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1.
Discovery and anti-tumor activity of 4-(benzylamino)-6-(3,5-dimethylisoxazol-4-yl)quinolin-2(1H)-one (CG13250), a potent, selective and orally bioavailable BET bromodomain inhibitor.
Bioorg Med Chem Lett;
86: 129220, 2023 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36905966
2.
CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia.
Biochem Biophys Res Commun;
590: 49-54, 2022 01 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34971957
3.
CG223, a novel BET inhibitor, exerts TGF-ß1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis.
Pulm Pharmacol Ther;
70: 102057, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34425215
4.
A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression.
Drug Dev Res;
82(8): 1235-1246, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34075610
5.
Lead optimization and efficacy evaluation of quinazoline-based BET family inhibitors for potential treatment of cancer and inflammatory diseases.
Bioorg Med Chem Lett;
29(10): 1220-1226, 2019 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30905542
6.
Trends in Uterine Cervical Cancer Screening at Physical Health Checkups for Company Employees in Japan.
J UOEH;
41(3): 327-333, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31548487
7.
Discovery and lead identification of quinazoline-based BRD4 inhibitors.
Bioorg Med Chem Lett;
28(21): 3483-3488, 2018 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30268702
8.
CG13250, a novel bromodomain inhibitor, suppresses proliferation of multiple myeloma cells in an orthotopic mouse model.
Biochem Biophys Res Commun;
484(2): 262-268, 2017 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28115161
9.
Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma.
Blood Adv;
6(7): 2346-2360, 2022 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35030628
10.
Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4.
Mol Cancer Ther;
18(2): 421-436, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30420565
11.
[The preparatory education of electronic patient record for nursing students before practical nursing training].
J UOEH;
28(4): 431-8, 2006 Dec 01.
Artículo
en Japonés
| MEDLINE | ID: mdl-17209519
12.
BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536.
ACS Med Chem Lett;
6(7): 764-9, 2015 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-26191363
13.
[Development of a hospital information system simulator for education].
J UOEH;
25(2): 217-27, 2003 Jun 01.
Artículo
en Japonés
| MEDLINE | ID: mdl-12813864
14.
Successful antibiotic treatment for a cervical spinal cord abscess following a stab injury on the neck.
Orthopedics;
26(10): 1057-8, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14577529
15.
Reinforcement of saphenous vein graft with ePTFE graft for axillocoronary bypass grafting.
Ann Thorac Surg;
79(2): 700-1, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15680869
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