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Int J Neurosci ; 112(9): 1085-98, 2002 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-12487097

RESUMEN

This study investigated the relationship between reported perinatal complications and autism. The biological mothers of 183 autistic children and 209 normals completed the Maternal Perinatal Scale (MPS), a maternal self-report that surveys complications of pregnancies and medical conditions of the mother. Previous research in this area has been limited, with no definitive conclusions. A discriminant analysis was performed to consider perinatal complications as predictors between the autistic and normal subjects. Using the MPS, 65% of the autistic cases were correctly grouped. The results further indicated significant differences on 3 of the 10 factors of the MPS, in particular, Gestational Age, Maternal Morphology, and Intrauterine Stress. When considered in an item by item fashion, 5 items were found to significantly predict group membership (prescriptions taken during pregnancy, length of labor, viral infection, abnormal presentation at delivery, and low birth weight). Finally, 3 maternal medical conditions were found to be highly significant and contribute to the separation between groups, including urinary infection, high temperatures, and depression.


Asunto(s)
Trastorno Autístico/etiología , Complicaciones del Embarazo , Adulto , Trastorno Autístico/epidemiología , Estudios de Casos y Controles , Distribución de Chi-Cuadrado , Niño , Femenino , Humanos , Pruebas de Inteligencia , Masculino , Análisis Multivariante , Pruebas Neuropsicológicas , Perinatología , Valor Predictivo de las Pruebas , Embarazo , Estudios Retrospectivos , Factores de Riesgo
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