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1.
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor.
J Med Chem;
65(9): 6513-6540, 2022 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35468293
2.
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4.
Eur J Med Chem;
178: 530-543, 2019 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31212132
3.
High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors.
ACS Comb Sci;
18(8): 444-55, 2016 08 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27400250
4.
Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties.
J Med Chem;
58(20): 8309-13, 2015 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26356364
5.
Development of a high-throughput screening method for LIM kinase 1 using a luciferase-based assay of ATP consumption.
J Biomol Screen;
17(4): 460-8, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22156225
6.
Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets.
J Med Chem;
55(4): 1731-50, 2012 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-22280363
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