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1.

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.

Friscic, Jasna; Böttcher, Martin; Reinwald, Christiane; Bruns, Heiko; Wirth, Benjamin; Popp, Samantha-Josefine; Walker, Kellie Irene; Ackermann, Jochen A; Chen, Xi; Turner, Jason; Zhu, Honglin; Seyler, Lisa; Euler, Maximilien; Kirchner, Philipp; Krüger, René; Ekici, Arif B; Major, Triin; Aust, Oliver; Weidner, Daniela; Fischer, Anita; Andes, Fabian T; Stanojevic, Zeljka; Trajkovic, Vladimir; Herrmann, Martin; Korb-Pap, Adelheid; Wank, Isabel; Hess, Andreas; Winter, Johnathan; Wixler, Viktor; Distler, Jörg; Steiner, Günter; Kiener, Hans P; Frey, Benjamin; Kling, Lasse; Raza, Karim; Frey, Silke; Kleyer, Arnd; Bäuerle, Tobias; Hughes, Timothy R; Grüneboom, Anika; Steffen, Ulrike; Krönke, Gerhard; Croft, Adam P; Filer, Andrew; Köhl, Jörg; Klein, Kerstin; Buckley, Christopher D; Schett, Georg; Mougiakakos, Dimitrios; Hoffmann, Markus H.

Immunity; 54(5): 1002-1021.e10, 2021 05 11.

Artículo en Inglés | MEDLINE | ID: mdl-33761330

2.

Conversion of dendritic cells into tolerogenic or inflammatory cells depends on the activation threshold and kinetics of the mTOR signaling pathway.

Wixler, Viktor; Boergeling, Yvonne; Leite Dantas, Rafael; Varga, Georg; Ludwig, Stephan.

Cell Commun Signal; 22(1): 281, 2024 May 21.

Artículo en Inglés | MEDLINE | ID: mdl-38773618

3.

Small spleen peptides prevent development of psoriatic arthritis via restoration of peripheral tolerance.

Wixler, Viktor; Zaytsev, Igor Z; Leite Dantas, Rafael; Schied, Tanja; Boergeling, Yvonne; Lührmann, Veronika; Varga, Georg; Masemann, Dörthe; Ludwig, Stephan.

Mol Ther; 30(2): 745-762, 2022 02 02.

Artículo en Inglés | MEDLINE | ID: mdl-34450252

4.

Phosphorylation of Influenza A Virus NS1 at Serine 205 Mediates Its Viral Polymerase-Enhancing Function.

Patil, Amol; Anhlan, Darisuren; Ferrando, Verónica; Mecate-Zambrano, Angeles; Mellmann, Alexander; Wixler, Viktor; Boergeling, Yvonne; Ludwig, Stephan.

J Virol; 95(6)2021 02 24.

Artículo en Inglés | MEDLINE | ID: mdl-33408177

5.

Phosphorylation of JIP4 at S730 Presents Antiviral Properties against Influenza A Virus Infection.

Del Sarto, Juliana; Gerlt, Vanessa; Friedrich, Marcel Edgar; Anhlan, Darisuren; Wixler, Viktor; Teixeira, Mauro Martins; Boergeling, Yvonne; Ludwig, Stephan.

J Virol; 95(20): e0067221, 2021 09 27.

Artículo en Inglés | MEDLINE | ID: mdl-34319782

6.

Deficiency of Fhl2 leads to delayed neuronal cell migration and premature astrocyte differentiation.

Kim, Soung Yung; Völkl, Simon; Ludwig, Stephan; Schneider, Holm; Wixler, Viktor; Park, Jung.

J Cell Sci; 132(6)2019 03 18.

Artículo en Inglés | MEDLINE | ID: mdl-30745335

7.

Spontaneous onset of TNFα-triggered colonic inflammation depends on functional T lymphocytes, S100A8/A9 alarmins, and MHC H-2 haplotype.

Leite Dantas, Rafael; Bettenworth, Dominik; Varga, Georg; Weinhage, Toni; Wami, Haleluya Tesfaye; Dobrindt, Ulrich; Roth, Johannes; Vogl, Thomas; Ludwig, Stephan; Wixler, Viktor.

J Pathol; 251(4): 388-399, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32449525

8.

The role of FHL2 in wound healing and inflammation.

Wixler, Viktor.

FASEB J; 33(7): 7799-7809, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-30939249

9.

The Four-and-a-Half LIM Domain Protein 2 Supports Influenza A Virus-Induced Lung Inflammation by Restricting the Host Adaptive Immune Response.

