Detalles de la búsqueda
1.
Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking.
Bioorg Med Chem Lett;
30(20): 127478, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32781217
2.
Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting V600EBRAF.
Bioorg Med Chem;
28(11): 115493, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32340792
3.
Design, synthesis, and anticancer activity of imidazo[2,1-b]oxazole-based RAF kinase inhibitors.
Bioorg Chem;
93: 103349, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31627060
4.
Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moieties.
J Enzyme Inhib Med Chem;
34(1): 1534-1543, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31452407
5.
Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors.
Bioorg Med Chem Lett;
28(23-24): 3761-3765, 2018 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30340900
6.
Synthesis of New Triarylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE2 and Nitric Oxide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages.
Molecules;
23(10)2018 Oct 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30301280
7.
Synthesis of novel arylaminoquinazolinylurea derivatives and their antiproliferative activities against bladder cancer cell line.
Bioorg Med Chem Lett;
26(20): 5082-5086, 2016 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27599742
8.
Design, synthesis, and in vitro antiproliferative and kinase inhibitory effects of pyrimidinylpyrazole derivatives terminating with arylsulfonamido or cyclic sulfamide substituents.
J Enzyme Inhib Med Chem;
31(sup2): 111-122, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27255180
9.
Synthesis and broad-spectrum antiproliferative activity of diarylamides and diarylureas possessing 1,3,4-oxadiazole derivatives.
Bioorg Med Chem Lett;
25(8): 1692-1699, 2015 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25801936
10.
Synthesis of quinolinylaminopyrimidines and quinazolinylmethylaminopyrimidines with antiproliferative activity against melanoma cell line.
J Enzyme Inhib Med Chem;
30(4): 607-14, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25431146
11.
Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors.
Bioorg Med Chem;
22(15): 3871-8, 2014 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24997577
12.
HOX-7 suppresses body weight gain and adipogenesis-related gene expression in high-fat-diet-induced obese mice.
BMC Complement Altern Med;
14: 505, 2014 Dec 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-25515293
13.
Cell-based biological evaluation of a new bisamide FMS kinase inhibitor possessing pyrrolo[3,2-c]pyridine scaffold.
Arch Pharm (Weinheim);
347(9): 635-41, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24942978
14.
FMS Kinase Inhibitors: Current Status and Future Prospects.
Med Res Rev;
33(3): 599-636, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22434539
15.
Novel quinolinylaminoisoquinoline bioisosteres of sorafenib as selective RAF1 kinase inhibitors: design, synthesis, and antiproliferative activity against melanoma cell line.
Chem Pharm Bull (Tokyo);
61(7): 747-56, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23812399
16.
Design, synthesis, and antiproliferative activity of new 1H-pyrrolo[3,2-c]pyridine derivatives against melanoma cell lines. Part 2.
Bioorg Med Chem Lett;
22(13): 4362-7, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22647720
17.
New diarylureas and diarylamides possessing acet(benz)amidophenyl scaffold: design, synthesis, and antiproliferative activity against melanoma cell line.
Bioorg Med Chem Lett;
22(9): 3269-73, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22460030
18.
ROS receptor tyrosine kinase: a new potential target for anticancer drugs.
Med Res Rev;
31(5): 794-818, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20687158
19.
Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells.
Bioorg Med Chem;
19(6): 1915-23, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21353571
20.
Synthesis of 1H-pyrazole-1-carboxamide derivatives and their antiproliferative activity against melanoma cell line.
Arch Pharm (Weinheim);
344(3): 197-204, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21384419