Detalles de la búsqueda
1.
Translational investigation of electrophysiology in hypertrophic cardiomyopathy.
J Mol Cell Cardiol;
157: 77-89, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33957110
2.
Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
Circulation;
137(9): 910-924, 2018 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29167228
3.
ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.
Proc Natl Acad Sci U S A;
112(50): E7003-12, 2015 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26621701
4.
S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.
FASEB J;
30(5): 1849-64, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26839380
5.
Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue.
J Mol Cell Cardiol;
97: 82-92, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27108529
6.
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
J Mol Cell Cardiol;
82: 93-103, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25771144
7.
GSK3ß phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: short communication.
Circ Res;
112(4): 633-9, 2013 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23277198
8.
Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
Circ Res;
112(11): 1491-505, 2013 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-23508784
9.
Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation.
Am J Physiol Heart Circ Physiol;
306(8): H1171-81, 2014 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24585778
10.
Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes.
Arch Biochem Biophys;
554: 11-21, 2014 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24814372
11.
Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium-glucose cotransporter 2 inhibitors.
Cardiovasc Res;
120(3): 301-317, 2024 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38240646
12.
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
Am J Physiol Heart Circ Physiol;
304(2): H260-8, 2013 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23144315
13.
Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy.
J Mol Cell Cardiol Plus;
1: 100007, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37159677
14.
NOX2, p22phox and p47phox are targeted to the nuclear pore complex in ischemic cardiomyocytes colocalizing with local reactive oxygen species.
Cell Physiol Biochem;
27(5): 471-8, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21691064
15.
Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium.
J Muscle Res Cell Motil;
32(3): 221-33, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21959857
16.
Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations.
Cells;
10(12)2021 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34944102
17.
Mutation-specific pathology and treatment of hypertrophic cardiomyopathy in patients, mouse models and human engineered heart tissue.
Biochim Biophys Acta Mol Basis Dis;
1866(8): 165774, 2020 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32217077
18.
Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits.
Antioxid Redox Signal;
31(4): 318-358, 2019 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29490477
19.
Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue.
Sci Rep;
9(1): 18152, 2019 12 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31796859
20.
The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.
J Gen Physiol;
151(1): 18-29, 2019 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30578328