Masemann, Dörthe; Leite Dantas, Rafael; Sitnik, Siarhei; Schied, Tanja; Nordhoff, Carolin; Ludwig, Stephan; Wixler, Viktor.

Am J Pathol; 188(5): 1236-1245, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29458009

10.

The LIM-Only Protein Four and a Half LIM Domain Protein 2 Attenuates Development of Psoriatic Arthritis by Blocking Adam17-Mediated Tumor Necrosis Factor Release.

Leite Dantas, Rafael; Brachvogel, Bent; Schied, Tanja; Bergmeier, Vera; Skryabin, Boris; Vogl, Thomas; Ludwig, Stephan; Wixler, Viktor.

Am J Pathol; 187(11): 2388-2398, 2017 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-28823868

11.

Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked.

Nacken, Wolfgang; Wixler, Viktor; Ehrhardt, Christina; Ludwig, Stephan.

Cell Microbiol; 19(7)2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28076660

12.

Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity.

Kathum, Omer Abid; Schräder, Tobias; Anhlan, Darisuren; Nordhoff, Carolin; Liedmann, Swantje; Pande, Amit; Mellmann, Alexander; Ehrhardt, Christina; Wixler, Viktor; Ludwig, Stephan.

Cell Microbiol; 18(6): 784-91, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-26687707

13.

Macrophage-mediated psoriasis can be suppressed by regulatory T lymphocytes.

Leite Dantas, Rafael; Masemann, Dörthe; Schied, Tanja; Bergmeier, Vera; Vogl, Thomas; Loser, Karin; Brachvogel, Bent; Varga, Georg; Ludwig, Stephan; Wixler, Viktor.

J Pathol; 240(3): 366-377, 2016 11.

Artículo en Inglés | MEDLINE | ID: mdl-27555499

14.

FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.

Wixler, Viktor; Cromme, Christoph; Retser, Eugen; Meyer, Lars-Henrik; Smyth, Neil; Mühlenberg, Katja; Korb-Pap, Adelheid; Koers-Wunrau, Christina; Sotsios, Yannis; Bassel-Duby, Rhonda; Baeten, Dominique; Tak, Paul P; Niederreiter, Birgit; Redlich, Kurt; Bertrand, Jessica; Skryabin, Boris V; Ludwig, Stephan; Pap, Thomas.

Ann Rheum Dis; 74(12): 2216-23, 2015 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-25125695

15.

MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection.

Köther, Katharina; Nordhoff, Carolin; Masemann, Dörthe; Varga, Georg; Bream, Jay H; Gaestel, Matthias; Wixler, Viktor; Ludwig, Stephan.

FASEB J; 28(10): 4235-46, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-24935968

16.

ß-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling.

Hillesheim, Andrea; Nordhoff, Carolin; Boergeling, Yvonne; Ludwig, Stephan; Wixler, Viktor.

Cell Commun Signal; 12: 29, 2014 Apr 26.

Artículo en Inglés | MEDLINE | ID: mdl-24767605

17.

Doxycycline-induced expression of transgenic human tumor necrosis factor α in adult mice results in psoriasis-like arthritis.

Retser, Eugen; Schied, Tanja; Skryabin, Boris V; Vogl, Thomas; Kanczler, Janos M; Hamann, Nina; Niehoff, Anja; Hermann, Sven; Eisenblätter, Michel; Wachsmuth, Lydia; Pap, Thomas; van Lent, Peter L E M; Loser, Karin; Roth, Johannes; Zaucke, Frank; Ludwig, Stephan; Wixler, Viktor.

Arthritis Rheum; 65(9): 2290-300, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23740547

18.

Small Spleen Peptides (SSPs) Shape Dendritic Cell Differentiation through Modulation of Extracellular ATP Synthesis Profile.

Wixler, Viktor; Leite Dantas, Rafael; Varga, Georg; Boergeling, Yvonne; Ludwig, Stephan.

Biomolecules; 14(4)2024 Apr 11.

Artículo en Inglés | MEDLINE | ID: mdl-38672485

19.

A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.

Nordmann, Alexandra; Wixler, Ludmilla; Boergeling, Yvonne; Wixler, Viktor; Ludwig, Stephan.

FASEB J; 26(3): 1290-300, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22106366

20.

The adaptor protein FHL2 enhances the cellular innate immune response to influenza A virus infection.

Nordhoff, Carolin; Hillesheim, Andrea; Walter, Beate M; Haasbach, Emanuel; Planz, Oliver; Ehrhardt, Christina; Ludwig, Stephan; Wixler, Viktor.

Cell Microbiol; 14(7): 1135-47, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22417706

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