster, Rob; Beaumont, Kevin.

J Clin Pharmacol; 49(5): 513-33, 2009 May.

Artículo en Inglés | MEDLINE | ID: mdl-19299532

7.

Pyrazole NNRTIs 1: design and initial optimisation of a novel template.

Mowbray, Charles E; Burt, Catherine; Corbau, Romuald; Perros, Manos; Tran, Isabelle; Stupple, Paul A; Webster, Rob; Wood, Anthony.

Bioorg Med Chem Lett; 19(19): 5599-602, 2009 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-19709880

8.

Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate.

Mowbray, Charles E; Burt, Catherine; Corbau, Romuald; Gayton, Simon; Hawes, Michael; Perros, Manos; Tran, Isabelle; Price, David A; Quinton, Faye J; Selby, Matthew D; Stupple, Paul A; Webster, Rob; Wood, Anthony.

Bioorg Med Chem Lett; 19(20): 5857-60, 2009 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-19748778

9.

Pyrazole NNRTIs 3: optimisation of physicochemical properties.

Mowbray, Charles E; Corbau, Romuald; Hawes, Michael; Jones, Lyn H; Mills, James E; Perros, Manos; Selby, Matthew D; Stupple, Paul A; Webster, Rob; Wood, Anthony.

Bioorg Med Chem Lett; 19(19): 5603-6, 2009 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-19717303

10.

The NHS has to shape its own future.

Webster, Rob.

Health Serv J; 124(6403): 18, 2014 Jun 20.

Artículo en Inglés | MEDLINE | ID: mdl-25174235

11.

Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXa^I16L in Preclinical Species.

Parng, Chuenlei; Bolt, Michael; Pittman, Debra D; Caiazzo, Teresa; Dyleski, Lisa; Gorovits, Boris; Webster, Rob.

AAPS J; 21(3): 52, 2019 04 11.

Artículo en Inglés | MEDLINE | ID: mdl-30976993

12.

The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists.

Brown, Alan D; Bunnage, Mark E; Glossop, Paul A; James, Kim; Jones, Rhys; Lane, Charlotte A L; Lewthwaite, Russell A; Mantell, Simon; Perros-Huguet, Christelle; Price, David A; Trevethick, Mike; Webster, Rob.

Bioorg Med Chem Lett; 18(4): 1280-3, 2008 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-18226900

13.

Aspirations of greatness.

Webster, Rob.

Health Serv J; 123(6334): 18, 2013 Jan 10.

Artículo en Inglés | MEDLINE | ID: mdl-23437745

14.

Clinical presentations, treatments and risk factors for mortality in cats with tick paralysis caused by Ixodes holocyclus: 2077 cases (2008-2016).

Leister, Ellie; Morton, John; Atwell, Rick; Webster, Rob.

J Feline Med Surg; 20(6): 465-478, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-28994630

15.

Quantitative biodistribution of biotherapeutics at whole body, organ and cellular levels by autoradiography.

Wang, Mengmeng; Zhan, Yutian; O'Neil, Shawn P; Harris, Stephen; Henson, Claire; McEwen, Andrew; Webster, Rob; O'Hara, Denise M.

Bioanalysis; 10(18): 1487-1500, 2018 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-30198746

16.

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.

Parng, Chuenlei; Singh, Pratap; Pittman, Debra D; Wright, Katherine; Leary, Beth; Patel-Hett, Sunita; Rakhe, Swapnil; Stejskal, James; Peraza, Marjorie; Dufield, Dawn; Murphy, John E; Webster, Rob.

J Pharm Sci; 107(7): 1995-2004, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-29571739

17.

Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.

Jones, Hannah M; Butt, Richard P; Webster, Rob W; Gurrell, Ian; Dzygiel, Pawel; Flanagan, Neil; Fraier, Daniela; Hay, Tanya; Iavarone, Laura Else; Luckwell, Jacquelynn; Pearce, Hannah; Phipps, Alex; Segelbacher, Jill; Speed, Bill; Beaumont, Kevin.

Clin Pharmacokinet; 55(7): 875-887, 2016 07.

Artículo en Inglés | MEDLINE | ID: mdl-26895021

18.

Towards a drug concentration effect relationship for QT prolongation and torsades de pointes.

Webster, Rob; Leishman, Derek; Walker, Don.

Curr Opin Drug Discov Devel; 5(1): 116-26, 2002 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-11865665

19.

The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Partâ1.

Tran, Thien Duc; Wakenhut, Florian; Pickford, Chris; Shaw, Stephen; Westby, Mike; Smith-Burchnell, Caroline; Watson, Lesa; Paradowski, Michael; Milbank, Jared; Brimage, Rebecca A; Halstead, Rebecca; Glen, Rebecca; Wilson, Craig P; Adam, Fiona; Hay, Duncan; Chiva, Jean-Yves; Nichols, Carly; Blakemore, David C; Gardner, Iain; Dayal, Satish; Pike, Andrew; Webster, Rob; Pryde, David C.

ChemMedChem; 9(7): 1378-86, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24729513

20.

The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Partâ2.

Wakenhut, Florian; Tran, Thien Duc; Pickford, Chris; Shaw, Stephen; Westby, Mike; Smith-Burchnell, Caroline; Watson, Lesa; Paradowski, Michael; Milbank, Jared; Stonehouse, David; Cheung, Kathy; Wybrow, Robert; Daverio, Felice; Crook, Samuel; Statham, Keith; Leese, David; Stead, Darren; Adam, Fiona; Hay, Duncan; Roberts, Lee R; Chiva, Jean-Yves; Nichols, Carly; Blakemore, David C; Goetz, Gilles H; Che, Ye; Gardner, Iain; Dayal, Satish; Pike, Andrew; Webster, Rob; Pryde, David C.

ChemMedChem; 9(7): 1387-96, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24729518

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School-based allied health interventions for children and young people affected by neurodisability: a systematic evidence map.

Evidence for metabolic cleavage of a PEGylated protein in vivo using multiple analytical methodologies.

Medicinal chemistry approaches to avoid aldehyde oxidase metabolism.

A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder.

On Washing Away The Stain of Bullying.

Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.

Pyrazole NNRTIs 1: design and initial optimisation of a novel template.

Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate.

Pyrazole NNRTIs 3: optimisation of physicochemical properties.

The NHS has to shape its own future.

Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXa^I16L in Preclinical Species.

The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists.

Aspirations of greatness.

Clinical presentations, treatments and risk factors for mortality in cats with tick paralysis caused by Ixodes holocyclus: 2077 cases (2008-2016).

Quantitative biodistribution of biotherapeutics at whole body, organ and cellular levels by autoradiography.

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.

Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.

Towards a drug concentration effect relationship for QT prolongation and torsades de pointes.

The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Partâ1.

The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Partâ2.